2
Maryville University Advanced Pathophysiology Exam 2 with || || || || || || ||
verified detailed answers || ||
Which cancer originates from connective tissue? - ✔✔osteogenic sarcoma
|| || || || || || || ||
carcinoma refers to abnormal cell proliferation originating from which origin? -
|| || || || || || || || || || ||
✔✔epithelial cells ||
carcinoma in situ is characterized by which changes? - ✔✔Cells remain localized in the
|| || || || || || || || || || || || || ||
glandular or squamous cells || || ||
which term is used to describe a muscle cell showing a reduced ability to form new muscle
|| || || || || || || || || || || || || || || || ||
while appearing highly disorganized? - ✔✔anaplasia
|| || || || ||
what are tumor cell markers? - ✔✔hormones, enzymes, antigens and antibodies that are
|| || || || || || || || || || || || ||
produced by cancer cells || || ||
the function of the tumor cell marker is to: - ✔✔screen individuals at high risk for cancer
|| || || || || || || || || || || || || || || ||
which statement supports the hypothesis that intestinal polyps are benign neoplasms and
|| || || || || || || || || || || ||
the first stage in the development of colon cancer? - ✔✔an accumulation of mutations in
|| || || || || || || || || || || || || || ||
specific genes is required for the development of cancer
|| || || || || || || ||
autocrine stimulation is the ability of cancer cells to: - ✔✔secrete growth factors that
|| || || || || || || || || || || || || ||
stimulate their own growth || || ||
apoptosis is: - ✔✔normal mechanism for cells to self-destruct when growth is excessive
|| || || || || || || || || || || ||
, 2
many cancers create a mutation of ras. ras is a (an): - ✔✔intracellular-signaling protein that
|| || || || || || || || || || || || || || ||
regulates cell growth || ||
oncogenes are genes that are capable of: - ✔✔undergoing mutation that directs the
|| || || || || || || || || || || || ||
synthesis of proteins to accelerate the rate of tissue proliferation
|| || || || || || || || ||
Burkitt lymphomas designate a chromosome that has a piece of chromosome 8 fused to a
|| || || || || || || || || || || || || || ||
piece of chromosome 14. This is an example of which mutation of normal genes to
|| || || || || || || || || || || || || || ||
oncogenes? - ✔✔chromosome translocation || || ||
in childhood neuroblastoma, the N-myc oncogene undergoes which type of mutation of
|| || || || || || || || || || || ||
normal gene to oncogene? - ✔✔gene amplification
|| || || || || ||
what aberrant change causes the abnormal growth in retinoblastoma? - ✔✔the tumor
|| || || || || || || || || || || ||
suppressor gene is turned off || || || ||
two "hits" are required to inactivate tumor-suppressor genes because: - ✔✔each allele must
|| || || || || || || || || || || || ||
be altered, and each person has two copies, or alleles of each gene: one from each parent
|| || || || || || || || || || || || || || || ||
the ras gene converts from a proto-oncogene to an oncogene by: - ✔✔altering one or more
|| || || || || || || || || || || || || || || ||
nucleotide base pairs || ||
how do cancer cells use the enzyme telomerase? - ✔✔to switch on the telomerase to enable
|| || || || || || || || || || || || || || || ||
cells to divide indefinitely
|| || ||
what are characteristics of a benign tumor? - ✔✔they include the suffix -oma
|| || || || || || || || || || || ||
Maryville University Advanced Pathophysiology Exam 2 with || || || || || || ||
verified detailed answers || ||
Which cancer originates from connective tissue? - ✔✔osteogenic sarcoma
|| || || || || || || ||
carcinoma refers to abnormal cell proliferation originating from which origin? -
|| || || || || || || || || || ||
✔✔epithelial cells ||
carcinoma in situ is characterized by which changes? - ✔✔Cells remain localized in the
|| || || || || || || || || || || || || ||
glandular or squamous cells || || ||
which term is used to describe a muscle cell showing a reduced ability to form new muscle
|| || || || || || || || || || || || || || || || ||
while appearing highly disorganized? - ✔✔anaplasia
|| || || || ||
what are tumor cell markers? - ✔✔hormones, enzymes, antigens and antibodies that are
|| || || || || || || || || || || || ||
produced by cancer cells || || ||
the function of the tumor cell marker is to: - ✔✔screen individuals at high risk for cancer
|| || || || || || || || || || || || || || || ||
which statement supports the hypothesis that intestinal polyps are benign neoplasms and
|| || || || || || || || || || || ||
the first stage in the development of colon cancer? - ✔✔an accumulation of mutations in
|| || || || || || || || || || || || || || ||
specific genes is required for the development of cancer
|| || || || || || || ||
autocrine stimulation is the ability of cancer cells to: - ✔✔secrete growth factors that
|| || || || || || || || || || || || || ||
stimulate their own growth || || ||
apoptosis is: - ✔✔normal mechanism for cells to self-destruct when growth is excessive
|| || || || || || || || || || || ||
, 2
many cancers create a mutation of ras. ras is a (an): - ✔✔intracellular-signaling protein that
|| || || || || || || || || || || || || || ||
regulates cell growth || ||
oncogenes are genes that are capable of: - ✔✔undergoing mutation that directs the
|| || || || || || || || || || || || ||
synthesis of proteins to accelerate the rate of tissue proliferation
|| || || || || || || || ||
Burkitt lymphomas designate a chromosome that has a piece of chromosome 8 fused to a
|| || || || || || || || || || || || || || ||
piece of chromosome 14. This is an example of which mutation of normal genes to
|| || || || || || || || || || || || || || ||
oncogenes? - ✔✔chromosome translocation || || ||
in childhood neuroblastoma, the N-myc oncogene undergoes which type of mutation of
|| || || || || || || || || || || ||
normal gene to oncogene? - ✔✔gene amplification
|| || || || || ||
what aberrant change causes the abnormal growth in retinoblastoma? - ✔✔the tumor
|| || || || || || || || || || || ||
suppressor gene is turned off || || || ||
two "hits" are required to inactivate tumor-suppressor genes because: - ✔✔each allele must
|| || || || || || || || || || || || ||
be altered, and each person has two copies, or alleles of each gene: one from each parent
|| || || || || || || || || || || || || || || ||
the ras gene converts from a proto-oncogene to an oncogene by: - ✔✔altering one or more
|| || || || || || || || || || || || || || || ||
nucleotide base pairs || ||
how do cancer cells use the enzyme telomerase? - ✔✔to switch on the telomerase to enable
|| || || || || || || || || || || || || || || ||
cells to divide indefinitely
|| || ||
what are characteristics of a benign tumor? - ✔✔they include the suffix -oma
|| || || || || || || || || || || ||
