NURS 5334/ NURS5334 Final Exam
(NEW 2026 Update) – Advanced
Pharmacology Guide | Questions &
Answers | Grade A| 100% Correct
(Verified Solutions)- UTA
QUESTION
Levothyroxine
Answer:
ol T4
ol Longl halfl life
ol Howl shouldl thisl bel taken?
l Inl thel morning,l atl leastl 30l tol 60l minutesl beforel breakfast
ol Sidel effects—tachycardia,l anginal tremors
ol Drug/Drug
l Warfarin—intensifyl effects
l Drugsl thatl reducel absorption
l H2l receptorl blockers,l PPIs,l cholestyramine,l colestipol,l Maalox,l Mylanta,
calciuml supplements,l iron,l magnesium,l orlistat
l Acceleratel metabolism
l Phenytoin,l carbamazepine,l rifampin,l sertraline,l phenobarbital
l Catecholamines—increasel cardiacl responses
l Increasel requirementsl ofl insulinl andl digoxin
QUESTION
Howl isl thisl dosed?l Howl doesl dosagel differl forl someonel overl 50?l 65l andl older?
Someonel withl heartl disease?l Overweight?l Underweight?
Answer:
1.6-1.8l mcg/kg/day
l Obese—gol byl ideall bodyl weight
l Underweight—actuall weight
l Olderl patientsl withl CAD—startl withl 12.5-25l mcg
l Elderly—startl lowl andl gol slow
,l Youngerl thanl 3l months—10l tol 15l mcg/kg/day
l Childrenl (3-5l months)—8l tol 10l mcg/kg/day
l Childrenl (6-11l months)—6l tol 8l mcg/kg/day
l Childrenl 1-5l years—5l tol 6l mcg/kg/day
l Childrenl 6-12—4l tol 5l mcg/kg/day
QUESTION
Liotrix—al mixturel ofl syntheticl T4l plusl syntheticl T3l inl al 4:1l fixedl ratio
Answer:
ol Becausel levothyroxinel alonel producesl thel samel ratiol ofl T4l tol T3,l Liotrixl offersl no
advantagel overl levothyroxinel forl mostl indications
QUESTION
Armour—consistsl ofl desiccatedl animall thyroidl glands.
Answer:
ol Standardizationl isl basedl onl contentl ofl iodine,l levothyroxine,l andl liothyronine.
ol Thel ratiol ofl levothyroxinel tol lipthyroninel isl notl lessl thanl 5:1
ol Thyroidl isl availablel inl tabletsl (15-300l mg)
QUESTION
Methimazole—usedl inl hyperthyroidism
Answer:
ol Celll forml ofl therapyl forl Graves'l disease
ol Adjunctl tol radiationl therapyl untill thel effectsl ofl radiationl becomel manifested
ol Suppressesl thel thyroidl hormonel synthesisl inl preparationl forl thyroidl glandl surgery
ol Thyrotoxicl crisis
QUESTION
Propylthiouracil
Answer:
,ol Inhibitsl thyroidl hormonel synthesis
ol Secondl linel forl graves
ol Shortl half-life
ol Fulll benefits—6l tol 12l months
ol Uses—graves',l adjunctl therapyl tol radiation,l preparationl forl thyroidl glandl surgery,
thyrotoxicl crisis
ol Adversel effects—agranulocytosis,l severel liverl damage
ol Pregnancy?l Crossesl thel placental lessl andl concentrationsl inl breastmilkl arel lowerl than
methimazole
QUESTION
Radioactivel Iodinel 131l (lugoll solution)
Answer:
ol Effectl onl thel thyroidl isl destructionl ofl thyroidl tissuel byl emissionl ofl betal particles
ol Advantages—lowl cost;l sparedl thel risk,l discomfort,l andl experiencel ofl thyroidl surgery;
deathl isl extremelyl rare;l nol tissuel otherl thanl thyroidl isl injured
ol Disadvantages—treatmentl isl delated,l takingl severall monthsl tol becomel maximal;
treatmentl isl associatedl withl significantl incidentsl ofl delayedl hypothyroidisml from
destructionl ofl thyroidl tissuel (needl levothyroxine)
ol Diagnosticl uses?
l Hyperthyroidism,l hypothyroidism,l andl goiter
ol Pregnancy—contraindicated
QUESTION
ol Whatl arel indicationsl forl Lugoll solution?
