CLINICAL CHEMISTRY I ASCP ASSESSMENT UPDATED ACTUAL EXAM QUESTIONS CORRECT ANSWERS GRADED A PLUS

CLINICAL CHEMISTRY I ASCP ASSESSMENT UPDATED ACTUAL EXAM QUESTIONS
CORRECT ANSWERS GRADED A PLUS
Clinical Chemistry I ASCP Assessment 2026/2027
Questions and Answers Verified Solutions Latest
Update

Question:
how is HbA1c expressed

Answer:
as a percentage of total Hb



Question:
conditions that can give falsely low HbA1c amount

Answer:
hemolytic anemia (increase in new rbc), recent significant blood loss



Question:
conditions that can give falsely high HbA1c amount

Answer:
iron deficiency anemia, carbamylated hb (attachment of urea formed with renal failure), acetylated
hb, pre-HbA1c or HbS or HbC by electrophoretic or IEC methods)



Question:
glucose tolerance testing

Answer:
3 hour OGTT not recommended for routine testing. 2 hour PP plasma glucose-good alternative



Question:

,gestational diabetes testing

Answer:
screening test, if positive (over 140g/dL), follow by 3 hour OGTT



Question:
normal glucose range and HbA1c

Answer:
74-99mg/dL. HbA1c is 4.0-5.6%



Question:
impaired fasting glucose and HbA1c levels pre-DM

Answer:
100- 125mg/dl, 5.7-6.4%



Question:
impaired glucose tolerance- pre diabetes glucose and HbA1c levels

Answer:
2 hours- 140-199 mg/dL, 5.7-6.4%



Question:
DM glucose and HbA1c levels

Answer:
2 or more- FPG >126mg/dL, 2hr PP >200mg/dL. >6.5%



Question:
GDM glucose and HbA1c levels

,Answer:
2 or more, FPG >95 mg/dL, 1 hr >180 mg/dL, 2hr >155 mg/dL, 3 hrs >140mg/dL



Question:
apolipoprotein

Answer:
protein component that is free from lipids



Question:
total cholesterol reference value

Answer:
<200mg/dL



Question:
Triglycerides reference range

Answer:
<150mg/dl



Question:
HDL-c reference range

Answer:
>55mg/dL



Question:
total cholesterol test

Answer:

, is a coupled enzymatic reaction. cholesterol esterase/cholesterol oxidase and peroxidase form a
chromogen. the specimen is serum or whole blood. sources of interference include excess uric acid,
ascorbic acid, bilirubin or hemolysis



Question:
triglycerides test principle

Answer:
is a lipase/H2O2 coupled method. reaction is lipase/glycerol/kinase/glycerol phosphate oxidase
forming a chromogen. the specimen is fasting serum. sources of interference include excess glycerol
in diabetics, certain medications



Question:
triglycerides test principle for NADH production

Answer:
lipase/glycerol, kinase/pyruvate, kinase/LDH with decrease Abs are key reactions. specimen is
fasting serum. source of interference is hemolysis, excess glycerol.



Question:
which specimen (plasma or serum) is preferred for lipid methods (total cholesterol and triglycerides)

Answer:
levels of EDTA plasma are 4.7% lower than serum due to osmotic shift.



Question:
which test method is usually used for lipoprotein testing?

Answer:
immunological



Question: