NRSG 210 Questions and Already
Solved Solutions.
When is it not appropriate for a brand name drug to be substituted with a generic drug (2)? -
Answer Critical care drug
Drugs with a narrow safety margin
What is the definition of bioavailability? - Answer Rate and extent active ingredients are
absorbed from a drug product and then available at site of action
What are 4 factor that affect bioavailability? - Answer 1) Different trade vs generic
2)Inert or active ingredients
3)Rate of absorption
4)Tablet compression (extended release)
What are 7 things nurses must know about drug? - Answer 1)What drug is ordered and why
2)Intended use
3)Special considerations
4)Effects on body
5)Contraindications and precautions
6)Adverse effects
7)Name of drug
5 things nurse MUST obtain before administrating a medication - Answer Learning
capabilities of patient
Physical assessment
History (medical history)
Allergies
Medications
Ch 3
What is the first-pass effect?
What might happen because of this? - Answer Drugs absorbed from the stomach and small
intestine travel to liver, where they are inactivated before reaching target organ
, Patients might require a larger dose of oral meds than IV meds
What route avoids first-pass effect? - Answer Rectal route
5 factors of rectal route - Answer -Local or systemic
-Safe, effective or comatose patients
-Suppository or enema
-Avoids first=pass effect
-May stimulate vagus response (decreases HR)
What 2 hormones are increased during pregnancy? - Answer Progesterone
Estrogen
How does increased levels of progesterone affect the body? - Answer Increases pulmonary
blood which increases absorption rates of respiratory agents like cromolyn (Intal)
How does increased levels of estrogen affect the body (2)? - Answer Delays gastric emptying
and increases stomach acid
Extended/decreased absorption time for oral drugs
What 2 things are affected during pregnancy? Which one is least affected? - Answer
Metabolism-least affected
Excretion
How is metabolism affected during pregnancy? - Answer Drugs like nicotine can increase
amounts of placental metabolic enzymes
Fetal liver is still developing and lacks ability to metabolize drugs mom takes
How is excretion affected during pregnancy? - Answer Increased during pregnancy
Dosage of many medications must be adjusted
5 factors that determine amount of drug that passes from breast milk to infant during lactation -
Answer Plasma drug level in mother
Drug Solubility
Molecule size and protein binding
Drug ionization
Solved Solutions.
When is it not appropriate for a brand name drug to be substituted with a generic drug (2)? -
Answer Critical care drug
Drugs with a narrow safety margin
What is the definition of bioavailability? - Answer Rate and extent active ingredients are
absorbed from a drug product and then available at site of action
What are 4 factor that affect bioavailability? - Answer 1) Different trade vs generic
2)Inert or active ingredients
3)Rate of absorption
4)Tablet compression (extended release)
What are 7 things nurses must know about drug? - Answer 1)What drug is ordered and why
2)Intended use
3)Special considerations
4)Effects on body
5)Contraindications and precautions
6)Adverse effects
7)Name of drug
5 things nurse MUST obtain before administrating a medication - Answer Learning
capabilities of patient
Physical assessment
History (medical history)
Allergies
Medications
Ch 3
What is the first-pass effect?
What might happen because of this? - Answer Drugs absorbed from the stomach and small
intestine travel to liver, where they are inactivated before reaching target organ
, Patients might require a larger dose of oral meds than IV meds
What route avoids first-pass effect? - Answer Rectal route
5 factors of rectal route - Answer -Local or systemic
-Safe, effective or comatose patients
-Suppository or enema
-Avoids first=pass effect
-May stimulate vagus response (decreases HR)
What 2 hormones are increased during pregnancy? - Answer Progesterone
Estrogen
How does increased levels of progesterone affect the body? - Answer Increases pulmonary
blood which increases absorption rates of respiratory agents like cromolyn (Intal)
How does increased levels of estrogen affect the body (2)? - Answer Delays gastric emptying
and increases stomach acid
Extended/decreased absorption time for oral drugs
What 2 things are affected during pregnancy? Which one is least affected? - Answer
Metabolism-least affected
Excretion
How is metabolism affected during pregnancy? - Answer Drugs like nicotine can increase
amounts of placental metabolic enzymes
Fetal liver is still developing and lacks ability to metabolize drugs mom takes
How is excretion affected during pregnancy? - Answer Increased during pregnancy
Dosage of many medications must be adjusted
5 factors that determine amount of drug that passes from breast milk to infant during lactation -
Answer Plasma drug level in mother
Drug Solubility
Molecule size and protein binding
Drug ionization
