NUR 6121 EXAM 3
1. What is gout?
*Answer√√ A systemic hereditary autoimmune metabolic disease caused by deposition of monosodium urate
crystals due to hyperuricemia.
2. What uric acid level causes crystal formation?
*Answer√√ >6.8 mg/dL
3. What causes hyperuricemia?
*Answer√√ Increased uric acid production, decreased renal excretion, or both.
4. Does hyperuricemia always cause gout?
*Answer√√ No, it can be asymptomatic for years.
5. Primary hyperuricemia cause?
*Answer√√ Inborn metabolic error.
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,6. Secondary hyperuricemia cause?
*Answer√√ Disease or medications.
7. Most common inflammatory arthritis
*Answer√√ Gout
8. Most common joint affected in gout
*Answer√√ 1st MTP joint (podagra)
9. Classic gout flare symptoms
*Answer√√ Pain, redness, swelling, warmth, decreased ROM.
10. When do gout flares often occur?
*Answer√√ At night
11. Gold standard for gout diagnosis
*Answer√√ Needle aspiration showing MSU crystals.
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, 12. Four stages of gout
*Answer√√ Asymptomatic hyperuricemia, Acute flare, Intercritical gout, Chronic tophaceous
gout.
13. First-line treatment for acute gout
*Answer√√ NSAIDs
14. Colchicine mechanism
*Answer√√ Inhibits neutrophil migration.
15. Goal uric acid level in gout
*Answer√√ 6d mg/dL
16. First-line urate-lowering therapy
*Answer√√ Allopurinol
17. When to start urate-lowering therapy
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1. What is gout?
*Answer√√ A systemic hereditary autoimmune metabolic disease caused by deposition of monosodium urate
crystals due to hyperuricemia.
2. What uric acid level causes crystal formation?
*Answer√√ >6.8 mg/dL
3. What causes hyperuricemia?
*Answer√√ Increased uric acid production, decreased renal excretion, or both.
4. Does hyperuricemia always cause gout?
*Answer√√ No, it can be asymptomatic for years.
5. Primary hyperuricemia cause?
*Answer√√ Inborn metabolic error.
1/
19
,6. Secondary hyperuricemia cause?
*Answer√√ Disease or medications.
7. Most common inflammatory arthritis
*Answer√√ Gout
8. Most common joint affected in gout
*Answer√√ 1st MTP joint (podagra)
9. Classic gout flare symptoms
*Answer√√ Pain, redness, swelling, warmth, decreased ROM.
10. When do gout flares often occur?
*Answer√√ At night
11. Gold standard for gout diagnosis
*Answer√√ Needle aspiration showing MSU crystals.
2/
19
, 12. Four stages of gout
*Answer√√ Asymptomatic hyperuricemia, Acute flare, Intercritical gout, Chronic tophaceous
gout.
13. First-line treatment for acute gout
*Answer√√ NSAIDs
14. Colchicine mechanism
*Answer√√ Inhibits neutrophil migration.
15. Goal uric acid level in gout
*Answer√√ 6d mg/dL
16. First-line urate-lowering therapy
*Answer√√ Allopurinol
17. When to start urate-lowering therapy
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19
