OBJECTIVE ASSESSMENT - EXAM
Microbiology Final Exam
Jersey College 2026/2027 |
With Correct Verified
Answers
A+ Verified
| Pathogens,
Edition: 2026/2027
Lab
Passing Score: 80%
Tests, Antibiotics
COVER PAGE - 1
,SECTIONS COVERED
1. 1 - BACTERIAL PATHOGENS & INFECTIONS
2. 2 - VIRAL PATHOGENS & INFECTIONS
3. 3 - FUNGAL & PARASITIC PATHOGENS
4. 4 - DIAGNOSTIC LABORATORY METHODS
5. 5 - ANTIBIOTICS, ANTIMICROBIALS & RESISTANCE
Microbiology Final Exam Jersey College 2026/2027 | With Correct Verified Answer
Instructions: Select the best answer for each question. Each question is worth 1 mark. Passing score: 80%.
SECTION 1: BACTERIAL PATHOGENS & INFECTIONS
Q1.
A 24-year-old college student presents to the campus health clinic with a sore throat, fever of 101.2°F,
and tonsillar exudates. A rapid strep test is positive. The nurse practitioner explains that the most
common causative agent of bacterial pharyngitis in this age group is which of the following organisms.
A. Streptococcus pyogenes (Group A Streptococcus)
B. Staphylococcus aureus
C. Haemophilus influenzae
D. Moraxella catarrhalis
Correct Answer: A
Rationale: Streptococcus pyogenes is the most common bacterial cause of pharyngitis and the target of rapid strep
testing. Staphylococcus aureus typically causes skin infections, not pharyngitis. Haemophilus influenzae is
associated with epiglottitis and meningitis. Moraxella catarrhalis causes otitis media and sinusitis.
, Q2.
A 68-year-old hospitalized patient develops a fever, productive cough with rusty sputum, and pleuritic
chest pain three days after admission. A chest X-ray reveals lobar consolidation. The patient is
diagnosed with hospital-acquired pneumonia. Which virulence factor of Streptococcus pneumoniae is
most responsible for the organism's ability to evade phagocytosis in the alveoli.
A. Polysaccharide capsule
B. Protein A
C. M protein
D. Coagulase
Correct Answer: A
Rationale: The polysaccharide capsule is the primary virulence factor of Streptococcus pneumoniae that prevents
phagocytosis. Protein A is produced by Staphylococcus aureus. M protein is a virulence factor of Streptococcus
pyogenes. Coagulase is produced by Staphylococcus aureus.
Q3.
A wound culture from a diabetic foot ulcer grows gram-positive cocci in clusters that are
catalase-positive and coagulase-positive. The isolate is resistant to methicillin. The microbiology report
confirms this organism as MRSA. The mechanism most commonly responsible for methicillin resistance
in this pathogen involves which genetic element.
A. The mecA gene encoding altered penicillin-binding protein 2a
B. Acquisition of a plasmid carrying the vanA gene
C. Chromosomal mutation in DNA gyrase
D. Loss of the outer membrane porin channels
Correct Answer: A
Rationale: The mecA gene encodes PBP2a, which has low affinity for beta-lactam antibiotics and confers
methicillin resistance in Staphylococcus aureus. The vanA gene confers vancomycin resistance in enterococci.
DNA gyrase mutations cause fluoroquinolone resistance. Porin loss is associated with gram-negative resistance.
Q4.
A 30-year-old woman presents with dysuria, frequency, and urgency. A urine culture grows greater than
100,000 CFU/mL of a gram-negative rod that is lactose-fermenting, oxidase-negative, and produces
indole. This biochemical profile is most consistent with which uropathogen.
A. Escherichia coli
B. Pseudomonas aeruginosa
C. Proteus mirabilis
D. Klebsiella pneumoniae
Correct Answer: A
Rationale: Escherichia coli is the most common cause of uncomplicated UTIs and is lactose-fermenting,
oxidase-negative, and indole-positive. Pseudomonas aeruginosa is oxidase-positive and non-lactose fermenting.
Proteus mirabilis is indole-negative. Klebsiella pneumoniae is indole-negative.
Microbiology Final Exam Jersey College 2026/2027 | With Correct Verified Answers | Pathogens, Lab Tests, Antibiotics Page 3