NURS 3366 Pathophysiologic Processes – Exam 2
University of Texas at Arlington (UTA) – 150 Practice
Questions with Answers
About the NURS 3366 Exam 2
Course: NURS 3366 – Pathophysiologic Processes: Implications for Nursing
Institution: University of Texas at Arlington (UTA)
Exam Format: multiple-choice questions
Weight: Exam 2 is worth 14 points
Exam 2 Content Areas (Fall 2024 Blueprint):
Approx.
Content Area
Questions
1st Line of Defense (skin, mucous membranes, Sjogren's syndrome) 8-10
2nd Line of Defense (inflammation, mast cells, mediators, phagocytes) 8-10
3rd Line of Defense (adaptive immunity, active/passive, cell-
8-10
mediated/humoral)
Disorders of Hyper-inflammation (septic shock) and Hypo-inflammation 4-5
, Approx.
Content Area
Questions
Hypersensitivity Reactions & Autoimmune Disorders 4-5
Section 1: Lines of Defense & Innate Immunity (Questions 1-30)
1. What are the three basic aspects of the 2nd line of defense in the immune system?
A) Skin, mucous membranes, and tears
B) Normal inflammatory processes, role of mast cells, plasma proteins, acute phase
biochemical mediators, and phagocytes
C) Antibodies, T-cells, and memory cells
D) Vaccines, immunoglobulins, and artificial immunity
Answer: B
Rationale: The 2nd line of defense includes normal inflammatory processes, the role of
mast cells, plasma proteins, acute phase biochemical mediators, and phagocytes such as
neutrophils and macrophages.
2. Innate (natural) resistance refers to:
A) Defense mechanisms we are born with
B) Immunity acquired after vaccination
C) Immunity acquired after infection
D) Antibody-mediated immunity
Answer: A
,Rationale: Innate (natural) resistance refers to defense mechanisms we are born with,
providing immediate, non-specific protection.
3. The 1st line of defense includes which of the following?
A) Inflammation and phagocytosis
B) Skin and mucous membranes
C) Antibodies and T-cells
D) Fever and complement activation
Answer: B
Rationale: The 1st line of defense consists of the body's physical barriers—skin and
mucous membranes—which provide immediate, non-specific protection.
4. Which of the following is a stressor that can breach the skin's defense?
A) Lacerations, abrasions, and punctures
B) Fever and inflammation
C) Antibody deficiency
D) Complement activation
Answer: A
Rationale: Stressors that can breach the skin's defense include lacerations, abrasions, and
punctures.
5. Sjogren's syndrome is an autoimmune disease that primarily affects:
A) The skin and mucous membranes
B) The respiratory system only
C) Lubricating fluids throughout the body (dry eye syndrome)
D) The cardiovascular system
, Answer: C
Rationale: Sjogren's syndrome is an autoimmune disease that dries up all lubricating fluids
in the body, leading to dry eye syndrome and other manifestations.
6. The eye's defense mechanisms include:
A) Cilia and mucus
B) Tears and eyelashes
C) Stomach acid and saliva
D) Urine flow and vaginal secretions
Answer: B
Rationale: The eye's defense includes tears and eyelashes, which trap and remove
pathogens.
7. Stressors that can breach the eye's defense include:
A) Lacerations and punctures
B) Dry eye syndrome and Sjogren's syndrome
C) Fever and inflammation
D) Antibody deficiency
Answer: B
Rationale: Stressors that can breach the eye's defense include dry eye syndrome and
Sjogren's syndrome, which reduce protective tear production.
8. The respiratory system's defenses include all of the following EXCEPT:
A) Mucus and hair in the nose
B) Cilia of cells in the bronchi
University of Texas at Arlington (UTA) – 150 Practice
Questions with Answers
About the NURS 3366 Exam 2
Course: NURS 3366 – Pathophysiologic Processes: Implications for Nursing
Institution: University of Texas at Arlington (UTA)
Exam Format: multiple-choice questions
Weight: Exam 2 is worth 14 points
Exam 2 Content Areas (Fall 2024 Blueprint):
Approx.
Content Area
Questions
1st Line of Defense (skin, mucous membranes, Sjogren's syndrome) 8-10
2nd Line of Defense (inflammation, mast cells, mediators, phagocytes) 8-10
3rd Line of Defense (adaptive immunity, active/passive, cell-
8-10
mediated/humoral)
Disorders of Hyper-inflammation (septic shock) and Hypo-inflammation 4-5
, Approx.
Content Area
Questions
Hypersensitivity Reactions & Autoimmune Disorders 4-5
Section 1: Lines of Defense & Innate Immunity (Questions 1-30)
1. What are the three basic aspects of the 2nd line of defense in the immune system?
A) Skin, mucous membranes, and tears
B) Normal inflammatory processes, role of mast cells, plasma proteins, acute phase
biochemical mediators, and phagocytes
C) Antibodies, T-cells, and memory cells
D) Vaccines, immunoglobulins, and artificial immunity
Answer: B
Rationale: The 2nd line of defense includes normal inflammatory processes, the role of
mast cells, plasma proteins, acute phase biochemical mediators, and phagocytes such as
neutrophils and macrophages.
2. Innate (natural) resistance refers to:
A) Defense mechanisms we are born with
B) Immunity acquired after vaccination
C) Immunity acquired after infection
D) Antibody-mediated immunity
Answer: A
,Rationale: Innate (natural) resistance refers to defense mechanisms we are born with,
providing immediate, non-specific protection.
3. The 1st line of defense includes which of the following?
A) Inflammation and phagocytosis
B) Skin and mucous membranes
C) Antibodies and T-cells
D) Fever and complement activation
Answer: B
Rationale: The 1st line of defense consists of the body's physical barriers—skin and
mucous membranes—which provide immediate, non-specific protection.
4. Which of the following is a stressor that can breach the skin's defense?
A) Lacerations, abrasions, and punctures
B) Fever and inflammation
C) Antibody deficiency
D) Complement activation
Answer: A
Rationale: Stressors that can breach the skin's defense include lacerations, abrasions, and
punctures.
5. Sjogren's syndrome is an autoimmune disease that primarily affects:
A) The skin and mucous membranes
B) The respiratory system only
C) Lubricating fluids throughout the body (dry eye syndrome)
D) The cardiovascular system
, Answer: C
Rationale: Sjogren's syndrome is an autoimmune disease that dries up all lubricating fluids
in the body, leading to dry eye syndrome and other manifestations.
6. The eye's defense mechanisms include:
A) Cilia and mucus
B) Tears and eyelashes
C) Stomach acid and saliva
D) Urine flow and vaginal secretions
Answer: B
Rationale: The eye's defense includes tears and eyelashes, which trap and remove
pathogens.
7. Stressors that can breach the eye's defense include:
A) Lacerations and punctures
B) Dry eye syndrome and Sjogren's syndrome
C) Fever and inflammation
D) Antibody deficiency
Answer: B
Rationale: Stressors that can breach the eye's defense include dry eye syndrome and
Sjogren's syndrome, which reduce protective tear production.
8. The respiratory system's defenses include all of the following EXCEPT:
A) Mucus and hair in the nose
B) Cilia of cells in the bronchi
