MA MPJE FINAL EXAM 2026/2027 QUESTIONS AND
ANSWERS RATED A+
✔✔Retail pharmacies shall inform the department of public health of any improper
dispensing of prescription drugs that results in serious injury or death, as soon as is
reasonably and practically possible, but not later than 48 hours after discovery of the
improper dispensing.
a. True
b. False - ✔✔(b) False, [M.G.L Chapter 112: Section 39(D)(b)].
Stores or pharmacies engaged in the drug business, as defined in section 37, shall
inform the department of public health of any improper dispensing of prescription drugs
that results in serious injury or death, as defined by the department in regulations, as
soon as is reasonably and practically possible, but not later than 7 working days after
discovery of the improper dispensing.
✔✔A pharmacist is adding 1000 mg of pure codeine powder to 100 cc of Tylenol with
codeine Elixir (120 mg/12 mg/5 cc). The resultant mixture should be classified as:
a. Schedule II
b. Schedule III
c. Schedule IV
d. Schedule V - ✔✔(b) The compounded mixture should be classified as a Schedule III
controlled drug. The amount of Codeine present in the final mixture is 1.24 gms (1000
mg plus 240 mg), [21CFR1308.13(e)(ii)].
It has been stated under CSA that if a mixture contains less than 1.8 gms of Codeine
per 100 cc, it should be classified as a Schedule III controlled substance.
List of Schedule III controlled drugs:
______________________________
Amobarbital and noncontrolled active ingredients
Amobarbital suppository dosage form
Anabolic steroids
Barbituric acid derivative
Benzphetamine (Didrex, Inapetyl)
Buprenorphine (Buprenex, Temgesic)
Butabarbital (Butisol, Butibel)
,Butalbital (Fiorinal, Butalbital with aspirin)
Codeine and isoquinoline alkaloid (Codeine with papaverine or noscapine)
Codeine combination product (Empirin, Fiorinal, Tylenol, ASA or APAP w/codeine)
Dronabinol in sesame oil in soft gelatin capsule (Marinol)
Lysergic acid
Lysergic acid amide
Methyltestosterone (Android, Oreton, Testred, Virilon)
Nalorphine (Nalline)
Nandrolone (Deca-Durabolin, Durabolin, Durabolin-50)
Norethandrolone(Nilevar, Solevar)
Opium combination product (Paregoric)
Pentobarbital and noncontrolled active ingredients
Pentobarbital suppository dosage form
Phendimetrazine (Bontril)
Secobarbital and noncontrolled active ingredients
Secobarbital suppository dosage form
Testosterone (Android-T, Androlan, Depotest, Delatestryl)
Thiopental (Pentothal)
✔✔Which of the following drugs is classified as a Schedule III drug?
a. Fioricet
b. Fiorinal
c. Codeine
d. Lorazepam - ✔✔(b) Fiorinal (Butalbital with Aspirin) is classified as a Schedule III
drug, [Section 811(g) (3) (A) of the Controlled Substances Act].
,Fioricet contains: 325 mg of acetaminophen (APAP), 50 mg of butalbital, and 40 mg of
caffeine.
Fiorinal contains: 325 mg of aspirin (ASA), 50 mg of butalbital, and 40 mg of caffeine.
The only difference between these two is the aspirin in Fiorinal vs acetaminophen in
Fioricet. Interesting to note that Fiorinal is a scheduled class III substance, while Fioricet
has a non-scheduled status. It seems really strange because both combinations contain
equal amount of the controlled substance butalbital.
The exemption requires that one of the active ingredients be a non-narcotic controlled
substance and one of the others be a non-scheduled compound. The potential for
abuse is decreased if a sufficient amount of a non-controlled substance (e.g., aspirin or
acetaminophenn) is added.
The ratio required for exemption is 70 mg of acetaminophen to 15 mg of butalbital. In
contrast, the ratio of aspirin to butalbital is 188 mg to 15 mg.
The acetaminophen to butalbital ratio is approximately 97 mg to 15 mg in Fioricet, thus
it is exempt from scheduling. In Fiorinal the aspirin to butalbital ratio is approximately 97
mg to 15 mg, which is less than the 188mg:15mg ratio, so it is classified as a Schedule
III substance.
✔✔A registered pharmacist who manages and operates a pharmacy or pharmacy
department shall, within ten working days of the commencement or termination of
employment, report in writing to the Board such commencement or termination of
employment.
a. True
b. False - ✔✔(a) True, [247 CMR 6.03(3),(4),(6)].
