FLORIDA MPJE FINAL EXAM 2026/2027 QUESTIONS AND
SOLUTIONS RATED A+
✔✔Controlled Substance - CII - ✔✔- no refills
- no post dating of Rx
- No Transfers
- 90 day limit max
- oral Rx only in emergency - limits amount - pharmacist writes the Rx (authorization for
emergency dispensing) attaches original when it arrives. Must obtain within 7 days.
- fax Rx only ok if - Home infusion IV for pain, Residents of LTCF, or state licensed
Hospice facility
- Partial fill ok - complete filling in 72 hours - if can't then notify MD and void remainder.
- LTCF partial refills - valid for 60 days from date written. Each fill the RPh must
document date of fill, qty dispensed and qty remaining and sign.
- RPh may not change essential element on Rx: (Drug, Patient, Signature). May change
address, qty, strength, directions (with auth).
- Order on 222 Forms - may also use to transfer to another pharmacy. May use to send
to reverse distributors.
✔✔What pieces of information may a RPh change on a CII Rx? - ✔✔Address, Quantity,
Strength, Directions with authorization from MD
✔✔Controlled Substance - CIII-IV - ✔✔- five refills in six months
- 1 transfer permitted unless share a common database then may transfer as many time
as needed as long as there are refills
- partial fills permitted - don't exceed total quantity or six month duration
- In Florida pharmacists AND interns may transfer controlled substance prescriptions
- may be written, oral or faxed (need original)
- may make any changes with consultation of MD
- no special order form - orders kept readily retrievable
✔✔Controlled Substance - CV - ✔✔- most are available without a prescription and
indicated as cough or antidiarrheal
- Lyrica (pregabalin) requires Rx
✔✔Controlled Substance - CV - Limits - ✔✔120mg Codeine
60mg Dihydrocodeine
30mg ethyl morphine
240mg opium
within a 48 hour period
✔✔SLCPS - ✔✔Schedule Listed Chemical Product
✔✔SLCPS Examples - ✔✔- Ephedrine, pseudoephedrine, phenylpropanolamine
must train staff and keep training records
,sales limits enforced
stored behind counter or in locked cabinet
written or electronic log book maintained
✔✔SLCPS - List 1 Chemicals - ✔✔Drugs involved in the manufacture of a CS
✔✔SLCPS - List 2 Chemicals - ✔✔Solvents involved in the manufacture of a CS
✔✔Is electronic prescribing of Controlled Substances allowed? - ✔✔Yes
✔✔Name the Prescription Filing System Options - ✔✔1. Three separate files: CII, CIII-
V, and non controls
2. Two separate files: CII, CIII-V and non controls - must stamp a red C >1 inch in lower
right corner
3 Two separate files: CII- V, non controls - must stamp CIII-V with a red C in lower right
corner
✔✔How are Controlled Substances Stored? - ✔✔One of three ways:
1. Locked cabinet
2. Dispersed throughout the pharmacy
3. Combination of both
There is no special requirement for CII to be locked up - may be dispersed.
✔✔Do hospitals need to follow label requirements? - ✔✔No
✔✔Can you mail controlled substances? - ✔✔Yes - in US only. Package must be
unmarked regarding contents
✔✔When do you fill out a DEA Form 106 - ✔✔Where there is theft or significant loss of
a controlled substance.
✔✔May Midlevel practitioners prescribe Controlled Substances in Florida? - ✔✔No.
An agent can phone in a prescription at the request of the registrant (ie a receptionist
may call it in) including emergency CII prescriptions.
✔✔Can a Military MD write an Rx for a controlled substance without a DEA number? -
✔✔Yes. Must use Military number. May fill at a community pharmacy.
✔✔Can Hospital Interns and Residents write an Rx for a controlled substance without a
DEA number? - ✔✔Yes. May use the hospital DEA number plus their hospital ID
number at the end. May fill Rx at community pharmacy and would just use the hospital
DEA.
,✔✔Is Central Fill of Controlled Substances permitted? - ✔✔Yes for CIII-V. Local
pharmacy must write date, pharmacist transmitting and Central Fill on the face of
prescription along with Central fill pharmacy name, address, DEA #.
