Dermatology NUR 611 1 - EXAM 1 - REVIEWER
Skin and Soft Tissue Infections: (SSTI)
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● 2 most common bacteria that cause skin infections: S. Aureus & S. pyogenes
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○ Gram (+) - Staph - most common - can cause MRSA
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○ Gram (-) - present in wound infections caused by:
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■ animal bites tf
■ trauma or surgery tf tf
■ exposed to infected water (E.coli, pseudomonas aeruginosa, proteus tf tf tf tf tf tf tf tf
mirabilis)
● Skin infections can be non-purulent or purulent
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Folliculitis, Furuncle, Carbuncle
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● Most commonly caused by S. Aureus - MRSA
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● Common in athletes, shaving, waxing, hot tubs
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● Occurs in areas with coarse hair
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➔ Presentation:
◆ Pustules in hair shaft tf tf tf
◆ Tenderness and redness tf tf
◆ If recurrent - ask if pt has DM
tf tf tf tf tf tf tf
◆ No diagnostics/labs needed - usually
tf tf tf tf
● If recurrent furuncles and carbuncles tf tf tf tf
○ Culture
● If MRSA suspected tf tf
○ Culture nares and axilla tf tf tf
➔ Treatments:
◆ Hygiene
◆ Warm, moist compress tf tf
◆ Betadine/Hibiclens wash (Antiseptic wash) tf tf tf
➔ Treatment for Folliculitis tf tf
◆ Benzoyl Peroxide 5%, Bactroban TID tf tf tf tf
◆ Clindamycin gel tf
➔ Treatment for Purulent SSTI tf tf tf
◆ 1st line - Incision & Drainage (I&D)
tf tf tf tf tf tf
◆ C&S
, ➔ Treatments for Furuncle and Carbuncle (PO)
tf tf tf tf tf
◆ Keflex 500mg (Cephalosporin 1st Gen) q12 x 10-14 days
tf tf tf tf tf tf tf tf
◆ MRSA
● Bactrim DS OD (Sulfonamide) x 10 -14 days tf tf tf tf tf tf tf
● Clindamycin 300 mg q6h x 14 days tf tf tf tf tf tf
Cellulitis
● Most caused by MRSA, Strep, H. Flu
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● Differential DX:
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○ Gout
○ Dermatitis
○ Herpes Zoster tf
➔ Presentation:
◆ Erythema
◆ Warmth
◆ Pain
◆ Lymphedema
◆ Fissuring
◆ Abscess
➔ Diagnostic test/Labs:
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◆ C&S
◆ CBC (Leukocytosis)
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◆ Blood CX, ESR tf tf
◆ Imaging to r/o OM tf tf tf
➔ Management:
◆ Hygiene, elevation, moist heat tf tf tf
◆ Pharma:
● Uncomplicated/nonsystematic:
○ PCN 500 mg q6 tf tf tf
○ Keflex 500 mg q12 x 10-14 days tf tf tf tf tf tf
◆ IDSA - rx min 5 days, extend if no improvement tf tf tf tf tf tf tf tf tf
○ MRSA:
◆ Bactrim DS OD x 10-14 days tf tf tf tf tf
◆ Clindamycin 300 mg q6h tf tf tf
, ◆ Pt w/ comorbidity: DM/HF
tf tf tf
● Non-ulcer
○ Amoxicillin/Clavulanate 500 mg q12h x 7-10 days tf tf tf tf tf tf
○ Quinolone - Cipro 500-750 mg q12h x 7-14 days tf tf tf tf tf tf tf tf
◆ Gram (-) and anaerobic coverage tf tf tf tf
● Mild ulcer tf
○ Cipro + Clindamycin tf tf
◆ Follow up: 48 HOURS!!! tf tf tf
➔ Refer to ID /Hospitalize pts if:
tf tf tf tf tf
◆ Immunocompromised pt = HOSPITAL ALWAYS! tf tf tf tf
◆ S/s of toxicity tf tf
● T >100.5 tf
● Hypotension
● Sustained tachycardia tf
◆ Rapid progression of erythema tf tf tf
◆ Rapid progression of clinical findings after 48hrs of antibx tx
tf tf tf tf tf tf tf tf tf
◆ Inability to tolerate oral therapy tf tf tf tf
◆ Proximity of the lesion to an indwelling medical device (prostethic jt or v
tf tf tf tf tf tf tf tf tf tf tf tf
ascular graft) tf
◆ Periorbital cellulitis = INPATIENT TX/ REFER ALWAYS! tf tf tf tf tf tf
◆ Refer to ID: hand infection, infection from bites (consider admission)
tf tf tf tf tf tf tf tf tf
Dermatitis:
● Contact Dermatitis
tf
○ Allergic
■ Causes: Nickel (jewelry), medications (topical cream/ointments), poison tf tf tf tf tf tf tf
oaks, personal products tf tf
■ Location: exposed areas, usually hands tf tf tf tf
■ Symptoms: predominantly pruritus tf tf
■ Surface appearance: vesicles and bullae tf tf tf tf
■ Lesion borders: distinct angles, line, and borders tf tf tf tf tf tf
○ Irritant
