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CMN 574 UNIT 3 ADHD/Eating Disorders/Child & Elder Abuse/Substance Abuse/CHD EXAM.

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Most common congenital heart malformation VSD Window for spontaneous closure of PDA Up to age 1 year. Spontaneous closure after that age is rare. Leading cause of HF in 1st month of life Coarctation of aorta - either alone or in combination with ASD, VSD or other cardiac anomalies. Syndrome commonly seen in female patients with coarctation of the aorta? Turner's Syndrome Features of tetralogy of fallot 1) Pulmonary stenosis 2) RV hypertrophy 3) Overriding aorta 4) VSD Presentation of tetralogy of fallot + Hypoxemic spells during infancy ("Tet spells", around 4 - 6 months) + Cyanosis at birth or by 4 months + Clubbing of fingers and toes + Elevated H&H and RBC due to chronic arterial desaturation NOTE: 2 dimensional imaging is diagnostic What is the leading cause of acquired heart disease in children in the US? Kawasaki disease. Diagnostic criteria for Kawasaki disease High fever for at least 5 days, plus 4 of 5: - changes in oral mucosa - extremity changes (redness/swelling/desquamation) - unilateral cervical lymphadenopathy (least likely to be present) - rash - bilateral, non-exudative conjunctivitis Median age of diagnosis for Kawasaki disease + 80% are younger than 5 yrs + Median age is 2 yrs Treatment of Kawasaki Disease IVIG, high-dose aspirin Most common causes of pericarditis in children VIRAL infections (e.g. coxsackievirus, mumps, epstein-barr, adenovirus, influenza and HIV) Presentation of pericarditis in children + Sharp, stabbing chest/shoulder/neck pain made worse by deep inspiration and decreased by leaning forward Most common cause of chest pain in children inflammation of musculoskeletal structures of chest wall. When would you suspect bacterial endocarditis in a child with congenital heart disease? Prolonged fever without a known cause Diagnostic criteria for rheumatic fever? Two major OR one major and two minor: MAJOR + Carditis + Polyarthritis + Cydenham chorea + Erythema marginatum + Subcutaneous nodules MINOR + Clinical -- Previous rheumatic fever or rheumatic heart dz, polyarthralgia, fever + Lab - ↑ ESR, CRP, leukocytosis; prolonged PR interval; PLUS evidence of previous strep infection. What gradient BP difference Between upper and lower extremities would make you suspect coaction of the aorta? ≥ 20 mm/Hg higher in UPPER extremities What can be used to close a PDA? Indomethacin Heart defect associated with split s2? Where is it heard? ASD, heard at LL sternal border ______ age group has a dull thick hymen; ______ age group will have thin, reddened, sensitive vaginal mucosa Newborn -- dull and thick Pre-pubertal -- thin, reddened, sensitive What's the best position to perform a pediatric rectal exam? Supine knee chest What are the treatment options for labial fusion? If it's mild there is no treatment. You might have to treat for a UTI though. -Otherwise, premarin cream According to Korn: what's the ideal amount of time to collect evidence after sexual assault? 72 hours Most common bacterial organism and treatment recommendations for vulvovaginitis? Organism: GABHS -Tx: Pen VK, bactroban (plus topical nystatin if candidiasis present) BED pt with Hx of serotonin syndrome on Prozac as a teenager. What could you rx to encourage binge remission? Topamax BED pt with Hx of serotonin syndrome on Prozac as a teenager. What could you rx to encourage binge remission? Topamax Anogenital molluscum contagiosum in children + Not related to sexual contact, but associated with swimming pool use, skin to skin contact, sharing of fomites + Small, single or multiple umbilicated papules (2 - 4 mm) with a white, waxy core. Factors that increase concern for sexual abuse as factor in perineal straddle injury sx 1) No hx of injury 2) 9 months or non-ambulatory 3) Perineal, vaginal or hymenal injury without hx of penetrating trauma 4) Extensive or severe trauma 5) Presence of non-urogenital trauma 6) HIPF Tx of urethral prolapse Sitz baths or estrogen cream Presentation of a small VSD + Small hole - Turbulence - LOUD murmur (+ thrill sometimes) + Shape = Holosystolic 3 causes of holosystolic murmur + Mitral regurgitation + Tricuspid regurgitation + Ventricular septal defect -NOTE: Only the VSD patient will not be SICK when you hear the murmur. Quality of a PDA + CONTINUOUS machine-like murmur + Heard in both systole AND diastole, which distinguishes it from other murmurs which are only in one part of the cycle. You rx a stimulant to a 10 yo boy for ADHD after neuropsych w/u. What are you monitoring on him at each visit? SATA a) HR & BP, b) vision & hearing, c) weight & height, d) all of the above, e) a & c. VSD is a congenital defect most commonly associated with: a) Down syndrome, b) Fetal etoh syndrome, c) gestational DM, d) congenital rubella. PDA is a defect most commonly associated with: a) Down syndrome, b) Fetal etoh syndrome, c) gestational DM, d) congenital rubella. ASD is a heart defect most commonly associated with: a) Down syndrome, b) Fetal etoh syndrome, c) gestational DM, d) congenital rubella. Which heart condition is oft associated with Turner's? a) PDA, b.) tricuspid atresia, c) truncus arteriosus, d) tet of fallot. Which of the following are NOT part of the dx criteria for anorexia nervosa? a) intense fear of wt gain, b) significantly low weight, c) severe body image disturbance, d) absence of menstrual cycle. A pt who abuses alcohol with probably exhibit: a) elevated alkaline phosphatase, b) decreased TSH, c) elevated ALT, AST, and GGT, d) elevated AST only. Which of the following is true about elder abuse and neglect? (SATA) a) it is always physical, b) the elder will always be willing to tell the provider what is happening, c) it can be financial, physical, or emotional, d) is a contributor to poor nutritional status, e) is suspected if the "story" does not fit the injury or concern. Which of the following ADHD meds are not classified as an amphetamine/stimulant? a) dexmethylphenidate, b) mixed salts of amphetamine, c) methylphenidate, d) atomoxetine.