Store records for two years from date of last fill.
✔✔Can you Central Fill CII prescriptions? - ✔✔NO
✔✔What happens when you execute a 222 Form? - ✔✔- Pharmacy places order and
keeps Copy 3
- Copy 1&2 go to the supplier. Supplier fills the order and keeps Copy 1. Completes
copy 1&2 and mails copy 2 to the DEA.
- Pharmacy completes copy 3 upon receipt of order with containers and date received.
** Supplier can endorse form to another if unable to complete the order.
✔✔Controlled Substances Refills? - ✔✔CII - NO
C III-V Yes - 5 in 6 months
✔✔Controlled Substances Transfer between pharmacies? - ✔✔CII - NO
CIII-V - 1 allowed (unless share same database)
✔✔Controlled Substances Transfer of bulk drugs / pharmacies? - ✔✔CII - Requires 222
CIII-V - requires complete invoice
✔✔Controlled Substances - Oral Rx Allowed? - ✔✔CII - In emergency
CIII - V - Yes
✔✔Controlled Substances - Fax Rx Allowed? - ✔✔CII - Yes to prepare but will need
hard copy to dispense
CIII - V - Yes to prepare but will need hard copy to dispense
✔✔Controlled Substances - Electronic Rx Allowed? - ✔✔CII - Yes subject to security
requirments
CIII - V Yes
✔✔Controlled Substances - Partial Fills Allowed? - ✔✔CII - Generally No but may fill
partial if can't supply entire amount. Must complete within 72 hours. Yes for terminally ill
and LTCF but must mark "terminally ill" or "LTCF patient" on prescription
CIII-V - Yes, just not more than qty or 6 month duration.
✔✔Controlled Substances - Inventory Requirements - ✔✔CII - Exact count
CIII - V - estimated count unless bottle holds more than 1000 units then will need an
exact count.
** Initial inventory required then every two years thereafter.
, Inventory must have drug name, strength, dosage form, number of units in each
container, number of containers (written, typed, or printed - kept on site and includes
inventory date and time and opening or close of business).
✔✔DEA Form 41 - ✔✔Documents disposal and destruction of scheduled drugs
✔✔DEA Form 106 - ✔✔Unusual or excessive loss, disappearance or theft
✔✔DEA Form 222 - ✔✔Order CI and CII (can be electronic - CSOS)
✔✔DEA Form 224 - ✔✔New application for Retail pharmacy, hospital, practitioner,
teaching institution, mid level practioner
✔✔DEA Form 224a - ✔✔Renewal application - every 3 years
✔✔DEA Form 224b - ✔✔Affidavit for chain renewal - chain operates under single
registration
✔✔DEA Form 224c - ✔✔Modification of Registration for Online Pharmacies
✔✔DEA Form 225 - ✔✔New application - Manufacturer, distributor, researcher, lab,
importer, exporter
✔✔DEA Form 363 - ✔✔New application - Narcotic Treatment Programs - methadone
maintenance and detox
✔✔DEA Form 510 - ✔✔New application - Domestic Chemical - precursor chemicals
used in manufacture of CS
✔✔DEA Form 222a - ✔✔Order form for 222 Forms
✔✔Examples of CI - ✔✔marijuana, ecstasy, PCP, heroin, LSD, peyote, Salvia (FL)
✔✔Examples of CII - ✔✔Cocaine, dilaudid, Demerol, oxycontin, sublimaze, tylox,
Dexedrine, Ritalin, pentobarbital, MS Contin, Codeine, amphetamine
✔✔Examples of CIII - ✔✔buprenorphine, anabolic steroids, oxandrin, testosterone,
ketamine, didrex, suboxone, Tylenol with Codeine, fiorinal (fioricet is non controlled)
** RULE of three: generally the quantities are evenly divisible by 3 (not morphine and
opium)
✔✔Examples of CIV - ✔✔benzodiazepines, sonata, lunesta, soma
✔✔Examples of CV - ✔✔lyrica, robitussin AC, Phenergan with codeine/
SOLUTIONS RATED A+
✔✔Controlled Substance - CII - ✔✔- no refills
- no post dating of Rx
- No Transfers
- 90 day limit max
- oral Rx only in emergency - limits amount - pharmacist writes the Rx (authorization for
emergency dispensing) attaches original when it arrives. Must obtain within 7 days.
