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Samenvatting Bacteriologie - Allesomvattende Tabel

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Deze tabel behandelt de bacteriologische classificatie en antibioticagevoeligheid zoals onderwezen in de cursus Microbiologie en infectieziekten aan KU Leuven. Het document gaat dieper in op grampositive en gramnegative bacteriën, mycoplasma's, treponemataceae, mycobacteriën en intracellulaire pathogenen, met specifieke aandacht voor hun celwandstructuur en intrinsieke resistentiemechanismen. Ideaal voor examenvoorbereiding en effectieve herhaling van de belangrijkste bacteriële groepen en hun standaardbehandelingen.

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AEROOB EN FACULTATIEF ANAEROOB

GRAM +
Bacterie Ziektebeeld Kenmerken Behandeling
S. Aureus -Huid en wekedelen -Facultatief anaeroob PSSA: penicilline
 atopische dermatitis, -Biofilm MSSA: cefazoline
panorychia, furunkel -Coagulase negatief MRSA: vancomyc
 impetigo -Invasines
 abces  Proteasen
-Invasief  Hyaluronidase
 endocarditis -Immuunontwijking
 osteomyelitis  Capsule
 pneumonie  Proteïne A (SpA)
 sepsis -Toxines
 wondinfecties  TSST-1= super-AG
PVL = porie, abces
 Exfoliatief = SSSS,
gericht op desmogleïne 1
 Enterotoxine = hitte
 alfa-toxine = lysis,
abces
-Resistentie
 MRSA
S. Epidermidis Vreemd lichaam -Facultatief anaeroob Flucloxacilline/
-Katheters vancomycine
-Prothesen
-Biofilm
-Coagulase-negatief
S. Saprophyticus Urinair -Uropathogeen Nitrofurantoïne
-Coagulasenegatief
Str. Pyogenes -Keel en weke delen = GAS Penicilline
 faryngitis -ß-hemolyse Amoxicilline
 scarlet fever, erysipelas, -Invasines
cellulitis  Hyaluronidase
 impetigo  Streptokinase
 TSS door exotoxins -Immuunontwijking
 post-infectieuze  M-eiwit
complicaties  Capsule
-Kraambedkoorts!  C5a peptidase
 DNAses
-Toxines
 SLS = streptolysine S
 SLO = streptolysine O
 SPE = exotoxine
Str. Agalactiae -Neonatale meningitis = GBS Penicilline
-Meningitis -ß-hemolyse Amoxicilline
-Normale vaginale flora
Enterococcus Endocarditis (opportunistisch) ß-lactam gevoelig
faecalis
Enterococcus Endocarditis (opportunistisch) ß-lactam resistent Linezolide
faecium VRE Daptomycine
Str. Pneumoniae -niet-invasief -Polysacharidencapsule Amoxicilline
 otitis media -Toxine: pneumolysine: Ceftriaxone
 niet-invasieve pneumonie poriën
 sinusitis -Opp-eiwitten
-invasief -OPSI (bij asplenia)
 bacteriële meningitis -Vaccin: PPV of PCV

,  bacteriëmie -Resistentie:
 pneumokokkenpneumonie  Macroliden
 Penicilline
 Fluoroquinolonen
Str. Viridans -Tandplaque -Alfa-hemolytisch Penicilline
-Vreemd lichaam -Normale mondflora Ceftriaxone
-Endocarditis
Bacillus anthraxis Cutane anthrax -Zoönose (koeien) Ciprofloxacine
-Eschar Doxycycline
-Miltvuur
-Directe transmissie
-Vaccin: levend verzwakt
Corynebacterium Cutane drifterie -Zoönose
ulcerans - Exotoxine
(drifterietoxine), via
bacteriofaag
-Ongenezende zweren
-Grijsachtig
pseudomembraan
Corynebacterium Acne -Bij overgroei Penicilline
acnes -Lipofiel Clindamycine
-Expressie PIC Rifampicine
Corynebacterium Respiratoire drifterie -Exotoxine Drifterie-antitoxin
diptheriae (drifterietoxine), via Erythromycine
bacteriofaag
-Pseudomembraan
-Vaccin (toxoïd)
-20% heeft hartproblemen
Listeria -Voedselinfectie -Omgevingssaprofyt Ampicilline +
monocytogenes -Meningitis -Lage temp gentamicine
-Intra-uteriene infectie -Ongepasteuriseerde melk
-Liseriolsine O
Erysipelothrix Cellulitis (erysipeloïde) -Zoönose Penicilline
rhusiopathiae -Langzaam groeiend
-Alfa-hemolytisch
Lactobacillus sp. Bacteriëmie -Productie melkzuur: pH
(immuungecompromitteerd) daalt
-Vaginale flora
-Bescherming
Gardnerella Bacteriële vaginose -Clue cells Metronidazol
-Productie vetzuren en
amines
-vaginale pH > 4.5
-Grijze afscheiding
-Gram-variabel
Nocardia Opportunistisch -Partieel zuurvaste Trimethoprim-
 long bacterie sulfametoxazol
 huid -Oppervlakkige infecties
-Vertakt zoals
actinomycetes

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