A registered pharmacist who manages and operates a pharmacy or pharmacy
department shall, within ten working days of the commencement or termination of
employment, report in writing to the Board such commencement or termination of
employment.
Upon commencement of the employment of a registered pharmacist, the pharmacist's
employer or the pharmacist Manager of Record shall verify with the Board that the
pharmacist's personal registration issued by the Board is current.
A surviving spouse, executor or administrator of a registered pharmacist who has died
or the spouse of one who has become incapacitated who has been authorized to
continue operation of a pharmacy or pharmacy department shall, within five days of any
change in employment of a registered pharmacist, whether by dismissal, resignation,
lay-off or additional hiring, notify the Board thereof in writing.
, ✔✔A registrant who oversees or is engaged in the administration of vaccines must
complete at least 5 contact hours of continuing education on the topic of immunizations
during the two-year renewal cycle.
a. True
b. False - ✔✔(b) False, [247 CMR 4.03(4)(e)].
A registrant who oversees or is engaged in the administration of vaccines must
complete at least 1 contact hour of continuing education on the topic of immunizations
during the two-year renewal cycle.
✔✔Phenergan with Codeine syrup is classified as:
a. Schedule I
b. Schedule II
c. Schedule III
d. Schedule V - ✔✔(d) Phenergan with Codeine syrup is classified as a Schedule V
controlled drug, [21CFR1308.15].
List of Schedule V controlled drugs:
Codeine preparations - Not more than 200 mg per 100 ml or 100 gm (Robitussin AC,
Phenergan with Codeine).
Difenoxin preparations - Not more than 0.5 mg Difenoxin + 25mcg Atropine sulfate
(Motofen).
Dihydrocodeine preparations - Not more than 100 mg per 100 ml or 100 gm.
Diphenoxylate preparations- Not more than 2.5 mg Diphenoxylate + 25mcg Atropine
sulfate (Lomotil, Logen).
Ethylmorphine preparations - Not more than 100 mg per 100 ml or 100 gm.
Opium preparations - Not more than 100 mg per 100 ml or 100 gm (Parepectolin,
Kapectolin PG, Kaolin Pectin P.G.).
Lyrica - Pregabalin
Vimpat - Lacosamide
Potiga - Ezogabine(d) Phenergan with Codeine syrup is classified as a Schedule V
controlled drug, [21CFR1308.15].
List of Schedule V controlled drugs:
ANSWERS RATED A+
✔✔Retail pharmacies shall inform the department of public health of any improper
dispensing of prescription drugs that results in serious injury or death, as soon as is
reasonably and practically possible, but not later than 48 hours after discovery of the
improper dispensing.
a. True
b. False - ✔✔(b) False, [M.G.L Chapter 112: Section 39(D)(b)].
Stores or pharmacies engaged in the drug business, as defined in section 37, shall
inform the department of public health of any improper dispensing of prescription drugs
that results in serious injury or death, as defined by the department in regulations, as
soon as is reasonably and practically possible, but not later than 7 working days after
discovery of the improper dispensing.
✔✔A pharmacist is adding 1000 mg of pure codeine powder to 100 cc of Tylenol with
codeine Elixir (120 mg/12 mg/5 cc). The resultant mixture should be classified as:
a. Schedule II
b. Schedule III
c. Schedule IV
d. Schedule V - ✔✔(b) The compounded mixture should be classified as a Schedule III
controlled drug. The amount of Codeine present in the final mixture is 1.24 gms (1000
mg plus 240 mg), [21CFR1308.13(e)(ii)].
It has been stated under CSA that if a mixture contains less than 1.8 gms of Codeine
per 100 cc, it should be classified as a Schedule III controlled substance.
List of Schedule III controlled drugs:
______________________________
Amobarbital and noncontrolled active ingredients
Amobarbital suppository dosage form
Anabolic steroids
Barbituric acid derivative
Benzphetamine (Didrex, Inapetyl)
Buprenorphine (Buprenex, Temgesic)
Butabarbital (Butisol, Butibel)
,Butalbital (Fiorinal, Butalbital with aspirin)
Codeine and isoquinoline alkaloid (Codeine with papaverine or noscapine)
Codeine combination product (Empirin, Fiorinal, Tylenol, ASA or APAP w/codeine)
Dronabinol in sesame oil in soft gelatin capsule (Marinol)
Lysergic acid
Lysergic acid amide
Methyltestosterone (Android, Oreton, Testred, Virilon)
Nalorphine (Nalline)
Nandrolone (Deca-Durabolin, Durabolin, Durabolin-50)
Norethandrolone(Nilevar, Solevar)
Opium combination product (Paregoric)
Pentobarbital and noncontrolled active ingredients
Pentobarbital suppository dosage form
Phendimetrazine (Bontril)
Secobarbital and noncontrolled active ingredients
Secobarbital suppository dosage form
Testosterone (Android-T, Androlan, Depotest, Delatestryl)
Thiopental (Pentothal)
✔✔Which of the following drugs is classified as a Schedule III drug?
a. Fioricet
b. Fiorinal
c. Codeine
d. Lorazepam - ✔✔(b) Fiorinal (Butalbital with Aspirin) is classified as a Schedule III
drug, [Section 811(g) (3) (A) of the Controlled Substances Act].