~~~~~~~~~~~~~~~~~~~
ol Sidel effects?
l Brassyl taste,l burningl sensationl inl thel mouthl andl throat,l sorenessl ofl thel teeth
andl gums,l frontall headache,l coryza,l salvationl andl skinl eruptions
Answer:
Adultsl withl hyperthyroidism
l Patientsl whol havel notl respondedl adequatelyl tol anti-thyroidl drugsl orl subtotal
thyroidectomy
l Thyroidl cancer
~~~~~~~~~
, l Brassyl taste,l burningl sensationl inl thel mouthl andl throat,l sorenessl ofl thel teeth
andl gums,l frontall headache,l coryza,l salvationl andl skinl eruptions
QUESTION
Whatl arel stagesl ofl menstruall cycle?
Answer:
ol Follicularl phase
ol Luteall phase
ol Fulll cyclel aboutl 28l days
QUESTION
Whatl arel estrogenl effectsl onl primaryl andl secondaryl sexl characteristics?
Answer:
ol Influencel thel physiologicl processesl relatedl tol reproduction
ol Affectsl thel ductall growthl inl thel breasts,l thel thickeningl andl cornificationl ofl thel
vaginal
epithelium,l thel proliferationl ofl thel uterinel epithelium,l andl thel copiousl secretionl of
thickenedl mucusl forml thel endocervicall glands
QUESTION
Metabolicl effectsl ofl Estrogen?
Answer:
ol Positivel effectl onl bonel mass—blockl bonel resorption
ol Favorablel effectsl onl cholesteroll levels
l Decreasel LDL,l raisel HDL
ol Effectl onl bloodl coagulation
l Increasingl thel levelsl ofl thel coagulationl factors
ol Affectl glucosel homeostasis
l Increasel insulinl sensitivityl andl promotel glucosel uptake
QUESTION
(NEW 2026 Update) – Advanced
Pharmacology Guide | Questions &
Answers | Grade A| 100% Correct
(Verified Solutions)- UTA
QUESTION
Levothyroxine
Answer:
ol T4
ol Longl halfl life
ol Howl shouldl thisl bel taken?
l Inl thel morning,l atl leastl 30l tol 60l minutesl beforel breakfast
ol Sidel effects—tachycardia,l anginal tremors
ol Drug/Drug
l Warfarin—intensifyl effects
l Drugsl thatl reducel absorption
l H2l receptorl blockers,l PPIs,l cholestyramine,l colestipol,l Maalox,l Mylanta,
calciuml supplements,l iron,l magnesium,l orlistat
l Acceleratel metabolism
l Phenytoin,l carbamazepine,l rifampin,l sertraline,l phenobarbital
l Catecholamines—increasel cardiacl responses
l Increasel requirementsl ofl insulinl andl digoxin
QUESTION
Howl isl thisl dosed?l Howl doesl dosagel differl forl someonel overl 50?l 65l andl older?
Someonel withl heartl disease?l Overweight?l Underweight?
Answer:
1.6-1.8l mcg/kg/day
l Obese—gol byl ideall bodyl weight
l Underweight—actuall weight
l Olderl patientsl withl CAD—startl withl 12.5-25l mcg
l Elderly—startl lowl andl gol slow
,l Youngerl thanl 3l months—10l tol 15l mcg/kg/day
l Childrenl (3-5l months)—8l tol 10l mcg/kg/day
l Childrenl (6-11l months)—6l tol 8l mcg/kg/day
l Childrenl 1-5l years—5l tol 6l mcg/kg/day
l Childrenl 6-12—4l tol 5l mcg/kg/day
QUESTION
Liotrix—al mixturel ofl syntheticl T4l plusl syntheticl T3l inl al 4:1l fixedl ratio
Answer:
ol Becausel levothyroxinel alonel producesl thel samel ratiol ofl T4l tol T3,l Liotrixl offersl no
advantagel overl levothyroxinel forl mostl indications
QUESTION
Armour—consistsl ofl desiccatedl animall thyroidl glands.
