7/26/26, 9:18 AM NU 545 Unit 4 EXAM - 2026 (Questions + Answers) with verified Answers (Latest Update 2026) UPDATE!! Compliance Tips & How …
NU 545 Unit 4 EXAM - 2026 (Questions + Answers)
with verified Answers (Latest Update 2026)
UPDATE!! Compliance Tips & How to Pass Fast
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Terms in this set (79)
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,7/26/26, 9:18 AM NU 545 Unit 4 EXAM - 2026 (Questions + Answers) with verified Answers (Latest Update 2026) UPDATE!! Compliance Tips & How …
Infectious Mononucleosis (IM) p. 945 A benign, acute, self-limiting lymphoproliferative
clinical syndrome characterized by acute viral
infection of B lymphocytes (B cells). Associated with
several tumors, such as B cell and T cell, Hodgkin
lymphoma (HL) and nasopharyngeal carcinoma.
Linked to post-transplant lymphoproliferative diseases
(PTLD) and gastric carcinoma. Most common cause-
EBV (herpes virus). 90% of people have antibodies,
early infections rarely develop into IM. During
adolescence or later 35-50% get IM (p945).
Transmission of EBV: Saliva (Kissing Disease),
secretions of genital, rectal, resp tract & blood,
cervical and seminal fluid.. No aerosol transmission.
Disease begins with widespread infection of B
lymphocytes which have receptors for EBV. Virus
initially infects oropharynx, nasopharynx, and salivary
epithelial cells then spreads to lymphoid tissue and B
cells. Infection of B cells allows the virus to enter the
bloodstream, then the virus spreads systemically
(p946)
Patho of Infectious Mononucleosis p. Immunodeficiency, infected B cells may be
946 uncontrolled and lead to B-cell lymphoma. In the
immunocompetent patient, unaffected B cells
produce antibodies (IgG, IgM, IgA) against the virus.
There is a massive activation of proliferation of
cytotoxic T cells (CD8) directed against EBV infected
cells. Immune response against EBV is largely
responsible for cellular proliferation in the lymphoid
tissue (lymph nodes, spleen, tonsils, liver). Sore throat
and fever are the earliest manifestations d/t
inflammation at the site of viral entry and initial
infection, usually the mouth and throat.
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,7/26/26, 9:18 AM NU 545 Unit 4 EXAM - 2026 (Questions + Answers) with verified Answers (Latest Update 2026) UPDATE!! Compliance Tips & How …
Clinical manifestations of infectious Pharyngitis (sore throat), lymphadenopathy, and fever
mononucleosis p. 946 (p945). Incubation period: 30-50 days (4-8 weeks),
then a 3-5 day prodrome of HA, fever, malaise,
arthralgias ( joint pain). cervical lymph nodes.
Pharyngitis: whitish, greyish green thick exudate.
Severe complications: meningitis, encephalitis, guillain
barre syndrome, bells palsy, optic neuritis, mental
impairment, transverse myelitis, cerebellar ataxia,
demyelinating disease.
Ocular manifestations: eyelid/periorbital edema, dry
eyes, keratitis, uveitis, conjunctivitis, retinitis,
oculoglandular syndrome, choroiditis, papillitis,
ophthalmoplegia.
In child: Reye syndrome.
Pulmonary involvement: RARE- hilar and mediastinal
lymphadenopathy, interstitial pneumonitis, pleural
effusions, pneumonia and resp fail in
immunocompromised patient. Older patient with 2
weeks of temp that can't be explained EBV should be
suspected, Most common cause of death is splenic
rupture (rare, 0.1-0.5%) r/t mild trauma in men <25
between 4 and 21 days after symptoms. Other deaths:
hepatic failure, bacterial infection, viral myocarditis.
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, 7/26/26, 9:18 AM NU 545 Unit 4 EXAM - 2026 (Questions + Answers) with verified Answers (Latest Update 2026) UPDATE!! Compliance Tips & How …
Eval and Tx of infectious Children present w/: fever, pharyngitis (sore throat),
mononucleosis p. 947 lymphadenitis.
Young adults present w/: malaise, fatigue,
lymphadenopathy and fever of unknown origin.
Palatal petechiae (redish-brown spots on roof of
mouth), splenomegaly, and posterior cervical
adenopathy (lymphnodes).
Blood contains increased WBC (lymphocytes).
Dx based on Hoagland's criteria: 50% lymphocytes,
10% atypical lymphocytes in the blood with positive
heterophile antibody (IgM) with Monospot test.
presence of fever, pharyngitis, adenopathy confirmed
by a + serologic test. Serological test: heterophile
antibodies,
Monospot test (limited b/c CMV, adenovirus,
toxoplasmosis also produce heterophilic antibodies
causing false +).
Tx: IM is usually self limiting and intervention is rarely
required. Rest & alleviation of symptoms. No ASA used
with child or adolescent d/t reye syndrome.
Streptococcal pharyngitis (20-30% cases) tx w/ PCN
or erythromycin. NO ampicillin (causes rash in patients
with IM). Avoid strenuous activities. Steroids only with
severe complications (airway obstruction). Acyclovir
with immunocompromised pts.