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CMN 574 UNIT 3 EXAM
3 parts of the neurodevelopmental evaluation
1) Defining developmental level in multiple domains (e.g. language, motor, visual-
spatial, attention and social)
2) Determining etiology of developmental delays
3) Planning a tx program




3 VERY EARLY components of child's medical history to identify conditions that
might compromise CNS function
1) Pregnancy
2) Labor
3) Delivery


Examples of dysmorphic features to make note of in the neurodevelopmental
examination
+ Epicanthal folds
+ Palpebral fissure size
+ Shape and length of philtrum
+ Low set or posteriorly rotated ears
+ Prominent ear pinnae
+ Unusual dermatoglyphics (e.g. single transverse palmar crease)

,+ Hyperextensibility of joints
+ Syndactyly or clinodactyly


Diagnostic criteria for ADHD in children
+ ≥ 6 symptoms of inattention or hyperactivity/impulsivity persisting for ≥ 6 months
which is maladaptive AND inconsistent with developmental level:
+ Onset is ≤ 12 y.o.
+ Several sx are present in 2 or more settings (e.g. home, school, work; with friends or
relatives; in other activities)
+ Evidence that sx causes distress or impairment of social, academic or
occupational functioning
+ Do not exclusively occur during course of a psychotic disorder, and are not better
explained by another mental disorder




Differences in diagnostic criteria for ADHD in children with ASD?
For children > 17 and adults with ASD, only 5 symptoms from the "Inattention" or
"Impulsivity/Hyperactivity" domains are required.


With regard to ADHD dx, girls have a ↑ prevalence of the _______ type and boys
have a ↑ prevalence of the ______ type.
Girls = Inattentive
Boys = Hyperactive

,SELECT ALL THAT APPLY: Which features of ADHD often persist into adolescence
and adulthood?
a) Hyperactivity
b) Impulsivity
c) Inattentiveness
B, C




Relationship between Tourette's and ADHD?
+ Up to 25% of kids with ADHD have Tourette's
+ Over 50% of kids with Tourette's have ADHD




What genetic disorders are also associated with ADHD?
+ Fragile X
+ Williams Syndrome
+ Angelman Syndrome
+ Kleinfelter Syndrome
+ Turner Syndrome




True/False: Hyperthyroidism can sometimes cause ADHD?

, TRUE




Extended-release stimulant medications for ADHD
+ Methylphenidate (Ritalin LA or SR, Concerta, Quillivant SR, Daytrana patch,
Contempla ODT)
+ Dexmethylphenidate (Focalin XR)
+ Detroamphetamine (Dexedrine CR)
+ Mixed amphetamine (Adderall XR, Mydayis)
+ Lisdexamfetamine (Vyvanse)




Examples of non-stimulant medications for ADHD
SNRI
+ Atomoxetine (Strattera)
--- 2nd line med (per Hay) or as an adjunct to stimulants.
---LOW ABUSE POTENTIAL
---Good for comorbid tic, anxiety or substance abuse disorder
---Effect not seen for 2 - 4 weeks!


α-adrenergic agonists
+ Clonidine (Kapvay XR) --

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