PHARMACOLOGY HESI V2 CERTIFICATION
EVALUATION 2026 FULL SOLUTION VIEW
AHEAD QUESTIONS
◉ A nurse educator is reviewing medication dosages and factors
that influence medication metabolism with a group of nurses.
Medication dosages may need to be decreased for which of the
following reasons? (Select all that apply.)
A. Increased renal excretion
B. Increased medication-metabolizing enzymes
C. Liver failure
D. Peripheral vascular disease
E. Concurrent use of medication metabolized by the same pathway
Answer: ANS: C, E
Liver failure decreases metabolism and thus increase the
concentration of medication. This may require decreasing the
dosage of medication. When two medications are metabolized in the
same way, they may compete for metabolism, thereby increasing the
concentration of one or both medications.
Increased renal excretion may decrease concentration of the
medication, requiring increased dosage. Increased medication-
,metabolizing enzymes can decrease the concentration of the
medication. The dose might need increased. Peripheral vascular
disease may impair distribution, and more of the medication may be
needed.
◉ A nurse s preparing to administer eye drops to a client. Which of
the following are appropriate nursing interventions related to this
procedure? (Select all that apply.)
A. Using medical aseptic technique
B. Asking the client to look up at the ceiling
C. Having the client lie in a side-lying position
D. Dropping medication into the center of the client's conjunctival
sac
E. Instructing the client to close the eye gently
Answer: ANS:B, D, E
The medication should be dropped into the center of the
conjunctival sac to promote better distribution of the medication.
The client should close the eye gently to allow improved distribution
of the medication.
Surgical aseptic technique is used to administer eye drops. The
client should be sitting or in a supine position to facilitate proper
administration of eye drops.
,◉ A nurse is completing discharge teaching to a client who has a
new prescription for a transdermal medication. Which of the
following statements by the client indicates understanding of the
teaching?
A. "I will clean the site with an alcohol swab prior to applying the
patch."
B. "I will rotate the application site weekly."
C. "I will apply the patch to an area of skin with no hair."
D. "I will place the new patch on the site of the old patch."
Answer: ANS: C
Transdermal medication should be applied to a hairless area of skin
to promote absorption of medication.
The skin should be washed with soap and water and dried
thoroughly before applying a transdermal patch. Application sites
should be rotated on a daily basis to prevent skin irritation.
◉ A nurse is reviewing a client's health record and notes a new
prescription by the provider to verify the trough level of the client's
medication. Which of the following actions should the nurse take?
A. Have a blood specimen obtained immediately prior to the next
dose of medication.
B. Verify that the client has been on the medication for 24 hr before
ordering a blood specimen.
, C. Ask the client to provide a urine specimen after the next dose of
medication.
D. Begin administering the medication, and obtain a blood specimen.
Answer: ANS: A
To verify trough levels of a medication, a blood specimen is obtained
immediately before the next dose of medication.
◉ A nurse is preparing a client's medication. Which of the following
are legal responsibilities of the nurse? (Select all that apply.)
A. Maintaining skill competency
B. Determining the dosage
C. Monitoring for adverse effects
D. Safeguarding medications
E. Identifying the client's diagnosis
Answer: ANS: A, C, D
Determining medication dosage and identifying a diagnosis is the
role/responsibility of the provider. The nurse should be informed
about a client's diagnosis.
◉ A nurse is reviewing a client's health record and notes a new
prescription by the provider for lisinopril (Zestril) 10 mg PO every
day. The nurse should recognize this as which of the following types
of prescription?
A. Single prescription
EVALUATION 2026 FULL SOLUTION VIEW
AHEAD QUESTIONS
◉ A nurse educator is reviewing medication dosages and factors
that influence medication metabolism with a group of nurses.
Medication dosages may need to be decreased for which of the
following reasons? (Select all that apply.)
A. Increased renal excretion
B. Increased medication-metabolizing enzymes
C. Liver failure
D. Peripheral vascular disease
E. Concurrent use of medication metabolized by the same pathway
Answer: ANS: C, E
Liver failure decreases metabolism and thus increase the
concentration of medication. This may require decreasing the
dosage of medication. When two medications are metabolized in the
same way, they may compete for metabolism, thereby increasing the
concentration of one or both medications.
Increased renal excretion may decrease concentration of the
medication, requiring increased dosage. Increased medication-
,metabolizing enzymes can decrease the concentration of the
medication. The dose might need increased. Peripheral vascular
disease may impair distribution, and more of the medication may be
needed.
◉ A nurse s preparing to administer eye drops to a client. Which of
the following are appropriate nursing interventions related to this
procedure? (Select all that apply.)
A. Using medical aseptic technique
B. Asking the client to look up at the ceiling
C. Having the client lie in a side-lying position
D. Dropping medication into the center of the client's conjunctival
sac
E. Instructing the client to close the eye gently
Answer: ANS:B, D, E
The medication should be dropped into the center of the
conjunctival sac to promote better distribution of the medication.
The client should close the eye gently to allow improved distribution
of the medication.
Surgical aseptic technique is used to administer eye drops. The
client should be sitting or in a supine position to facilitate proper
administration of eye drops.
,◉ A nurse is completing discharge teaching to a client who has a
new prescription for a transdermal medication. Which of the
following statements by the client indicates understanding of the
teaching?
A. "I will clean the site with an alcohol swab prior to applying the
patch."
B. "I will rotate the application site weekly."
C. "I will apply the patch to an area of skin with no hair."
D. "I will place the new patch on the site of the old patch."
Answer: ANS: C
Transdermal medication should be applied to a hairless area of skin
to promote absorption of medication.
The skin should be washed with soap and water and dried
thoroughly before applying a transdermal patch. Application sites
should be rotated on a daily basis to prevent skin irritation.
◉ A nurse is reviewing a client's health record and notes a new
prescription by the provider to verify the trough level of the client's
medication. Which of the following actions should the nurse take?
A. Have a blood specimen obtained immediately prior to the next
dose of medication.
B. Verify that the client has been on the medication for 24 hr before
ordering a blood specimen.
, C. Ask the client to provide a urine specimen after the next dose of
medication.
D. Begin administering the medication, and obtain a blood specimen.
Answer: ANS: A
To verify trough levels of a medication, a blood specimen is obtained
immediately before the next dose of medication.
◉ A nurse is preparing a client's medication. Which of the following
are legal responsibilities of the nurse? (Select all that apply.)
A. Maintaining skill competency
B. Determining the dosage
C. Monitoring for adverse effects
D. Safeguarding medications
E. Identifying the client's diagnosis
Answer: ANS: A, C, D
Determining medication dosage and identifying a diagnosis is the
role/responsibility of the provider. The nurse should be informed
about a client's diagnosis.
◉ A nurse is reviewing a client's health record and notes a new
prescription by the provider for lisinopril (Zestril) 10 mg PO every
day. The nurse should recognize this as which of the following types
of prescription?
A. Single prescription