■ Causes: solvents, bleach, alcohol, chemicals in personal products tf tf tf tf tf tf tf
■ Location: usually hands tf tf
■ Symptoms: burning, pruritus, pain tf tf tf
■ Surface appearance: dry fissured skin tf tf tf tf
■ Lesion borders: less distinct tf tf tf
Skin and Soft Tissue Infections: (SSTI)
tf tf tf tf tf
● 2 most common bacteria that cause skin infections: S. Aureus & S. pyogenes
tf tf tf tf tf tf tf tf tf tf tf tf
○ Gram (+) - Staph - most common - can cause MRSA
tf tf tf tf tf tf tf tf tf tf
○ Gram (-) - present in wound infections caused by:
tf tf tf tf tf tf tf tf
■ animal bites tf
■ trauma or surgery tf tf
■ exposed to infected water (E.coli, pseudomonas aeruginosa, proteus tf tf tf tf tf tf tf tf
mirabilis)
● Skin infections can be non-purulent or purulent
tf tf tf tf tf tf
Folliculitis, Furuncle, Carbuncle
tf tf
● Most commonly caused by S. Aureus - MRSA
tf tf tf tf tf tf tf
● Common in athletes, shaving, waxing, hot tubs
tf tf tf tf tf tf
● Occurs in areas with coarse hair
tf tf tf tf tf
➔ Presentation:
◆ Pustules in hair shaft tf tf tf
◆ Tenderness and redness tf tf
◆ If recurrent - ask if pt has DM
tf tf tf tf tf tf tf
◆ No diagnostics/labs needed - usually
tf tf tf tf
● If recurrent furuncles and carbuncles tf tf tf tf
○ Culture
● If MRSA suspected tf tf
○ Culture nares and axilla tf tf tf
➔ Treatments:
◆ Hygiene
◆ Warm, moist compress tf tf
◆ Betadine/Hibiclens wash (Antiseptic wash) tf tf tf
➔ Treatment for Folliculitis tf tf
◆ Benzoyl Peroxide 5%, Bactroban TID tf tf tf tf
◆ Clindamycin gel tf
➔ Treatment for Purulent SSTI tf tf tf
◆ 1st line - Incision & Drainage (I&D)
tf tf tf tf tf tf
◆ C&S
, ➔ Treatments for Furuncle and Carbuncle (PO)
tf tf tf tf tf
◆ Keflex 500mg (Cephalosporin 1st Gen) q12 x 10-14 days
tf tf tf tf tf tf tf tf
◆ MRSA
● Bactrim DS OD (Sulfonamide) x 10 -14 days tf tf tf tf tf tf tf
● Clindamycin 300 mg q6h x 14 days tf tf tf tf tf tf
Cellulitis
● Most caused by MRSA, Strep, H. Flu
tf tf tf tf tf tf
● Differential DX:
tf
○ Gout
○ Dermatitis
○ Herpes Zoster tf
➔ Presentation:
◆ Erythema
◆ Warmth
◆ Pain
◆ Lymphedema
◆ Fissuring
◆ Abscess
➔ Diagnostic test/Labs:
tf
◆ C&S
◆ CBC (Leukocytosis)
tf
◆ Blood CX, ESR tf tf
◆ Imaging to r/o OM tf tf tf
➔ Management:
◆ Hygiene, elevation, moist heat tf tf tf
◆ Pharma:
● Uncomplicated/nonsystematic:
○ PCN 500 mg q6 tf tf tf
○ Keflex 500 mg q12 x 10-14 days tf tf tf tf tf tf
◆ IDSA - rx min 5 days, extend if no improvement tf tf tf tf tf tf tf tf tf
○ MRSA:
◆ Bactrim DS OD x 10-14 days tf tf tf tf tf
◆ Clindamycin 300 mg q6h tf tf tf
, ◆ Pt w/ comorbidity: DM/HF
tf tf tf
● Non-ulcer
○ Amoxicillin/Clavulanate 500 mg q12h x 7-10 days tf tf tf tf tf tf
○ Quinolone - Cipro 500-750 mg q12h x 7-14 days tf tf tf tf tf tf tf tf
◆ Gram (-) and anaerobic coverage tf tf tf tf
● Mild ulcer tf
○ Cipro + Clindamycin tf tf
◆ Follow up: 48 HOURS!!! tf tf tf
➔ Refer to ID /Hospitalize pts if:
tf tf tf tf tf
◆ Immunocompromised pt = HOSPITAL ALWAYS! tf tf tf tf
◆ S/s of toxicity tf tf
● T >100.5 tf
● Hypotension
● Sustained tachycardia tf
◆ Rapid progression of erythema tf tf tf
◆ Rapid progression of clinical findings after 48hrs of antibx tx
tf tf tf tf tf tf tf tf tf
◆ Inability to tolerate oral therapy tf tf tf tf
◆ Proximity of the lesion to an indwelling medical device (prostethic jt or v
tf tf tf tf tf tf tf tf tf tf tf tf
ascular graft) tf
◆ Periorbital cellulitis = INPATIENT TX/ REFER ALWAYS! tf tf tf tf tf tf
◆ Refer to ID: hand infection, infection from bites (consider admission)
tf tf tf tf tf tf tf tf tf
Dermatitis:
● Contact Dermatitis
tf
○ Allergic
■ Causes: Nickel (jewelry), medications (topical cream/ointments), poison tf tf tf tf tf tf tf
oaks, personal products tf tf
■ Location: exposed areas, usually hands tf tf tf tf
■ Symptoms: predominantly pruritus tf tf
■ Surface appearance: vesicles and bullae tf tf tf tf
■ Lesion borders: distinct angles, line, and borders tf tf tf tf tf tf
○ Irritant
■ Causes: solvents, bleach, alcohol, chemicals in personal products tf tf tf tf tf tf tf
■ Location: usually hands tf tf
■ Symptoms: burning, pruritus, pain tf tf tf
■ Surface appearance: dry fissured skin tf tf tf tf
■ Lesion borders: less distinct tf tf tf