NURSl 5434/l NURS5434l Finall Examl
(NEWl 2026l Update)l –l Familyl IIIl (FNPl
3)l Guidel |l Questionsl &l Answersl |l Gradel
A|l 100%l Correctl (Verifiedl Solutions)-l
UTA
QUESTION
statinl dosingl basedl onl ASCVDl percentage
Answer:
<5%l -l lifestylel mods
5-7.5%l -l lifestyle,l considerl statinl ifl riskl enhancers
7.5-20%l -l moderatel intensityl statin
>20%l -l highl intensityl statinl
CACl scoresl canl helpl decidel inl borderlinel casesl (CACl >100l startl al statin)
QUESTION
Highl Intensityl Statin
Answer:
atorvastatinl 40-80l mg
rosuvastatinl 20-40l mg
reducesl LDLl >50%
QUESTION
Moderatel Intensityl Statin
Answer:
,atorvastatinl 10-20mg
rosuvastatinl 5-10mg
simvastatinl 20-40mg
pravastatinl 40-80mg
reducesl LDLl 30-49%
QUESTION
Lowl intensityl statin
Answer:
simvastatinl 10mg
pravastatinl 10-20mg
reducesl LDLl <30%
QUESTION
whenl tol addl ezetimibe
Answer:
-l patientsl withl clinicall ASCVDl whol arel alreadyl onl maximuml statinl therapyl andl LDLl
>70l orl ifl needl >50%l dropl
-l patientsl withl LDLl >190l atl baselinel orl withl LDL>100l onl maxl statinl
whyl addl ezetimibel first?
-l welll tolerated,l inezpensive,l lowersl LDLl 20-25%
QUESTION
whenl tol addl PCSK9
Answer:
-l ptsl withl clinicall ASCVDl atl veryl highl riskl whol arel onl maxl statinl therapyl andl
ezetimibel butl stilll havel LDLl >70l
-l ptl withl familiall hypercholesterolemial (LDL>190)l andl stilll >100l onl maxl statinl andl
ezetimibe
,QUESTION
PCSK9l Inhibitors
Answer:
alirocumab,l evolocumab
injectiblel andl expensive
decreasel LDLl ~60%
savedl forl highestl riskl people
QUESTION
whatl countsl asl "veryl highl riskl ASCVD"
Answer:
multiplel majorl ASCVDl eventsl (MI,l stroke,l PAD)l ORl 1l majorl ASCVDl eventl andl
multiplel highl riskl conditionsl likel DM,l HTN,l smoking,l CKD,l agel >65
recentl ACSl withinl lastl year,l Hxl MIl orl stroke,l symptomaticl PAD,l ABIl <8.5,l previousl
revascularizationl orl amputation
QUESTION
Statinl Sidel Effects
Answer:
Mostl commonl -l musclel aches,l cramps,l weaknessl
Rhabdomyolysisl isl rarel -l darkl urine,l markedl CKl elevationl
Liverl impactl -l statinsl canl causel transientl increasel inl ALT/AST,l onlyl monitorl LFTsl ifl
symptomatic
QUESTION
CACl Scoring
Answer:
Coronaryl Calciuml Screeningl
, CTl withoutl contrastl thatl measuresl thel amountl andl locationl ofl calcifiedl coronaryl arteryl
plaquel (doesn'tl measurel softl plaquel whichl isl thel kindl mostl likelyl tol rupture)
-l providesl strongl evidencel ofl riskl
0l -l nol evidencel ofl CAD
1-10l -l minimall evidence
11-100l mildl evidence,l lookl atl riskl factors
101-400l moderatel evidencel ofl CAD
>400l extensivel evidencel ofl CAD
QUESTION
Howl tol managel myalgias
Answer:
1.l stopl statinl forl 2-4l weeksl tol seel ifl sxl resolve
2.l checkl CK,l TSH,l vitaminl D,l renall functionl
3.l ifl sxl resolve,l startl atl lowerl dosel orl tryl differentl statinl (pravastatinl andl rosuvastatinl
arel LESSl lipophillic)
4.l considerl alternatel dayl dosing
5.l ifl intolerablel despitel tryingl 2-3l statins,l considerl ezetimibel orl PCSK9l inhibitorsl ifl
highl risk
QUESTION
Statinl Followl Up
Answer:
Repeatl lipidl testingl inl 4-12l weeksl afterl tol monitorl adherencel andl biologicall response
Thenl checkl everyl 3-12l monthsl froml there
CKl andl ALTl notl necessaryl unlessl symptomatic
QUESTION
Pediatricl Lipidl Screening
Answer:
Agel 9-11l andl 17-21
(NEWl 2026l Update)l –l Familyl IIIl (FNPl
3)l Guidel |l Questionsl &l Answersl |l Gradel
A|l 100%l Correctl (Verifiedl Solutions)-l
UTA
QUESTION
statinl dosingl basedl onl ASCVDl percentage
Answer:
<5%l -l lifestylel mods
5-7.5%l -l lifestyle,l considerl statinl ifl riskl enhancers
7.5-20%l -l moderatel intensityl statin
>20%l -l highl intensityl statinl
CACl scoresl canl helpl decidel inl borderlinel casesl (CACl >100l startl al statin)
QUESTION
Highl Intensityl Statin
Answer:
atorvastatinl 40-80l mg
rosuvastatinl 20-40l mg
reducesl LDLl >50%
QUESTION
Moderatel Intensityl Statin
Answer:
,atorvastatinl 10-20mg
rosuvastatinl 5-10mg
simvastatinl 20-40mg
pravastatinl 40-80mg
reducesl LDLl 30-49%
QUESTION
Lowl intensityl statin
Answer:
simvastatinl 10mg
pravastatinl 10-20mg
reducesl LDLl <30%
QUESTION
whenl tol addl ezetimibe
Answer:
-l patientsl withl clinicall ASCVDl whol arel alreadyl onl maximuml statinl therapyl andl LDLl
>70l orl ifl needl >50%l dropl
-l patientsl withl LDLl >190l atl baselinel orl withl LDL>100l onl maxl statinl
whyl addl ezetimibel first?
-l welll tolerated,l inezpensive,l lowersl LDLl 20-25%
QUESTION
whenl tol addl PCSK9
Answer:
-l ptsl withl clinicall ASCVDl atl veryl highl riskl whol arel onl maxl statinl therapyl andl
ezetimibel butl stilll havel LDLl >70l
-l ptl withl familiall hypercholesterolemial (LDL>190)l andl stilll >100l onl maxl statinl andl
ezetimibe
,QUESTION
PCSK9l Inhibitors
Answer:
alirocumab,l evolocumab
injectiblel andl expensive
decreasel LDLl ~60%
savedl forl highestl riskl people
QUESTION
whatl countsl asl "veryl highl riskl ASCVD"
Answer:
multiplel majorl ASCVDl eventsl (MI,l stroke,l PAD)l ORl 1l majorl ASCVDl eventl andl
multiplel highl riskl conditionsl likel DM,l HTN,l smoking,l CKD,l agel >65
recentl ACSl withinl lastl year,l Hxl MIl orl stroke,l symptomaticl PAD,l ABIl <8.5,l previousl
revascularizationl orl amputation
QUESTION
Statinl Sidel Effects
Answer:
Mostl commonl -l musclel aches,l cramps,l weaknessl
Rhabdomyolysisl isl rarel -l darkl urine,l markedl CKl elevationl
Liverl impactl -l statinsl canl causel transientl increasel inl ALT/AST,l onlyl monitorl LFTsl ifl
symptomatic
QUESTION
CACl Scoring
Answer:
Coronaryl Calciuml Screeningl
, CTl withoutl contrastl thatl measuresl thel amountl andl locationl ofl calcifiedl coronaryl arteryl
plaquel (doesn'tl measurel softl plaquel whichl isl thel kindl mostl likelyl tol rupture)
-l providesl strongl evidencel ofl riskl
0l -l nol evidencel ofl CAD
1-10l -l minimall evidence
11-100l mildl evidence,l lookl atl riskl factors
101-400l moderatel evidencel ofl CAD
>400l extensivel evidencel ofl CAD
QUESTION
Howl tol managel myalgias
Answer:
1.l stopl statinl forl 2-4l weeksl tol seel ifl sxl resolve
2.l checkl CK,l TSH,l vitaminl D,l renall functionl
3.l ifl sxl resolve,l startl atl lowerl dosel orl tryl differentl statinl (pravastatinl andl rosuvastatinl
arel LESSl lipophillic)
4.l considerl alternatel dayl dosing
5.l ifl intolerablel despitel tryingl 2-3l statins,l considerl ezetimibel orl PCSK9l inhibitorsl ifl
highl risk
QUESTION
Statinl Followl Up
Answer:
Repeatl lipidl testingl inl 4-12l weeksl afterl tol monitorl adherencel andl biologicall response
Thenl checkl everyl 3-12l monthsl froml there
CKl andl ALTl notl necessaryl unlessl symptomatic
QUESTION
Pediatricl Lipidl Screening
Answer:
Agel 9-11l andl 17-21