DISORDERS AND CARDIAC INTERVENTIONS
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,What is the leading cause of death Cardiovascular disease
in the United States?
What is coronary artery disease The most prevalent type of cardiovascular
(CAD)? disease in adults.
What is the most common cause of Coronary atherosclerosis
cardiovascular disease in the U.S.?
What is atherosclerosis? An abnormal accumulation of lipid, fatty
substances, and fibrous tissue in arterial walls.
What initiates the inflammatory Injury to the vascular endothelium.
response in atherosclerosis?
What are foam cells? Macrophages that ingest lipids in the arterial
wall.
What is the consequence of a It attracts platelets and causes thrombus
ruptured plaque in formation, potentially leading to acute coronary
atherosclerosis? syndrome (ACS).
What is myocardial ischemia? A condition where the heart muscle does not
receive enough blood supply.
,What is angina pectoris? Chest pain caused by myocardial ischemia.
What can result from significant Persistently low cardiac output and heart failure.
myocardial damage?
What are atypical symptoms of Indigestion, nausea, palpitations, and numbness.
myocardial ischemia in female
patients?
What is the Framingham Risk To estimate the risk of having a cardiac event
Calculator used for? within the next 10 years.
What are some major risk factors Elevated LDL, diabetes, peripheral arterial
for developing heart disease? disease, and age.
What happens to myocardial cells They are deprived of oxygen needed for
during ischemia? survival.
What is the role of smooth muscle They proliferate and form a fibrous cap over
cells in atherosclerosis? lipid deposits.
What is atheroma? A deposit of lipids and inflammatory infiltrate in
the arterial wall.
, What is the difference between Stable plaques have a thick fibrous cap; unstable
stable and unstable plaques? plaques have a thin cap and ongoing
inflammation.
What can cause sudden cardiac Abrupt cessation of blood supply due to CAD.
death?
What is the significance of the They are particularly susceptible to
coronary arteries' structure? atherosclerosis due to branching and turbulent
blood flow.
What can lead to acute myocardial Obstruction of blood flow due to thrombus
infarction (MI)? formation from ruptured plaques.
What are common symptoms of Chest pain, epigastric distress, and pain
myocardial ischemia? radiating to the jaw or left arm.
What is the relationship between Diabetes is a risk equivalent for CAD, indicating
CAD and diabetes? similar risk for cardiac events.
What is the role of macrophages in They ingest lipids and contribute to the
atherosclerosis? inflammatory response.
What is the outcome of prolonged Irreversible damage and necrosis of myocardial
ischemia? cells.