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USMLE Step 3 Dermatology & Ophthalmology Questions & Answers | Complete Practice Test | Latest 2026–2027 with Verified Answers

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Prepare for USMLE Step 3 Dermatology & Ophthalmology with this comprehensive practice test featuring verified questions and answers. This high-yield exam resource covers common dermatologic disorders, skin infections, inflammatory skin diseases, dermatologic emergencies, ophthalmic anatomy, red eye disorders, glaucoma, cataracts, retinal diseases, ocular trauma, visual disturbances, diagnosis, clinical management, and evidence-based treatment strategies commonly tested on the USMLE Step 3. Ideal for medical students and physicians preparing for board exams, self-assessment, and comprehensive review during the 2026–2027 exam cycle.

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USMLE Step 3 - Dermatology &
Ophthalmology Exam



All Questions and Correct Answers |
Graded A+ | Verified Answers | Latest
Version (Just Released)

, Seborrheic dermatitis erythematous, pruritic plaques with greasy scale on scalp, central face, ears

cause by pityrosporum oval

Tx:
low potency topical steroids
topical antifungal
Zinc pyrithione shampoo


Keloids B9 fibrous growths, scar tissue secondary over production of extracellular matrix
and dermal fibroblast

Tx:
intralesional glucocorticoids

can recur


Candidial diaper infection presence of tomato-red plaques, satellite papule found on folds

Tx:
antimycotic agents (clotrimazole, nystatin)


Diaper Dermatitis differs from candida in that it doesn't involved the folds

Tx:
zinc oxide crease


Lichen Planus 4Ps: pruritic, planar, polygonal, purple

associated with advance liver disease due to HCV

Dx:
skin biopsy


Porphyria cutanea tarda characterized by painless blisters, hyperthyroidism, hyper pigmentation,
associated with hep C

triggered by injection of certain substances (ethanol, estrogens)


Tinea capitis superficial dermatophytosis, MC in children, causes scaly patches with slight
erythema and hair loss

Dx:
KOH prep

Tx:
Oral griseofulvin, terbinafine


Pediculosis (lice & crabs) tends to include the head, easily transmitted by sharing hats and hairbrushes

Dx:
organism can readily be seen attached to hair-bearing areas

tx:
Topical permethrin


Scabies involves primarily the web spaces of the hands an feed, extreme itching

Dx:
scraping out of the organism after mineral oil is applied to a burrow

tx:
Topical 5% permethrin


Rubella (German measles) High fever and red maculopapular rash together, starts head and spread down
body

occipital adenopathy

Tx: supportive care

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