Practice Questions with Answers, Rationales, and Key Concepts
for Cardiovascular, Respiratory, Renal, GI, Endocrine,
Neurological, Hematologic, and Oncology Disorders Download
now and pass first try!
Exam Information
Course: WGU D444 Adult Health 1
Assessment: Objective Assessment (OA) – Versions 1 and 2
Target Audience: WGU nursing students
Core Domains Covered: Cardiovascular disorders, respiratory conditions, renal and
urinary disorders, gastrointestinal disorders, endocrine disorders, neurological disorders,
hematologic and immunologic disorders, oncology, fluid/electrolyte/acid-base balance,
perioperative care, pharmacology, and prioritization/delegation
Question Format: Multiple-choice, Next Generation NCLEX (NGN)-style, select-all-that-
apply, and bowtie diagrams
Duration: 3 hours
Key Topics to Study
Category Specific Focus Areas
,Cardiovascular Heart failure (left/right-sided), myocardial infarction,
hypertension, dysrhythmias, warfarin therapy, beta-
blockers, calcium channel blockers
Respiratory COPD, asthma, pneumonia, oxygen therapy, chest
tubes, ABG interpretation
Renal/Urinary Acute kidney injury, chronic kidney disease, renal
calculi, fluid/electrolyte imbalances
Gastrointestinal GI bleeding, liver disease, pancreatitis, nutrition
Endocrine Diabetes mellitus, thyroid disorders (levothyroxine),
Cushing's syndrome, adrenal disorders
Neurological Stroke, seizures, increased intracranial pressure,
neurological assessments
Hematologic/Immunologic Anemia, coagulation disorders, warfarin monitoring
(INR), autoimmune conditions
Oncology Cancer treatments, radiation skin care,
chemotherapy side effects
Fluid/Electrolytes Hyponatremia, hyperkalemia, dehydration, fluid
volume excess
Perioperative Preoperative assessment, latex allergies,
postoperative care, wound healing
Integumentary Burns, wound care, eczema treatment
Pharmacology Medication administration, side effects, monitoring
parameters, patient education
, SECTION 1: CARDIOVASCULAR DISORDERS (Questions 1-40)
1. A nurse is assessing a client with left-sided heart failure. Which of the following
findings is most consistent with this condition?
A) Peripheral edema and jugular venous distention
B) Dyspnea, orthopnea, and crackles in the lungs
C) Hepatomegaly and ascites
D) Weight gain and abdominal bloating
Answer: B. Left-sided heart failure causes backup of blood into the pulmonary circulation,
resulting in pulmonary symptoms (dyspnea, orthopnea, paroxysmal nocturnal dyspnea,
crackles). Peripheral edema, JVD, hepatomegaly, and ascites are signs of right-sided heart
failure.
2. A client is admitted with acute myocardial infarction (MI). Which of the following
should the nurse expect to administer immediately?
A) Morphine, oxygen, nitroglycerin, aspirin (MONA)
B) Heparin, warfarin, clopidogrel
C) Furosemide, digoxin, enalapril
D) Albuterol, ipratropium, methylprednisolone
Answer: A. The MONA protocol (Morphine, Oxygen, Nitroglycerin, Aspirin) is the standard
immediate treatment for acute MI.
3. A client is receiving warfarin therapy. Which laboratory value should the nurse
monitor most closely?
A) Hemoglobin A1C
, B) Serum potassium
C) International Normalized Ratio (INR)
D) White blood cell count
Answer: C. INR is the primary monitoring parameter for warfarin therapy to ensure
therapeutic anticoagulation and prevent bleeding complications.
4. A patient with chronic systolic heart failure (LVEF 35%) on metoprolol succinate
presents with acute dyspnea. Vital signs: BP 92/58 mm Hg, HR 54 bpm, respiratory
rate 28. Crackles halfway up lung fields. Which intervention is most appropriate
regarding the beta-blocker?
A) Continue the beta-blocker as prescribed
B) Withhold the beta-blocker
C) Administer IV beta-agonist
D) Double the beta-blocker dose
Answer: B. In acute decompensated heart failure with hemodynamic instability (SBP < 90-
100, bradycardia), beta-blockers should be temporarily withheld.
5. A nurse is caring for a client with heart failure. Which finding indicates fluid
volume excess?
A) Dry mucous membranes
B) Weight loss of 2 lb in 24 hours
C) Bilateral crackles in the lungs
D) Decreased jugular venous distention
Answer: C. Bilateral crackles indicate pulmonary congestion from fluid accumulation in the
alveoli, a hallmark of left-sided heart failure and fluid volume excess.