BSN HESI 215 DOSAGE CALCULATION EXAM V2
COMPREHENSIVE PRACTICE EXAMINATION
2025/2026 QUESTIONS WITH VERIFIED
ANSWERS AND RATIONALES 100% CORRECT |
GRADE A- | NIGHTINGALE STANDARD
EXAMINATION TITLE: BSN HESI 215 Dosage Calculation Exam V2 —
Comprehensive Practice Examination 2025/2026
TOTAL QUESTIONS: 220 Multiple Choice and Calculation Questions
PASSING SCORE: 90% (Equivalent to HESI Standard)
DOMAINS COVERED:
• Domain 1: Basic Dosage Calculations (Questions 1-35)
• Domain 2: Oral Medications (Questions 36-70)
• Domain 3: Injectable Medications (Questions 71-105)
• Domain 4: IV Infusion Calculations (Questions 106-140)
• Domain 5: Pediatric and Weight-Based Calculations (Questions 141-175)
• Domain 6: Complex Calculations and Critical Care (Questions 176-220)
INSTRUCTIONS:
• For questions requiring numeric answers: Enter the numeric value only.
Round as specified.
• For multiple choice questions: Select the best answer.
• Show all work where applicable to demonstrate calculation process.
• All answers are verified with step-by-step rationales.
DOMAIN 1: BASIC DOSAGE CALCULATIONS
,Questions 1-35
Question 1:
The healthcare provider prescribes 500 mg of a medication PO. The medication is
available in 250 mg tablets. How many tablets should the practical nurse
administer? (Enter numeric value only.)
A) 1 tablet
B) 2 tablets
C) 3 tablets
D) 4 tablets
Rationale: 500 mg ÷ 250 mg/tablet = 2 tablets.
Question 2:
A client has a prescription for 0.75 mg/kg IV bolus of a medication to be delivered
over 3 minutes. The client weighs 80 kg. The medication is available for injection
100 mg/20 mL. How many mL should the practical nurse administer? (Enter
numeric value only. Round to nearest tenth.)
A) 10 mL
B) 12 mL
C) 14 mL
D) 16 mL
Rationale: 0.75 mg/kg × 80 kg = 60 mg. 100 mg/20 mL = 5 mg/mL. 60 mg ÷ 5
mg/mL = 12 mL.
Question 3:
A client is receiving acetaminophen (Tylenol) 0.65 gram PO every 6 hours PRN
for pain. Acetaminophen is available in 325 mg tablets. How many milligrams
should the practical nurse administer? (Enter numeric value only.)
A) 325 mg
B) 650 mg
C) 975 mg
D) 1300 mg
,Rationale: 0.65 gram × 1000 mg/gram = 650 mg.
Question 4:
The healthcare provider prescribes acetaminophen elixir (Tylenol elixir) 600 mg
PO q6 hours. The bottle is labeled 500 mg/15 mL. How many mL should the
practical nurse administer? (Enter numeric value only. Round to nearest tenth.)
A) 15 mL
B) 16 mL
C) 17 mL
D) 18 mL
Rationale: 600 mg ÷ (500 mg/15 mL) = 600 ÷ 500 × 15 = 1.2 × 15 = 18 mL.
Question 5:
A client with type 2 diabetes is receiving metformin (Glucophage) 1 gram PO
twice daily. The medication is available in 500 mg tablets. How many tablets
should the practical nurse administer? (Enter numeric value only.)
A) 1 tablet
B) 2 tablets
C) 3 tablets
D) 4 tablets
Rationale: 1 gram × 1000 mg/gram = 1000 mg. 1000 mg ÷ 500 mg/tablet = 2
tablets.
Question 6:
A client who weighs 70 pounds receives a prescription for phenytoin (Dilantin)
PO. The recommended dose is 10 mg/kg/day. How many mg should the PN
determine is the recommended dose? (Enter numeric value only. Round to nearest
whole number.)
A) 316 mg
B) 317 mg
C) 318 mg
D) 319 mg
, Rationale: 70 lb ÷ 2.2 lb/kg = 31.818 kg. 31.818 kg × 10 mg/kg = 318.18 mg.
Round to 318 mg.
Question 7:
A client has a prescription for amoxicillin/clavulanate (Augmentin) 500 mg PO q8
hours. The available form is 250 mg amoxicillin/125 mg clavulanate tablets. How
many tablets should the practical nurse administer for each dose? (Enter numeric
value only.)
A) 1 tablet
B) 2 tablets
C) 3 tablets
D) 4 tablets
Rationale: 500 mg ÷ 250 mg/tablet = 2 tablets.
Question 8:
A client with a gastrostomy tube receives a prescription for a 250 mL bolus
feeding of Glucerna 60% enteral formula. The PN should dilute the full-strength
formula with how many mL of water? (Enter numeric value only.)
A) 100 mL
B) 150 mL
C) 166.7 mL
D) 200 mL
Question 9:
A client is prescribed digoxin 0.125 mg PO daily. The medication is available in
0.25 mg tablets. How many tablets should the practical nurse administer? (Enter
numeric value only.)
A) 0.25 tablet
B) 0.5 tablet
C) 0.75 tablet
D) 1 tablet
Rationale: 0.125 mg ÷ 0.25 mg/tablet = 0.5 tablet.
