Questions and Correct
Answers | New Update
What is the Blood-Brain Barrier (BBB)? - ANSWER ✔✔A selective
barrier that restricts drug entry into the central nervous system.
How does the BBB affect drug sensitivity in neonates and infants? -
ANSWER ✔✔The immature BBB leads to increased CNS drug
sensitivity, requiring lower doses and careful monitoring.
What is the primary consideration when selecting drugs for general CNS
disorders? - ANSWER ✔✔Choose drugs that can cross the BBB.
, What neurotransmitter is primarily involved in Parkinson's disease? -
ANSWER ✔✔Dopamine.
What neurotransmitter is primarily involved in Alzheimer's disease? -
ANSWER ✔✔Acetylcholine
What is the main treatment for Parkinson's disease? - ANSWER
✔✔Levodopa, often combined with carbidopa.
What are MAO-B inhibitors used for in Parkinson's disease? -
ANSWER ✔✔They provide mild benefits and are the treatment of
choice for mild symptoms.
What are common side effects of dopamine agonists? - ANSWER
✔✔Nausea, dizziness, daytime somnolence, insomnia, constipation,
weakness, and hallucinations.
What is the mechanism of action of levodopa? - ANSWER ✔✔It
increases dopamine synthesis in the striatum by entering the brain and
converting to dopamine.
What is a significant adverse effect of long-term levodopa treatment? -
ANSWER ✔✔Dyskinesias, which may be disabling.