WGU D116 FINAL PAPER UPDATED
QUESTIONS VERIFIED COMPLETE
ANSWERS 100 PERCENT CORRECT
◉ A patient with gout who has increasingly frequent acute gouty
attacks will begin receiving allopurinol and colchicine.
Which statement should be included when teaching the patient
about this drug regimen?
Answer: "Allopurinol reduces the likelihood of gouty episodes that
usually occur with initial colchicine therapy."
NO "Colchicine is given to enhance the effects of allopurinol."
"Allopurinol helps reduce the gastrointestinal side effects of
colchicine."
YES "You will take both drugs initially and then stop taking
colchicine."
Incorrect. Colchicine does not enhance the effects of allopurinol.
Correct! Colchicine is used for prophylaxis when urate-lowering
drugs, such as allopurinol, are initiated because gouty episodes often
increase during this time. Patients start with both drugs and
ultimately withdraw the colchicine.
,◉ A postmenopausal patient develops osteoporosis. The patient
asks the provider about medications to treat this condition. The
provider learns that the patient has a family history of breast cancer.
Which medication should the provider discuss with the patient?
Answer: Estrogen estradiol
Teriparatide
Pamidronate
YES Raloxifene
Correct! Raloxifene is a selective estrogen receptor modulator
(SERM) that has estrogenic effects in some tissues and
antiestrogenic effects in others. It can preserve bone mineral density
while protecting against breast and endometrial cancers.
◉ Which of the following antibiotics is in a class of drugs known for
ototoxicity?
Answer: YES Gentamicin
Sulfamethoxazole
Cefazolin
Imipenem
Correct! Gentamicin is an aminoglycoside antibiotic which, as a class,
is known to cause ototoxicity.
◉ What is the role of oral corticosteroids in the treatment of
rheumatoid arthritis?
,Answer: YES Short-term therapy for flares in patients with
established disease
Disease-modifying antirheumatic drug (DMARD) monotherapy
Reducing adverse effects in patients taking methotrexate
Combination therapy during the first year of treatment with a
disease-modifying antirheumatic drugs (DMARD)
Correct! Corticosteroids are effective in the treatment of rheumatoid
arthritis by slowing the progression of erosions. However, their long-
term use in patients with rheumatoid arthritis is limited by their
breadth of adverse effects.
◉ What is a recommended strategy for patients to do prior to
injecting disease-modifying antirheumatic drugs (DMARDs) to
decrease the pain of the injection?
Answer: Take an oral antihistamine 30 minutes before the injection
YES Allow the injection to come to room temperature
Use a topical anesthetic
Take prednisone 5 mg 30 minutes before the injection
Correct! DMARDs are refrigerated and may cause discomfort upon
injection if they are not allowed to come to room temperature.
◉ Which traditional disease-modifying antirheumatic drug
(DMARD) may be the best option in a pregnant patient with
rheumatoid arthritis?
, Answer: Cyclophosphamide
Leflunomide
YES Hydroxychloroquine
Methotrexate
Correct! Hydroxychloroquine is used in pregnancy and should be
monitored closely. Literature regarding human pregnancies and
hydroxychloroquine demonstrated no increase in the rate of birth
defects.
◉ Which of the following is false about methotrexate?
Answer: YES Subcutaneous use requires folic acid replacement of 1
mg per day.
If folic acid is needed to reduce side effects, a dose of 1 mg daily or 5
mg once weekly on the day following the methotrexate dose is
recommended.
Methotrexate may be used as monotherapy or in combination with
biologics.
Male and female patients should use contraception while using
methotrexate.
Correct! Folic acid replacement is used to reduce side effects of
methotrexate and is used orally and subcutaneously. Although folic
acid replacement is common and efficacious, its use is not required.
◉ For which antibiotic is time above the minimum inhibitory
concentration (MIC) most important?
QUESTIONS VERIFIED COMPLETE
ANSWERS 100 PERCENT CORRECT
◉ A patient with gout who has increasingly frequent acute gouty
attacks will begin receiving allopurinol and colchicine.
Which statement should be included when teaching the patient
about this drug regimen?
Answer: "Allopurinol reduces the likelihood of gouty episodes that
usually occur with initial colchicine therapy."
NO "Colchicine is given to enhance the effects of allopurinol."
"Allopurinol helps reduce the gastrointestinal side effects of
colchicine."
YES "You will take both drugs initially and then stop taking
colchicine."
Incorrect. Colchicine does not enhance the effects of allopurinol.
Correct! Colchicine is used for prophylaxis when urate-lowering
drugs, such as allopurinol, are initiated because gouty episodes often
increase during this time. Patients start with both drugs and
ultimately withdraw the colchicine.
,◉ A postmenopausal patient develops osteoporosis. The patient
asks the provider about medications to treat this condition. The
provider learns that the patient has a family history of breast cancer.
Which medication should the provider discuss with the patient?
Answer: Estrogen estradiol
Teriparatide
Pamidronate
YES Raloxifene
Correct! Raloxifene is a selective estrogen receptor modulator
(SERM) that has estrogenic effects in some tissues and
antiestrogenic effects in others. It can preserve bone mineral density
while protecting against breast and endometrial cancers.
◉ Which of the following antibiotics is in a class of drugs known for
ototoxicity?
Answer: YES Gentamicin
Sulfamethoxazole
Cefazolin
Imipenem
Correct! Gentamicin is an aminoglycoside antibiotic which, as a class,
is known to cause ototoxicity.
◉ What is the role of oral corticosteroids in the treatment of
rheumatoid arthritis?
,Answer: YES Short-term therapy for flares in patients with
established disease
Disease-modifying antirheumatic drug (DMARD) monotherapy
Reducing adverse effects in patients taking methotrexate
Combination therapy during the first year of treatment with a
disease-modifying antirheumatic drugs (DMARD)
Correct! Corticosteroids are effective in the treatment of rheumatoid
arthritis by slowing the progression of erosions. However, their long-
term use in patients with rheumatoid arthritis is limited by their
breadth of adverse effects.
◉ What is a recommended strategy for patients to do prior to
injecting disease-modifying antirheumatic drugs (DMARDs) to
decrease the pain of the injection?
Answer: Take an oral antihistamine 30 minutes before the injection
YES Allow the injection to come to room temperature
Use a topical anesthetic
Take prednisone 5 mg 30 minutes before the injection
Correct! DMARDs are refrigerated and may cause discomfort upon
injection if they are not allowed to come to room temperature.
◉ Which traditional disease-modifying antirheumatic drug
(DMARD) may be the best option in a pregnant patient with
rheumatoid arthritis?
, Answer: Cyclophosphamide
Leflunomide
YES Hydroxychloroquine
Methotrexate
Correct! Hydroxychloroquine is used in pregnancy and should be
monitored closely. Literature regarding human pregnancies and
hydroxychloroquine demonstrated no increase in the rate of birth
defects.
◉ Which of the following is false about methotrexate?
Answer: YES Subcutaneous use requires folic acid replacement of 1
mg per day.
If folic acid is needed to reduce side effects, a dose of 1 mg daily or 5
mg once weekly on the day following the methotrexate dose is
recommended.
Methotrexate may be used as monotherapy or in combination with
biologics.
Male and female patients should use contraception while using
methotrexate.
Correct! Folic acid replacement is used to reduce side effects of
methotrexate and is used orally and subcutaneously. Although folic
acid replacement is common and efficacious, its use is not required.
◉ For which antibiotic is time above the minimum inhibitory
concentration (MIC) most important?