Answer:
ol Standardizationl isl basedl onl contentl ofl iodine,l levothyroxine,l andl liothyronine.
ol Thel ratiol ofl levothyroxinel tol lipthyroninel isl notl lessl thanl 5:1
ol Thyroidl isl availablel inl tabletsl (15-300l mg)
QUESTION
Methimazole—usedl inl hyperthyroidism
Answer:
ol Celll forml ofl therapyl forl Graves'l disease
ol Adjunctl tol radiationl therapyl untill thel effectsl ofl radiationl becomel manifested
ol Suppressesl thel thyroidl hormonel synthesisl inl preparationl forl thyroidl glandl surgery
ol Thyrotoxicl crisis
QUESTION
Propylthiouracil
Answer:
,ol Inhibitsl thyroidl hormonel synthesis
ol Secondl linel forl graves
ol Shortl half-life
ol Fulll benefits—6l tol 12l months
ol Uses—graves',l adjunctl therapyl tol radiation,l preparationl forl thyroidl glandl surgery,
thyrotoxicl crisis
ol Adversel effects—agranulocytosis,l severel liverl damage
ol Pregnancy?l Crossesl thel placental lessl andl concentrationsl inl breastmilkl arel lowerl than
methimazole
QUESTION
Radioactivel Iodinel 131l (lugoll solution)
Answer:
ol Effectl onl thel thyroidl isl destructionl ofl thyroidl tissuel byl emissionl ofl betal particles
ol Advantages—lowl cost;l sparedl thel risk,l discomfort,l andl experiencel ofl thyroidl surgery;
deathl isl extremelyl rare;l nol tissuel otherl thanl thyroidl isl injured
ol Disadvantages—treatmentl isl delated,l takingl severall monthsl tol becomel maximal;
treatmentl isl associatedl withl significantl incidentsl ofl delayedl hypothyroidisml from
destructionl ofl thyroidl tissuel (needl levothyroxine)
ol Diagnosticl uses?
l Hyperthyroidism,l hypothyroidism,l andl goiter
ol Pregnancy—contraindicated
QUESTION
ol Whatl arel indicationsl forl Lugoll solution?
~~~~~~~~~~~~~~~~~~~
ol Sidel effects?
l Brassyl taste,l burningl sensationl inl thel mouthl andl throat,l sorenessl ofl thel teeth
andl gums,l frontall headache,l coryza,l salvationl andl skinl eruptions
Answer:
Adultsl withl hyperthyroidism
l Patientsl whol havel notl respondedl adequatelyl tol anti-thyroidl drugsl orl subtotal
thyroidectomy
l Thyroidl cancer
~~~~~~~~~
, l Brassyl taste,l burningl sensationl inl thel mouthl andl throat,l sorenessl ofl thel teeth
andl gums,l frontall headache,l coryza,l salvationl andl skinl eruptions
QUESTION
Whatl arel stagesl ofl menstruall cycle?
Answer:
ol Follicularl phase
ol Luteall phase
ol Fulll cyclel aboutl 28l days
QUESTION
Whatl arel estrogenl effectsl onl primaryl andl secondaryl sexl characteristics?
Answer:
ol Influencel thel physiologicl processesl relatedl tol reproduction
ol Affectsl thel ductall growthl inl thel breasts,l thel thickeningl andl cornificationl ofl thel
vaginal
epithelium,l thel proliferationl ofl thel uterinel epithelium,l andl thel copiousl secretionl of
thickenedl mucusl forml thel endocervicall glands
QUESTION
Metabolicl effectsl ofl Estrogen?
Answer:
ol Positivel effectl onl bonel mass—blockl bonel resorption
ol Favorablel effectsl onl cholesteroll levels
l Decreasel LDL,l raisel HDL
ol Effectl onl bloodl coagulation
l Increasingl thel levelsl ofl thel coagulationl factors
ol Affectl glucosel homeostasis
l Increasel insulinl sensitivityl andl promotel glucosel uptake
QUESTION
