LMR GEORGETTE’S PMHNP FINAL EXAM 2026/2027
QUESTIONS AND SOLUTIONS RATED A+
✔✔ADHD neurotransmitters - ✔✔decrease in dopamine and norepinephrine
✔✔Tourette's Neurotransmitters - ✔✔dopamine, serotonin, GABA, and glutamate
✔✔What to prescribe for Tourette's - ✔✔Risperdal
✔✔Substance abuse neurotransmitters - ✔✔decrease in opioid neuropeptides
✔✔Alcohol abuse neurotransmitters - ✔✔increase in GABA and dopamine and
decrease in serotonin
✔✔Depression neurotransmitters - ✔✔decrease in serotonin, dopamine, and
norepinephrine
✔✔sleep neurotransmitters - ✔✔low serotonin causes insomnia (Melatonin is pre-
cursor)
✔✔Schizophrenia neurotransmitters - ✔✔increased dopamine and decreased serotonin
✔✔negative symptoms of schizophrenia - ✔✔disturbance of affect, blunting (severe
reduction in the intensity of affect expression), flat affect, inappropriate affect (might
laugh hysterically while describing someones death)
✔✔positive symptoms of schizophrenia - ✔✔Delusions of reference, delusions of
persecution, delusions of grandeur, thought broadcasting, though insertion,
hallucinations, disorganized thought, disorganized behavior, catatonia
✔✔Side effects of atypical antipsychotics - ✔✔Risk of metabolic syndrome: increased
weight, blood glucose, triglycerides, and insulin resistance
✔✔Zyprexa (Olanzapine) side effect - ✔✔Excessive weight gain
✔✔Seroquel side effects - ✔✔weight gain and sedation; cataracts (assess with slit
lamp)
✔✔Thorazine (chlorpromazine) - ✔✔corneal deposits
✔✔Geodon (ziprasidone) - ✔✔weight neutral, take with food, monitor for QT
prolongation
✔✔Latuda (lurasidone) - ✔✔eat with med 360 calories
, ✔✔Risperdal and Reglan - ✔✔Reglan is a D2 dopamine antagonist and should be
avoided with Risperdal for 2 hours. It decreases the absorption of the Risperdal.
✔✔First line antipsychotic in children - ✔✔Risperdal (max 3 mg/day)
✔✔arcus senilis - ✔✔gray-white arc or circle around the limbus of the iris that is
common with aging; hyperlipidemia
✔✔Protection of ischemic injuries - ✔✔atypical antipsychotics
✔✔Ages of Schizophrenia - ✔✔18-25 males
25-35 females
✔✔Why dose cimetidine, zantac, and omeprazole 2 hours apart from Risperdal? -
✔✔They are inhibitors and will decrease the absorption of Risperdal in liver
✔✔What alpha 2 delta ligands are approved for neuropathic pain tx? - ✔✔Lyrica and
gabapentin
✔✔Celexa and Lexapro side effect - ✔✔Prolonged QT interval
✔✔Effexor side effect - ✔✔elevated bp
✔✔false positives - ✔✔benzos- zoloft
✔✔what to avoid with MAOIs - ✔✔Tyramine (aged cheese, wine, pickled herring)
✔✔What can happen when TCAs and MAOIs are combined? - ✔✔Increased
norepinephrine causing a hypertensive crisis (flushing, explosive headache in the back
of head)
✔✔How to treat hypertensive crisis from MAOI and TCA combo - ✔✔Phentolamine
✔✔What is 1st line antidepressant for children? - ✔✔Prozac
✔✔Tx OCD in kids - ✔✔Zoloft
✔✔How long to wait between MAOI and SSRI - ✔✔14 days
✔✔How long is the wash-out period between MAOI and Prozac? - ✔✔5 weeks
QUESTIONS AND SOLUTIONS RATED A+
✔✔ADHD neurotransmitters - ✔✔decrease in dopamine and norepinephrine
✔✔Tourette's Neurotransmitters - ✔✔dopamine, serotonin, GABA, and glutamate
✔✔What to prescribe for Tourette's - ✔✔Risperdal
✔✔Substance abuse neurotransmitters - ✔✔decrease in opioid neuropeptides
✔✔Alcohol abuse neurotransmitters - ✔✔increase in GABA and dopamine and
decrease in serotonin
✔✔Depression neurotransmitters - ✔✔decrease in serotonin, dopamine, and
norepinephrine
✔✔sleep neurotransmitters - ✔✔low serotonin causes insomnia (Melatonin is pre-
cursor)
✔✔Schizophrenia neurotransmitters - ✔✔increased dopamine and decreased serotonin
✔✔negative symptoms of schizophrenia - ✔✔disturbance of affect, blunting (severe
reduction in the intensity of affect expression), flat affect, inappropriate affect (might
laugh hysterically while describing someones death)
✔✔positive symptoms of schizophrenia - ✔✔Delusions of reference, delusions of
persecution, delusions of grandeur, thought broadcasting, though insertion,
hallucinations, disorganized thought, disorganized behavior, catatonia
✔✔Side effects of atypical antipsychotics - ✔✔Risk of metabolic syndrome: increased
weight, blood glucose, triglycerides, and insulin resistance
✔✔Zyprexa (Olanzapine) side effect - ✔✔Excessive weight gain
✔✔Seroquel side effects - ✔✔weight gain and sedation; cataracts (assess with slit
lamp)
✔✔Thorazine (chlorpromazine) - ✔✔corneal deposits
✔✔Geodon (ziprasidone) - ✔✔weight neutral, take with food, monitor for QT
prolongation
✔✔Latuda (lurasidone) - ✔✔eat with med 360 calories
, ✔✔Risperdal and Reglan - ✔✔Reglan is a D2 dopamine antagonist and should be
avoided with Risperdal for 2 hours. It decreases the absorption of the Risperdal.
✔✔First line antipsychotic in children - ✔✔Risperdal (max 3 mg/day)
✔✔arcus senilis - ✔✔gray-white arc or circle around the limbus of the iris that is
common with aging; hyperlipidemia
✔✔Protection of ischemic injuries - ✔✔atypical antipsychotics
✔✔Ages of Schizophrenia - ✔✔18-25 males
25-35 females
✔✔Why dose cimetidine, zantac, and omeprazole 2 hours apart from Risperdal? -
✔✔They are inhibitors and will decrease the absorption of Risperdal in liver
✔✔What alpha 2 delta ligands are approved for neuropathic pain tx? - ✔✔Lyrica and
gabapentin
✔✔Celexa and Lexapro side effect - ✔✔Prolonged QT interval
✔✔Effexor side effect - ✔✔elevated bp
✔✔false positives - ✔✔benzos- zoloft
✔✔what to avoid with MAOIs - ✔✔Tyramine (aged cheese, wine, pickled herring)
✔✔What can happen when TCAs and MAOIs are combined? - ✔✔Increased
norepinephrine causing a hypertensive crisis (flushing, explosive headache in the back
of head)
✔✔How to treat hypertensive crisis from MAOI and TCA combo - ✔✔Phentolamine
✔✔What is 1st line antidepressant for children? - ✔✔Prozac
✔✔Tx OCD in kids - ✔✔Zoloft
✔✔How long to wait between MAOI and SSRI - ✔✔14 days
✔✔How long is the wash-out period between MAOI and Prozac? - ✔✔5 weeks