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NU 545 Unit 4 EXAM - 2026 (Questions + Answers)
with verified Answers (Latest Update 2026)
UPDATE!! Compliance Tips & How to Pass Fast
Add to calendar
Play your way to mastery with fun games
Match Blocks Charms NEW
Terms in this set (79)
https://quizlet.com/1196472209/nu-545-unit-4-exam-2026-questions-answers-with-verified-answers-latest-update-2026-update-compliance-tips-how-t… 1/56
,7/26/26, 9:18 AM NU 545 Unit 4 EXAM - 2026 (Questions + Answers) with verified Answers (Latest Update 2026) UPDATE!! Compliance Tips & How …
Infectious Mononucleosis (IM) p. 945 A benign, acute, self-limiting lymphoproliferative
clinical syndrome characterized by acute viral
infection of B lymphocytes (B cells). Associated with
several tumors, such as B cell and T cell, Hodgkin
lymphoma (HL) and nasopharyngeal carcinoma.
Linked to post-transplant lymphoproliferative diseases
(PTLD) and gastric carcinoma. Most common cause-
EBV (herpes virus). 90% of people have antibodies,
early infections rarely develop into IM. During
adolescence or later 35-50% get IM (p945).
Transmission of EBV: Saliva (Kissing Disease),
secretions of genital, rectal, resp tract & blood,
cervical and seminal fluid.. No aerosol transmission.
Disease begins with widespread infection of B
lymphocytes which have receptors for EBV. Virus
initially infects oropharynx, nasopharynx, and salivary
epithelial cells then spreads to lymphoid tissue and B
cells. Infection of B cells allows the virus to enter the
bloodstream, then the virus spreads systemically
(p946)
Patho of Infectious Mononucleosis p. Immunodeficiency, infected B cells may be
946 uncontrolled and lead to B-cell lymphoma. In the
immunocompetent patient, unaffected B cells
produce antibodies (IgG, IgM, IgA) against the virus.
There is a massive activation of proliferation of
cytotoxic T cells (CD8) directed against EBV infected
cells. Immune response against EBV is largely
responsible for cellular proliferation in the lymphoid
tissue (lymph nodes, spleen, tonsils, liver). Sore throat
and fever are the earliest manifestations d/t
inflammation at the site of viral entry and initial
infection, usually the mouth and throat.
https://quizlet.com/1196472209/nu-545-unit-4-exam-2026-questions-answers-with-verified-answers-latest-update-2026-update-compliance-tips-how-t… 2/56
,7/26/26, 9:18 AM NU 545 Unit 4 EXAM - 2026 (Questions + Answers) with verified Answers (Latest Update 2026) UPDATE!! Compliance Tips & How …
Clinical manifestations of infectious Pharyngitis (sore throat), lymphadenopathy, and fever
mononucleosis p. 946 (p945). Incubation period: 30-50 days (4-8 weeks),
then a 3-5 day prodrome of HA, fever, malaise,
arthralgias ( joint pain). cervical lymph nodes.
Pharyngitis: whitish, greyish green thick exudate.
Severe complications: meningitis, encephalitis, guillain
barre syndrome, bells palsy, optic neuritis, mental
impairment, transverse myelitis, cerebellar ataxia,
demyelinating disease.
Ocular manifestations: eyelid/periorbital edema, dry
eyes, keratitis, uveitis, conjunctivitis, retinitis,
oculoglandular syndrome, choroiditis, papillitis,
ophthalmoplegia.
In child: Reye syndrome.
Pulmonary involvement: RARE- hilar and mediastinal
lymphadenopathy, interstitial pneumonitis, pleural
effusions, pneumonia and resp fail in
immunocompromised patient. Older patient with 2
weeks of temp that can't be explained EBV should be
suspected, Most common cause of death is splenic
rupture (rare, 0.1-0.5%) r/t mild trauma in men <25
between 4 and 21 days after symptoms. Other deaths:
hepatic failure, bacterial infection, viral myocarditis.
https://quizlet.com/1196472209/nu-545-unit-4-exam-2026-questions-answers-with-verified-answers-latest-update-2026-update-compliance-tips-how-t… 3/56
, 7/26/26, 9:18 AM NU 545 Unit 4 EXAM - 2026 (Questions + Answers) with verified Answers (Latest Update 2026) UPDATE!! Compliance Tips & How …
Eval and Tx of infectious Children present w/: fever, pharyngitis (sore throat),
mononucleosis p. 947 lymphadenitis.
Young adults present w/: malaise, fatigue,
lymphadenopathy and fever of unknown origin.
Palatal petechiae (redish-brown spots on roof of
mouth), splenomegaly, and posterior cervical
adenopathy (lymphnodes).
Blood contains increased WBC (lymphocytes).
Dx based on Hoagland's criteria: 50% lymphocytes,
10% atypical lymphocytes in the blood with positive
heterophile antibody (IgM) with Monospot test.
presence of fever, pharyngitis, adenopathy confirmed
by a + serologic test. Serological test: heterophile
antibodies,
Monospot test (limited b/c CMV, adenovirus,
toxoplasmosis also produce heterophilic antibodies
causing false +).
Tx: IM is usually self limiting and intervention is rarely
required. Rest & alleviation of symptoms. No ASA used
with child or adolescent d/t reye syndrome.
Streptococcal pharyngitis (20-30% cases) tx w/ PCN
or erythromycin. NO ampicillin (causes rash in patients
with IM). Avoid strenuous activities. Steroids only with
severe complications (airway obstruction). Acyclovir
with immunocompromised pts.
https://quizlet.com/1196472209/nu-545-unit-4-exam-2026-questions-answers-with-verified-answers-latest-update-2026-update-compliance-tips-how-t… 4/56
