NR565 / NR 565 ADVANCED PHARMACOLOGY CARE MIDTERM EXAM | PRACTICE QUESTIONS
& ANSWERS | STUDY GUIDE 2026/2027
Used in children aged 9-11 and 19-21, and adults every 5 years after 20, with greater risk for
those with diabetes and a risk score >7.5% - correct answer ✔✔ASCVD Risk Score
Can be used in pregnancy/breastfeeding, as monotherapy or adjunct therapy with a statin or
fibrate - correct answer ✔✔Ezetimibe Use
Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreasing absorption from
the small intestine, without affecting triglycerides - correct answer ✔✔Ezetimibe
Non-drug measures to lower LDL, including diet, exercise, weight control, and smoking cessation
- correct answer ✔✔Lifestyle Changes for High Cholesterol
Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for generally well-tolerated
side effects - correct answer ✔✔Minimizing Side Effects
Direct relaxant effect on vascular smooth muscles, dilation of coronary vessels, reduction of
preload and afterload, and promotion of vasodilation - correct answer ✔✔Organic Nitrates
Therapeutic Action
Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes, including grapefruit
juice, HIV protease inhibitors, macrolide antibiotics, azole antifungal drugs, and some CCB -
correct answer ✔✔Ranolazine Contraindications
Avoid in children under 10 - correct answer ✔✔Statin Prescription Age
Promotes relaxation of coronary artery spasm, increasing cardiac oxygen supply - correct
answer ✔✔CCB Role in Variant Angina
, Aldosterone antagonist that promotes myocardial remodeling and fibrosis to help with
symptoms - correct answer ✔✔HF Worsening Symptoms Medication
Promotes relaxation of peripheral arterioles, decreasing afterload and reducing cardiac oxygen
demand - correct answer ✔✔CCB Stable Angina
Prescribe a BB to help with increased heart rate - correct answer ✔✔Nitro Patches Side Effect
Response
When not used correctly, they lead to increased side effects, adverse reactions, and toxicity -
correct answer ✔✔CYP450 Inhibitors and Reducers
In patients with infrequent flareups (less than three per year), NSAIDs are the first line agent for
relieving pain - correct answer ✔✔Gouty Arthritis Treatment Decision
Prescribe a glucocorticoid (prednisone) or make dietary changes - correct answer ✔✔Gouty
Arthritis NSAID Ineffectiveness
Considered for long term treatment if a person has three or more gouty attacks per year -
correct answer ✔✔Colchicine Long Term Treatment
Should not be taken with statins or CYP3A4 inhibitors - correct answer ✔✔Colchicine
Contraindications
Nausea, vomiting, diarrhea, myelosuppression, myopathy, and rhabdomyolysis - correct answer
✔✔Colchicine Adverse Effects
& ANSWERS | STUDY GUIDE 2026/2027
Used in children aged 9-11 and 19-21, and adults every 5 years after 20, with greater risk for
those with diabetes and a risk score >7.5% - correct answer ✔✔ASCVD Risk Score
Can be used in pregnancy/breastfeeding, as monotherapy or adjunct therapy with a statin or
fibrate - correct answer ✔✔Ezetimibe Use
Cholesterol Absorption Inhibitor that lowers cholesterol levels by decreasing absorption from
the small intestine, without affecting triglycerides - correct answer ✔✔Ezetimibe
Non-drug measures to lower LDL, including diet, exercise, weight control, and smoking cessation
- correct answer ✔✔Lifestyle Changes for High Cholesterol
Non-statins like fibrates, ezetimibe, bile acid sequestrants, or statins for generally well-tolerated
side effects - correct answer ✔✔Minimizing Side Effects
Direct relaxant effect on vascular smooth muscles, dilation of coronary vessels, reduction of
preload and afterload, and promotion of vasodilation - correct answer ✔✔Organic Nitrates
Therapeutic Action
Inhibited by CYP3A4 inhibitors, increasing the risk of torsades de pointes, including grapefruit
juice, HIV protease inhibitors, macrolide antibiotics, azole antifungal drugs, and some CCB -
correct answer ✔✔Ranolazine Contraindications
Avoid in children under 10 - correct answer ✔✔Statin Prescription Age
Promotes relaxation of coronary artery spasm, increasing cardiac oxygen supply - correct
answer ✔✔CCB Role in Variant Angina
, Aldosterone antagonist that promotes myocardial remodeling and fibrosis to help with
symptoms - correct answer ✔✔HF Worsening Symptoms Medication
Promotes relaxation of peripheral arterioles, decreasing afterload and reducing cardiac oxygen
demand - correct answer ✔✔CCB Stable Angina
Prescribe a BB to help with increased heart rate - correct answer ✔✔Nitro Patches Side Effect
Response
When not used correctly, they lead to increased side effects, adverse reactions, and toxicity -
correct answer ✔✔CYP450 Inhibitors and Reducers
In patients with infrequent flareups (less than three per year), NSAIDs are the first line agent for
relieving pain - correct answer ✔✔Gouty Arthritis Treatment Decision
Prescribe a glucocorticoid (prednisone) or make dietary changes - correct answer ✔✔Gouty
Arthritis NSAID Ineffectiveness
Considered for long term treatment if a person has three or more gouty attacks per year -
correct answer ✔✔Colchicine Long Term Treatment
Should not be taken with statins or CYP3A4 inhibitors - correct answer ✔✔Colchicine
Contraindications
Nausea, vomiting, diarrhea, myelosuppression, myopathy, and rhabdomyolysis - correct answer
✔✔Colchicine Adverse Effects
