NAPLEX PREVIEWED TEST
QUESTIONS AND CORRECT
ANSWERS GRADED A+ 2025-
2026
What is the equation for corrected phenytoin? - ANS-CP= measured serum phenytoin/(0.2*albumin)+0.1
What is the principle intracellular cation? - ANS-potassium
Principle extracellular is Sodium
How many mL in a teaspoon? - ANS-5 mL
how many mL in a tablespoon - ANS-15 mL
how many mL in a cup? - ANS-240 mL
how many mL in an ounce? - ANS-29.6 mL
how many mL in a pint? - ANS-473 mL
how many mL in a gallon? - ANS-3785 mL
How do we calculate mols or mmols of a substance? - ANS-mol= g/MW
,mmol= mg/MW
How many mg are in one grain? - ANS-65 mg/grain
How many lbs in a kg? - ANS-2.2lbs/kg
What is the conversion of aminophylline to theophylline? - ANS-we multiply the aminophylline by 0.8 to
get the equivalent theophylline
What is the conversion of theophylline to aminophylline? - ANS-divide the amount of theophylline by
0.8 to get the equivalent aminophylline
How do we get the ratio strength from the percent strength? - ANS-ratio strength= 100/% strength
How do we get the percent strength from the ratio strength? - ANS-% strength= 100/ratio strength
How do we convert PPM to percent strength? - ANS--PPM to % strength, move decimal left 4 places
-% strength to PPM, move decimal place right 4 places
specific gravity - ANS-SG= grams of substance/mL
mEq - ANS-mEq= mg x valence/MW
Which chemicals have 2 valences? - ANS-Calcium carbonate
Calcium chloride
Ferrous sulfate
Magnesium sulfate
mOsmol/L - ANS-mOsmol/L= [wt of substance (g/L)/MW (g/mole)] x number of particles x 1000
,Equation for anion gap` - ANS-Na - (Cl + Bicarbonate)
How much elemental calcium is found in calcium carbonate and calcium citrate? - ANS-40% in carbonate
20% in citrate
How much elemental Iron is in ferrous fumarate, ferrous sulfate, and ferrous gluconate? - ANS-
fumarate: 108 mg
sulfate: 65 mg of 325mg (20%)
gluconate 35 mg
How is absolute neutrophil count calculated? - ANS-ANC= WBC x [(%segs + %bands)/100]
What is the formula to determine a patient's total energy expenditure? - ANS-TEE= BEE x activity factor
X stress factor
What is the equation to find pH of a weak acid? - ANS-pH = pKa + log(salt/acid)
What is the equation to find pH of a weak base? - ANS-pH = (pKw - pKb) + log(base/salt)
what can we tell about ionization of acids from the pH and the pKa? - ANS-pH > pKa more acid is ionized
pH = pKa ionized and unionized are equal
pH < pKa more acid is unionized
An ionized drug is more soluble but cannot easily cross lipid membranes and vice versa
How are the ABG measurements written out on the exam? - ANS-pH/pCO2/pO2/HCO3/O2
What are the normal values for pH, HCO3, and pCO2? - ANS-pH = 7.35-7.45
, HCO3 = 38-42
pCO2 = 22-28
When adding calcium and phosphate to TPN what should be considered? - ANS--Use calcium gluconate
over calcium chloride because it is less reactive and a lower rate of precipitation.
-Add phosphate first then add calcium at the end of the prep
-when added together don't exceed 45 mEq/L
BMI - ANS-weight in kg/height in meter^2
BSA - ANS-BSA = SQR [weight(kg) x height (cm)/3600]
How many kcals are in 10%, 20%, and 30% intravenous fat emulsions? How much fat is needed for TPN?
- ANS-10% = 1.1 kcal/mL
20% = 2 kcal/mL
30% = 3 kcal/mL
Fat for TPN = 9 kcal/gram
How many kcals do amino acids and dextrose provide in TPN? - ANS-Amino acids 4 kcal/gram
dextrose 3.4 kcal/gram
what is the pKa? - ANS-The pKa is the pH at which half the drug is 50% ionized. This is half the
neutralization or equivalence point. The neutralization or equivalence point is at a much higher pH and
occurs when the acid has been neutralized.
