always give ______ first, then _________
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bronchodilator, then corticosteroid
anorexiants
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low fat diet, BMI > 30, lipase inhibitors, may cause fecal incontinence****
pharmacokinetics
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absorption of drug as it moves through body
olol
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HTN/angina, beta blocker
ADR of Muscle Relaxants
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no reversal agent, euphoria, lightheadedness, dizziness, drowsiness,
fatigue, muscles weakness
what are urinary antispasmodics used for and examples?
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totterodine, oxybutynin, treatment of urinary frequency and urge
incontinence
what do beta blockers end in?
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olol
antimigraine drugs
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serotonin agonists, triptans, vasoconstrict cerebral arteries
prazole
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peptic ulcer disease
stages of drug development
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, - drug evaluation by FDA
- discovery (2-10 yrs)
- preclinical testing: lab/animal testing
- phase I: 20-30 healthy volunteers (safety/dosage)
- phase II: 100-300 patient volunteers with comorbidities (efficacy/side
effects)
- phase III: 1000-3000 patient volunteers (monitor reactions to long term
drug use)
- FDA review/approval
- post market testing
nitrous oxide
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low anesthetic potency, high analgesic potency, N/V
category D
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evidence of human fetal risk (lithium, phenytoin)
weigh benefit against risk
zepam
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bronchodilator, then corticosteroid
anorexiants
Give this one a try later!
low fat diet, BMI > 30, lipase inhibitors, may cause fecal incontinence****
pharmacokinetics
,Give this one a try later!
absorption of drug as it moves through body
olol
Give this one a try later!
HTN/angina, beta blocker
ADR of Muscle Relaxants
Give this one a try later!
no reversal agent, euphoria, lightheadedness, dizziness, drowsiness,
fatigue, muscles weakness
what are urinary antispasmodics used for and examples?
Give this one a try later!
totterodine, oxybutynin, treatment of urinary frequency and urge
incontinence
what do beta blockers end in?
,Give this one a try later!
olol
antimigraine drugs
Give this one a try later!
serotonin agonists, triptans, vasoconstrict cerebral arteries
prazole
Give this one a try later!
peptic ulcer disease
stages of drug development
Give this one a try later!
, - drug evaluation by FDA
- discovery (2-10 yrs)
- preclinical testing: lab/animal testing
- phase I: 20-30 healthy volunteers (safety/dosage)
- phase II: 100-300 patient volunteers with comorbidities (efficacy/side
effects)
- phase III: 1000-3000 patient volunteers (monitor reactions to long term
drug use)
- FDA review/approval
- post market testing
nitrous oxide
Give this one a try later!
low anesthetic potency, high analgesic potency, N/V
category D
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evidence of human fetal risk (lithium, phenytoin)
weigh benefit against risk
zepam
Give this one a try later!
