CIC FINAL PAPER EXAM QUESTIONS ACCURATE ANSWERS FULL SOLUTION
CIC Practice EXAM 2026/2027 Premium Review
Questions Accurate Marking Questions and Answers
Verified Solutions Latest Update
Question:
Spec:If someone doesn't have the outcome what's the likelihood of test being negative? Sen: If
someone has outcome what's the likelihood of test being positive.
Answer:
Sensitivity vs specificity
Question:
epidemic spread over a wide geographical area, across countries or continents.
Answer:
Pandemic
Question:
usual incidence of given disease within geographical area during specified time period.
Answer:
Endemic
Question:
excess over the expected incidence of disease within a given geographical area during a specified
time period.
Answer:
Epidemic
,Question:
Incidence- # new cases in population at risk during specified time period Prevalence- # of existent
cases of a given disease at a given time.
Answer:
Incidence vs prevalence
Question:
Incubation period: 2-4 weeks. Clinically asymptomatic, virus disseminated to brain and lymphatic
system, viral load increase, CD4 decreases Acute retroviral syndrome: acute HIV infection.
Manifests in 80-90% of patients lasts less than 2 weeks. Decrease viral load increase CD4 cell
count. HIV serology test is not helpful in this stage. Symptomatic HIV infection: Years of
asymptomatic infection patient develops early symptoms like fever, weight loss, CD4 cell count
ranges 200-500 cells/mm3 AIDS: CD4 count less than 200 cells or severe immune deficiency such
as: Encephalopathy, lymphoma, mycobacterium, recurrent pneumonia, wasting syndrome,
salmonella septicemia recurrent, toxoplasmosis of brain, Kaposi sarcoma, candidiasis, multiple or
recurrent bacterial infections/ Advanced HIV Infection: CD4 cell count <50 cells. Limited life
expectancy.
Answer:
Describe the staged of HIV through a person's lifetime
Question:
Flu like sxs. Paresthesia at or near exposure site. Hyperactivity, agitation, anxiety, fear, sometimes
seizures. Hydrophobia which is fear exhibited at sight of water. Rapidly fatal neurologic disease.
Answer:
SXS Rabies
Question:
Pt immune due to natural infection.
Answer:
HBsAG - NEG anti-HBc - POS anti-HBs - POS What does this mean?
,Question:
Pt is susceptible.
Answer:
HBsAG - NEG anti-HBc - NEG anti-HBs - NEG What does this mean?
Question:
Immune due to HEP B vaccination anti-HBs means antibody hep b SURFACE.
Answer:
HBsAG - NEG anti-HBc - NEG anti-HBs - POS What does this mean?
Question:
Chronically Infected IgM (RECENT infection IgG (OLD infection) anti-HBc - antibody hep b
CORE.
Answer:
HBsAG - POS anti-HBc - POS IgM anti-HBc - NEG anti-HBs - NEG What does this mean?
Question:
Acutely Infected.
Answer:
HBsAG - POS anti-HBc - POS IgM anti-HBc - POS anti-HBs - NEG What does this mean?
Interpretation unclear 4 possibilites: Resolved infection (most common) False-positive anti-HBx,
thus susceptible Low level chronic infection
Question:
Resolving acute infection.
Answer:
HBsAG - NEG anti-HBc - POS anti-HBs - NEG What does this mean?
, Question:
· Confirming the presence of an outbreak · Identifying investigation team and resources · Verifying
the diagnosis · Establishing a preliminary case definition · Alerting administration and key
healthcare partners about the investigation · Performing a detailed literature review · Developing a
methodology for case finding · Preparing an initial line list and epidemic curve · Observing and
reviewing potentially implicated patient care activities · Considering whether environmental
sampling or HCP sampling should be performed · Implementing initial control measures · Defining
and refining the case definition · Continuing case finding and surveillance · Reviewing regularly
control measures · Maintaining surveillance activities · Considering whether an analytic study
should be performed.
Answer:
Steps on conducting an outbreak investigation
Question:
Individuals with and without the EXPOSURE to a potential risk factor that do NOT have the
outcome of interest AT the time of study enrollment Retrospective versus prospective. Need to
follow up for long period of time to see if patient gets the outcome LONG + EXPENSIVE.
Answer:
Cohort Studies
Question:
Measles IgM antibody by EIA - confirms recent measles Measles IgM antibodies may not be
present until 72 hours after rash onset Diagnosis of measles can usually be made on the basis of
clinic presentation alone: cough, coryza (inflammation of mucous membrane in nose), and
conjunctivitis (red eyes) with or w/o Koplik spots (white spots in mouth) Rubella no diagnostic test.
Answer:
MMR Diagnostics and Labs
Question:
Cultures: blood, skin, synovial fluid, CSF infected patients ELISA- detects antibodies followed by
Western Blot for confirmation.