what is the correct calcium equation? - ANS-Corrected Ca = [(4.0-albumin) x 0.8] + serum calcium
What is the equation for absolute bioavailability? - ANS-F= 100 x (AUC extravascular/AUC intravascular)
x (Dose intravascular/Dose extravascular)
QUESTIONS AND CORRECT
ANSWERS GRADED A+ 2025-
2026
What is the equation for corrected phenytoin? - ANS-CP= measured serum phenytoin/(0.2*albumin)+0.1
What is the principle intracellular cation? - ANS-potassium
Principle extracellular is Sodium
How many mL in a teaspoon? - ANS-5 mL
how many mL in a tablespoon - ANS-15 mL
how many mL in a cup? - ANS-240 mL
how many mL in an ounce? - ANS-29.6 mL
how many mL in a pint? - ANS-473 mL
how many mL in a gallon? - ANS-3785 mL
How do we calculate mols or mmols of a substance? - ANS-mol= g/MW
,mmol= mg/MW
How many mg are in one grain? - ANS-65 mg/grain
How many lbs in a kg? - ANS-2.2lbs/kg
What is the conversion of aminophylline to theophylline? - ANS-we multiply the aminophylline by 0.8 to
get the equivalent theophylline
What is the conversion of theophylline to aminophylline? - ANS-divide the amount of theophylline by
0.8 to get the equivalent aminophylline
How do we get the ratio strength from the percent strength? - ANS-ratio strength= 100/% strength
How do we get the percent strength from the ratio strength? - ANS-% strength= 100/ratio strength
How do we convert PPM to percent strength? - ANS--PPM to % strength, move decimal left 4 places
-% strength to PPM, move decimal place right 4 places
specific gravity - ANS-SG= grams of substance/mL
mEq - ANS-mEq= mg x valence/MW
Which chemicals have 2 valences? - ANS-Calcium carbonate
Calcium chloride
Ferrous sulfate
Magnesium sulfate
mOsmol/L - ANS-mOsmol/L= [wt of substance (g/L)/MW (g/mole)] x number of particles x 1000
,Equation for anion gap` - ANS-Na - (Cl + Bicarbonate)
How much elemental calcium is found in calcium carbonate and calcium citrate? - ANS-40% in carbonate
20% in citrate
How much elemental Iron is in ferrous fumarate, ferrous sulfate, and ferrous gluconate? - ANS-
fumarate: 108 mg
sulfate: 65 mg of 325mg (20%)
gluconate 35 mg
How is absolute neutrophil count calculated? - ANS-ANC= WBC x [(%segs + %bands)/100]
What is the formula to determine a patient's total energy expenditure? - ANS-TEE= BEE x activity factor
X stress factor
What is the equation to find pH of a weak acid? - ANS-pH = pKa + log(salt/acid)
What is the equation to find pH of a weak base? - ANS-pH = (pKw - pKb) + log(base/salt)
what can we tell about ionization of acids from the pH and the pKa? - ANS-pH > pKa more acid is ionized
pH = pKa ionized and unionized are equal
pH < pKa more acid is unionized
An ionized drug is more soluble but cannot easily cross lipid membranes and vice versa
How are the ABG measurements written out on the exam? - ANS-pH/pCO2/pO2/HCO3/O2
What are the normal values for pH, HCO3, and pCO2? - ANS-pH = 7.35-7.45
, HCO3 = 38-42
pCO2 = 22-28
When adding calcium and phosphate to TPN what should be considered? - ANS--Use calcium gluconate
over calcium chloride because it is less reactive and a lower rate of precipitation.
-Add phosphate first then add calcium at the end of the prep
-when added together don't exceed 45 mEq/L
BMI - ANS-weight in kg/height in meter^2
BSA - ANS-BSA = SQR [weight(kg) x height (cm)/3600]
How many kcals are in 10%, 20%, and 30% intravenous fat emulsions? How much fat is needed for TPN?
- ANS-10% = 1.1 kcal/mL
20% = 2 kcal/mL
30% = 3 kcal/mL
Fat for TPN = 9 kcal/gram
How many kcals do amino acids and dextrose provide in TPN? - ANS-Amino acids 4 kcal/gram
dextrose 3.4 kcal/gram
what is the pKa? - ANS-The pKa is the pH at which half the drug is 50% ionized. This is half the
neutralization or equivalence point. The neutralization or equivalence point is at a much higher pH and
occurs when the acid has been neutralized.
what is the correct calcium equation? - ANS-Corrected Ca = [(4.0-albumin) x 0.8] + serum calcium
What is the equation for absolute bioavailability? - ANS-F= 100 x (AUC extravascular/AUC intravascular)
x (Dose intravascular/Dose extravascular)