- fax Rx only ok if - Home infusion IV for pain, Residents of LTCF, or state licensed
Hospice facility
- Partial fill ok - complete filling in 72 hours - if can't then notify MD and void remainder.
- LTCF partial refills - valid for 60 days from date written. Each fill the RPh must
document date of fill, qty dispensed and qty remaining and sign.
- RPh may not change essential element on Rx: (Drug, Patient, Signature). May change
address, qty, strength, directions (with auth).
- Order on 222 Forms - may also use to transfer to another pharmacy. May use to send
to reverse distributors.
✔✔What pieces of information may a RPh change on a CII Rx? - ✔✔Address, Quantity,
Strength, Directions with authorization from MD
✔✔Controlled Substance - CIII-IV - ✔✔- five refills in six months
- 1 transfer permitted unless share a common database then may transfer as many time
as needed as long as there are refills
- partial fills permitted - don't exceed total quantity or six month duration
- In Florida pharmacists AND interns may transfer controlled substance prescriptions
- may be written, oral or faxed (need original)
- may make any changes with consultation of MD
- no special order form - orders kept readily retrievable
✔✔Controlled Substance - CV - ✔✔- most are available without a prescription and
indicated as cough or antidiarrheal
- Lyrica (pregabalin) requires Rx
✔✔Controlled Substance - CV - Limits - ✔✔120mg Codeine
60mg Dihydrocodeine
30mg ethyl morphine
240mg opium
within a 48 hour period
✔✔SLCPS - ✔✔Schedule Listed Chemical Product
✔✔SLCPS Examples - ✔✔- Ephedrine, pseudoephedrine, phenylpropanolamine
must train staff and keep training records
,sales limits enforced
stored behind counter or in locked cabinet
written or electronic log book maintained
✔✔SLCPS - List 1 Chemicals - ✔✔Drugs involved in the manufacture of a CS
✔✔SLCPS - List 2 Chemicals - ✔✔Solvents involved in the manufacture of a CS
✔✔Is electronic prescribing of Controlled Substances allowed? - ✔✔Yes
✔✔Name the Prescription Filing System Options - ✔✔1. Three separate files: CII, CIII-
V, and non controls
2. Two separate files: CII, CIII-V and non controls - must stamp a red C >1 inch in lower
right corner
3 Two separate files: CII- V, non controls - must stamp CIII-V with a red C in lower right
corner
✔✔How are Controlled Substances Stored? - ✔✔One of three ways:
1. Locked cabinet
2. Dispersed throughout the pharmacy
3. Combination of both
There is no special requirement for CII to be locked up - may be dispersed.
✔✔Do hospitals need to follow label requirements? - ✔✔No
✔✔Can you mail controlled substances? - ✔✔Yes - in US only. Package must be
unmarked regarding contents
✔✔When do you fill out a DEA Form 106 - ✔✔Where there is theft or significant loss of
a controlled substance.
✔✔May Midlevel practitioners prescribe Controlled Substances in Florida? - ✔✔No.
An agent can phone in a prescription at the request of the registrant (ie a receptionist
may call it in) including emergency CII prescriptions.
✔✔Can a Military MD write an Rx for a controlled substance without a DEA number? -
✔✔Yes. Must use Military number. May fill at a community pharmacy.
✔✔Can Hospital Interns and Residents write an Rx for a controlled substance without a
DEA number? - ✔✔Yes. May use the hospital DEA number plus their hospital ID
number at the end. May fill Rx at community pharmacy and would just use the hospital
DEA.
,✔✔Is Central Fill of Controlled Substances permitted? - ✔✔Yes for CIII-V. Local
pharmacy must write date, pharmacist transmitting and Central Fill on the face of
prescription along with Central fill pharmacy name, address, DEA #.