COMPREHENSIVE PRACTICE EXAMINATION
2025/2026 QUESTIONS WITH VERIFIED
ANSWERS AND RATIONALES 100% CORRECT |
GRADE A- | NIGHTINGALE STANDARD
EXAMINATION TITLE: BSN HESI 215 Dosage Calculation Exam V2 —
Comprehensive Practice Examination 2025/2026
TOTAL QUESTIONS: 220 Multiple Choice and Calculation Questions
PASSING SCORE: 90% (Equivalent to HESI Standard)
DOMAINS COVERED:
• Domain 1: Basic Dosage Calculations (Questions 1-35)
• Domain 2: Oral Medications (Questions 36-70)
• Domain 3: Injectable Medications (Questions 71-105)
• Domain 4: IV Infusion Calculations (Questions 106-140)
• Domain 5: Pediatric and Weight-Based Calculations (Questions 141-175)
• Domain 6: Complex Calculations and Critical Care (Questions 176-220)
INSTRUCTIONS:
• For questions requiring numeric answers: Enter the numeric value only.
Round as specified.
• For multiple choice questions: Select the best answer.
• Show all work where applicable to demonstrate calculation process.
• All answers are verified with step-by-step rationales.
DOMAIN 1: BASIC DOSAGE CALCULATIONS
,Questions 1-35
Question 1:
The healthcare provider prescribes 500 mg of a medication PO. The medication is
available in 250 mg tablets. How many tablets should the practical nurse
administer? (Enter numeric value only.)
A) 1 tablet
B) 2 tablets
C) 3 tablets
D) 4 tablets
Rationale: 500 mg ÷ 250 mg/tablet = 2 tablets.
Question 2:
A client has a prescription for 0.75 mg/kg IV bolus of a medication to be delivered
over 3 minutes. The client weighs 80 kg. The medication is available for injection
100 mg/20 mL. How many mL should the practical nurse administer? (Enter
numeric value only. Round to nearest tenth.)
A) 10 mL
B) 12 mL
C) 14 mL
D) 16 mL
Rationale: 0.75 mg/kg × 80 kg = 60 mg. 100 mg/20 mL = 5 mg/mL. 60 mg ÷ 5
mg/mL = 12 mL.
Question 3:
A client is receiving acetaminophen (Tylenol) 0.65 gram PO every 6 hours PRN
for pain. Acetaminophen is available in 325 mg tablets. How many milligrams
should the practical nurse administer? (Enter numeric value only.)
A) 325 mg
B) 650 mg
C) 975 mg
D) 1300 mg
,Rationale: 0.65 gram × 1000 mg/gram = 650 mg.
Question 4:
The healthcare provider prescribes acetaminophen elixir (Tylenol elixir) 600 mg
PO q6 hours. The bottle is labeled 500 mg/15 mL. How many mL should the
practical nurse administer? (Enter numeric value only. Round to nearest tenth.)
A) 15 mL
B) 16 mL
C) 17 mL
D) 18 mL
Rationale: 600 mg ÷ (500 mg/15 mL) = 600 ÷ 500 × 15 = 1.2 × 15 = 18 mL.
Question 5:
A client with type 2 diabetes is receiving metformin (Glucophage) 1 gram PO
twice daily. The medication is available in 500 mg tablets. How many tablets
should the practical nurse administer? (Enter numeric value only.)
A) 1 tablet
B) 2 tablets
C) 3 tablets
D) 4 tablets
Rationale: 1 gram × 1000 mg/gram = 1000 mg. 1000 mg ÷ 500 mg/tablet = 2
tablets.
Question 6:
A client who weighs 70 pounds receives a prescription for phenytoin (Dilantin)
PO. The recommended dose is 10 mg/kg/day. How many mg should the PN
determine is the recommended dose? (Enter numeric value only. Round to nearest
whole number.)
A) 316 mg
B) 317 mg
C) 318 mg
D) 319 mg
, Rationale: 70 lb ÷ 2.2 lb/kg = 31.818 kg. 31.818 kg × 10 mg/kg = 318.18 mg.
Round to 318 mg.
Question 7:
A client has a prescription for amoxicillin/clavulanate (Augmentin) 500 mg PO q8
hours. The available form is 250 mg amoxicillin/125 mg clavulanate tablets. How
many tablets should the practical nurse administer for each dose? (Enter numeric
value only.)
A) 1 tablet
B) 2 tablets
C) 3 tablets
D) 4 tablets
Rationale: 500 mg ÷ 250 mg/tablet = 2 tablets.
Question 8:
A client with a gastrostomy tube receives a prescription for a 250 mL bolus
feeding of Glucerna 60% enteral formula. The PN should dilute the full-strength
formula with how many mL of water? (Enter numeric value only.)
A) 100 mL
B) 150 mL
C) 166.7 mL
D) 200 mL
Question 9:
A client is prescribed digoxin 0.125 mg PO daily. The medication is available in
0.25 mg tablets. How many tablets should the practical nurse administer? (Enter
numeric value only.)
A) 0.25 tablet
B) 0.5 tablet
C) 0.75 tablet
D) 1 tablet
Rationale: 0.125 mg ÷ 0.25 mg/tablet = 0.5 tablet.
