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Section A: USPSTF Preventive Health Guidelines (20 Questions)
Q1: A 55-year-old asymptomatic woman asks about routine abdominal aortic aneurysm
(AAA) screening. She has never smoked. What does the USPSTF recommend?
A. One-time ultrasound screening at age 55
B. AAA screening every 5 years starting at age 50
C. Routine AAA screening in women who have never smoked is NOT recommended
[CORRECT]
D. Annual palpation of the abdominal aorta
Correct Answer: C
Rationale: The USPSTF recommends against routine AAA screening in women who
have never smoked. AAA screening is recommended for men aged 65–75 who have
ever smoked, not for women without risk factors.
Q2: A 45-year-old man asks his FNP about prostate-specific antigen (PSA) screening.
According to the USPSTF, what is the grade for routine PSA screening for all men?
A. Grade A
B. Grade B
C. Grade C [CORRECT]
D. Grade D
Correct Answer: C
Rationale: Prostate cancer screening with PSA is a USPSTF Grade C recommendation,
meaning clinicians should selectively offer screening based on individual risk and
shared decision-making. It is not a universal Grade A or B recommendation.
,Q3: The USPSTF assigns a Grade A recommendation to which of the following
screening interventions?
A. Teaching breast self-examination
B. Routine PSA screening for all men
C. HIV screening in adolescents and adults aged 15–65 [CORRECT]
D. Routine AAA screening in women
Correct Answer: C
Rationale: HIV screening in adolescents and adults aged 15–65 is a USPSTF Grade A
recommendation. Teaching breast self-exam is not recommended, routine PSA is Grade
C, and routine AAA screening in women is not recommended.
Q4: A 22-year-old sexually active female patient asks when she should begin cervical
cancer screening. According to USPSTF guidelines, screening should begin at what
age?
A. 18 years old, or at onset of sexual activity
B. 21 years old regardless of sexual history [CORRECT]
C. 25 years old if she has had only one partner
D. 30 years old with HPV co-testing
Correct Answer: B
Rationale: The USPSTF recommends starting cervical cancer screening at age 21
regardless of sexual history. Starting earlier does not provide benefit and may lead to
unnecessary procedures.
Q5: A 25-year-old patient has a normal Pap smear. When should her next Pap smear be
performed?
A. In 1 year
B. In 2 years
C. In 3 years [CORRECT]
D. In 5 years
Correct Answer: C
,Rationale: For patients aged 21–29, the USPSTF recommends Pap smear screening
every 3 years. HPV co-testing is not recommended in this age group due to high
transient HPV infection rates.
Q6: A 40-year-old patient asks about cervical cancer screening options. According to
USPSTF guidelines, what is the preferred screening strategy for ages 30–65?
A. Pap smear alone annually
B. Pap smear every 3 years
C. Pap smear plus HPV co-testing every 5 years [CORRECT]
D. HPV testing alone every 10 years
Correct Answer: C
Rationale: For patients aged 30–65, the preferred screening strategy is Pap smear plus
HPV co-testing every 5 years. Pap smear alone every 3 years is an acceptable
alternative.
Q7: A 48-year-old patient asks when to begin colorectal cancer screening. According to
current USPSTF guidelines, screening should begin at what age?
A. 40 years old
B. 45 years old [CORRECT]
C. 50 years old
D. 55 years old
Correct Answer: B
Rationale: The USPSTF recommends starting colorectal cancer screening at age 45 for
average-risk adults. Screening may begin earlier for those with risk factors or family
history.
Q8: A 55-year-old average-risk patient undergoes colonoscopy. If normal, when should
the next colonoscopy be performed?
A. In 3 years
B. In 5 years
C. In 10 years [CORRECT]
, D. Only if symptoms develop
Correct Answer: C
Rationale: For average-risk adults, colonoscopy screening is performed every 10 years
after age 50 (now starting at 45). More frequent intervals are reserved for high-risk
findings.
Q9: A 35-year-old patient with no risk factors asks about breast cancer prevention
counseling. According to the USPSTF, who should receive breast cancer prevention
counseling?
A. All women regardless of risk
B. Only women with a high risk of breast cancer [CORRECT]
C. Only women over age 50
D. Only women with a personal history of breast cancer
Correct Answer: B
Rationale: The USPSTF recommends that clinicians offer to prescribe risk-reducing
medications such as tamoxifen or raloxifene to women at high risk for breast cancer,
not to average-risk women.
Q10: The USPSTF recommends against teaching breast self-examination. What is the
rationale for this recommendation?
A. It increases anxiety without reducing mortality [CORRECT]
B. It is too expensive for patients
C. It requires specialized equipment
D. It is only effective in women over 65
Correct Answer: A
Rationale: The USPSTF recommends against teaching breast self-examination because
it does not reduce breast cancer mortality and may increase harm through false-positive
findings, anxiety, and unnecessary biopsies.