Store records for two years from date of last fill.
✔✔Can you Central Fill CII prescriptions? - ✔✔NO
✔✔What happens when you execute a 222 Form? - ✔✔- Pharmacy places order and
keeps Copy 3
- Copy 1&2 go to the supplier. Supplier fills the order and keeps Copy 1. Completes
copy 1&2 and mails copy 2 to the DEA.
- Pharmacy completes copy 3 upon receipt of order with containers and date received.
** Supplier can endorse form to another if unable to complete the order.
✔✔Controlled Substances Refills? - ✔✔CII - NO
C III-V Yes - 5 in 6 months
✔✔Controlled Substances Transfer between pharmacies? - ✔✔CII - NO
CIII-V - 1 allowed (unless share same database)
✔✔Controlled Substances Transfer of bulk drugs / pharmacies? - ✔✔CII - Requires 222
CIII-V - requires complete invoice
✔✔Controlled Substances - Oral Rx Allowed? - ✔✔CII - In emergency
CIII - V - Yes
✔✔Controlled Substances - Fax Rx Allowed? - ✔✔CII - Yes to prepare but will need
hard copy to dispense
CIII - V - Yes to prepare but will need hard copy to dispense
✔✔Controlled Substances - Electronic Rx Allowed? - ✔✔CII - Yes subject to security
requirments
CIII - V Yes
✔✔Controlled Substances - Partial Fills Allowed? - ✔✔CII - Generally No but may fill
partial if can't supply entire amount. Must complete within 72 hours. Yes for terminally ill
and LTCF but must mark "terminally ill" or "LTCF patient" on prescription
CIII-V - Yes, just not more than qty or 6 month duration.
✔✔Controlled Substances - Inventory Requirements - ✔✔CII - Exact count
CIII - V - estimated count unless bottle holds more than 1000 units then will need an
exact count.
** Initial inventory required then every two years thereafter.
, Inventory must have drug name, strength, dosage form, number of units in each
container, number of containers (written, typed, or printed - kept on site and includes
inventory date and time and opening or close of business).
✔✔DEA Form 41 - ✔✔Documents disposal and destruction of scheduled drugs
✔✔DEA Form 106 - ✔✔Unusual or excessive loss, disappearance or theft
✔✔DEA Form 222 - ✔✔Order CI and CII (can be electronic - CSOS)
✔✔DEA Form 224 - ✔✔New application for Retail pharmacy, hospital, practitioner,
teaching institution, mid level practioner
✔✔DEA Form 224a - ✔✔Renewal application - every 3 years
✔✔DEA Form 224b - ✔✔Affidavit for chain renewal - chain operates under single
registration
✔✔DEA Form 224c - ✔✔Modification of Registration for Online Pharmacies
✔✔DEA Form 225 - ✔✔New application - Manufacturer, distributor, researcher, lab,
importer, exporter
✔✔DEA Form 363 - ✔✔New application - Narcotic Treatment Programs - methadone
maintenance and detox
✔✔DEA Form 510 - ✔✔New application - Domestic Chemical - precursor chemicals
used in manufacture of CS
✔✔DEA Form 222a - ✔✔Order form for 222 Forms
✔✔Examples of CI - ✔✔marijuana, ecstasy, PCP, heroin, LSD, peyote, Salvia (FL)
✔✔Examples of CII - ✔✔Cocaine, dilaudid, Demerol, oxycontin, sublimaze, tylox,
Dexedrine, Ritalin, pentobarbital, MS Contin, Codeine, amphetamine
✔✔Examples of CIII - ✔✔buprenorphine, anabolic steroids, oxandrin, testosterone,
ketamine, didrex, suboxone, Tylenol with Codeine, fiorinal (fioricet is non controlled)
** RULE of three: generally the quantities are evenly divisible by 3 (not morphine and
opium)
✔✔Examples of CIV - ✔✔benzodiazepines, sonata, lunesta, soma
✔✔Examples of CV - ✔✔lyrica, robitussin AC, Phenergan with codeine/