CIC Practice EXAM 2026/2027 Premium Review
Questions Accurate Marking Questions and Answers
Verified Solutions Latest Update
Question:
Spec:If someone doesn't have the outcome what's the likelihood of test being negative? Sen: If
someone has outcome what's the likelihood of test being positive.
Answer:
Sensitivity vs specificity
Question:
epidemic spread over a wide geographical area, across countries or continents.
Answer:
Pandemic
Question:
usual incidence of given disease within geographical area during specified time period.
Answer:
Endemic
Question:
excess over the expected incidence of disease within a given geographical area during a specified
time period.
Answer:
Epidemic
,Question:
Incidence- # new cases in population at risk during specified time period Prevalence- # of existent
cases of a given disease at a given time.
Answer:
Incidence vs prevalence
Question:
Incubation period: 2-4 weeks. Clinically asymptomatic, virus disseminated to brain and lymphatic
system, viral load increase, CD4 decreases Acute retroviral syndrome: acute HIV infection.
Manifests in 80-90% of patients lasts less than 2 weeks. Decrease viral load increase CD4 cell
count. HIV serology test is not helpful in this stage. Symptomatic HIV infection: Years of
asymptomatic infection patient develops early symptoms like fever, weight loss, CD4 cell count
ranges 200-500 cells/mm3 AIDS: CD4 count less than 200 cells or severe immune deficiency such
as: Encephalopathy, lymphoma, mycobacterium, recurrent pneumonia, wasting syndrome,
salmonella septicemia recurrent, toxoplasmosis of brain, Kaposi sarcoma, candidiasis, multiple or
recurrent bacterial infections/ Advanced HIV Infection: CD4 cell count <50 cells. Limited life
expectancy.
Answer:
Describe the staged of HIV through a person's lifetime
Question:
Flu like sxs. Paresthesia at or near exposure site. Hyperactivity, agitation, anxiety, fear, sometimes
seizures. Hydrophobia which is fear exhibited at sight of water. Rapidly fatal neurologic disease.
Answer:
SXS Rabies
Question:
Pt immune due to natural infection.
Answer:
HBsAG - NEG anti-HBc - POS anti-HBs - POS What does this mean?
,Question:
Pt is susceptible.
Answer:
HBsAG - NEG anti-HBc - NEG anti-HBs - NEG What does this mean?
Question:
Immune due to HEP B vaccination anti-HBs means antibody hep b SURFACE.
Answer:
HBsAG - NEG anti-HBc - NEG anti-HBs - POS What does this mean?
Question:
Chronically Infected IgM (RECENT infection IgG (OLD infection) anti-HBc - antibody hep b
CORE.
Answer:
HBsAG - POS anti-HBc - POS IgM anti-HBc - NEG anti-HBs - NEG What does this mean?
Question:
Acutely Infected.
Answer:
HBsAG - POS anti-HBc - POS IgM anti-HBc - POS anti-HBs - NEG What does this mean?
Interpretation unclear 4 possibilites: Resolved infection (most common) False-positive anti-HBx,
thus susceptible Low level chronic infection
Question:
Resolving acute infection.
Answer:
HBsAG - NEG anti-HBc - POS anti-HBs - NEG What does this mean?
, Question:
· Confirming the presence of an outbreak · Identifying investigation team and resources · Verifying
the diagnosis · Establishing a preliminary case definition · Alerting administration and key
healthcare partners about the investigation · Performing a detailed literature review · Developing a
methodology for case finding · Preparing an initial line list and epidemic curve · Observing and
reviewing potentially implicated patient care activities · Considering whether environmental
sampling or HCP sampling should be performed · Implementing initial control measures · Defining
and refining the case definition · Continuing case finding and surveillance · Reviewing regularly
control measures · Maintaining surveillance activities · Considering whether an analytic study
should be performed.
Answer:
Steps on conducting an outbreak investigation
Question:
Individuals with and without the EXPOSURE to a potential risk factor that do NOT have the
outcome of interest AT the time of study enrollment Retrospective versus prospective. Need to
follow up for long period of time to see if patient gets the outcome LONG + EXPENSIVE.
Answer:
Cohort Studies
Question:
Measles IgM antibody by EIA - confirms recent measles Measles IgM antibodies may not be
present until 72 hours after rash onset Diagnosis of measles can usually be made on the basis of
clinic presentation alone: cough, coryza (inflammation of mucous membrane in nose), and
conjunctivitis (red eyes) with or w/o Koplik spots (white spots in mouth) Rubella no diagnostic test.
Answer:
MMR Diagnostics and Labs
Question:
Cultures: blood, skin, synovial fluid, CSF infected patients ELISA- detects antibodies followed by
Western Blot for confirmation.