,Fioricet contains: 325 mg of acetaminophen (APAP), 50 mg of butalbital, and 40 mg of
caffeine.
Fiorinal contains: 325 mg of aspirin (ASA), 50 mg of butalbital, and 40 mg of caffeine.
The only difference between these two is the aspirin in Fiorinal vs acetaminophen in
Fioricet. Interesting to note that Fiorinal is a scheduled class III substance, while Fioricet
has a non-scheduled status. It seems really strange because both combinations contain
equal amount of the controlled substance butalbital.
The exemption requires that one of the active ingredients be a non-narcotic controlled
substance and one of the others be a non-scheduled compound. The potential for
abuse is decreased if a sufficient amount of a non-controlled substance (e.g., aspirin or
acetaminophenn) is added.
The ratio required for exemption is 70 mg of acetaminophen to 15 mg of butalbital. In
contrast, the ratio of aspirin to butalbital is 188 mg to 15 mg.
The acetaminophen to butalbital ratio is approximately 97 mg to 15 mg in Fioricet, thus
it is exempt from scheduling. In Fiorinal the aspirin to butalbital ratio is approximately 97
mg to 15 mg, which is less than the 188mg:15mg ratio, so it is classified as a Schedule
III substance.
✔✔A registered pharmacist who manages and operates a pharmacy or pharmacy
department shall, within ten working days of the commencement or termination of
employment, report in writing to the Board such commencement or termination of
employment.
a. True
b. False - ✔✔(a) True, [247 CMR 6.03(3),(4),(6)].
A registered pharmacist who manages and operates a pharmacy or pharmacy
department shall, within ten working days of the commencement or termination of
employment, report in writing to the Board such commencement or termination of
employment.
Upon commencement of the employment of a registered pharmacist, the pharmacist's
employer or the pharmacist Manager of Record shall verify with the Board that the
pharmacist's personal registration issued by the Board is current.
A surviving spouse, executor or administrator of a registered pharmacist who has died
or the spouse of one who has become incapacitated who has been authorized to
continue operation of a pharmacy or pharmacy department shall, within five days of any
change in employment of a registered pharmacist, whether by dismissal, resignation,
lay-off or additional hiring, notify the Board thereof in writing.
, ✔✔A registrant who oversees or is engaged in the administration of vaccines must
complete at least 5 contact hours of continuing education on the topic of immunizations
during the two-year renewal cycle.
a. True
b. False - ✔✔(b) False, [247 CMR 4.03(4)(e)].
A registrant who oversees or is engaged in the administration of vaccines must
complete at least 1 contact hour of continuing education on the topic of immunizations
during the two-year renewal cycle.
✔✔Phenergan with Codeine syrup is classified as:
a. Schedule I
b. Schedule II
c. Schedule III
d. Schedule V - ✔✔(d) Phenergan with Codeine syrup is classified as a Schedule V
controlled drug, [21CFR1308.15].
List of Schedule V controlled drugs:
Codeine preparations - Not more than 200 mg per 100 ml or 100 gm (Robitussin AC,
Phenergan with Codeine).
Difenoxin preparations - Not more than 0.5 mg Difenoxin + 25mcg Atropine sulfate
(Motofen).
Dihydrocodeine preparations - Not more than 100 mg per 100 ml or 100 gm.
Diphenoxylate preparations- Not more than 2.5 mg Diphenoxylate + 25mcg Atropine
sulfate (Lomotil, Logen).
Ethylmorphine preparations - Not more than 100 mg per 100 ml or 100 gm.
Opium preparations - Not more than 100 mg per 100 ml or 100 gm (Parepectolin,
Kapectolin PG, Kaolin Pectin P.G.).
Lyrica - Pregabalin
Vimpat - Lacosamide
Potiga - Ezogabine(d) Phenergan with Codeine syrup is classified as a Schedule V
controlled drug, [21CFR1308.15].
List of Schedule V controlled drugs:
