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AINS REVIEW 2026 UPDATED QUESTIONS VERIFIED ANSWERS COMPLETE GUIDE

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AINS REVIEW 2026 UPDATED QUESTIONS VERIFIED ANSWERS COMPLETE GUIDE

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AINS REVIEW 2026 UPDATED QUESTIONS
VERIFIED ANSWERS COMPLETE GUIDE

◉ Care sunt factorii de risc asociati nefrotoxicitatii?
Answer: Insuficienta cardiaca
Ciroza hepatica
Tratamentul cu diuretice, IEC
Restrictie de sodiu


◉ Ce reactii cardiovasculare au AINS-urile?
Answer: -Efect protrombotic al COX 2 selectivi -Atat AINS neselective
cat si coxibii cresc riscul de evenimente CV


Dar
Spre deosebire de reactiile adverse digestive care apar precoce,
riscul reactiilor adverse CV precum infarctul miocardic, accidentul
vascular cerebral sau decesul de cauza CV este deosebit de mic la
pacientii tratati pe termen scurt cu AINS (ex. tendinite, entorse)


◉ Ce risc trombotic are diclofenacul?
Answer: Similar cu al coxibilor

, ◉ Care AINS prezinta cel mai mic risc al evenimentelor CV severe?
Answer: Naproxen


◉ Ibuprofenul ce risc CV are?
Answer: - In doza mica nu prezinta risc crescut CV (1200 mg).
-Insa, doza crescuta (2400 mg/zi) este asociata cu cresterea riscului
de evenimente CV, similar diclofenacului si inhibitorilor de COX2


◉ Ce reactie adversa respiratorie pot produce AINS-urile?
Answer: Bronhospasm (astm) produs de AINS-uri


◉ Ce inseamna bronhospasm indus de AINS-uri? Unde este descris
initial?
Answer: -Descris initial la acidul acetilsalicilic
• Pacientii care au dezvoltat sensibilitate la un AINS sunt predispusi
sa reactioneze identic la
altul
• COX2 selectivi - risc mai scazut de
bronhospasm în comparatie cu AINS
neselective
• Nu este o reactie alergica, ci una idiosincrazica!

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