APEA- Orthopedics PHARM Exam Questions with Correct Answers
Question 1:
Probenecid, used in the treatment of gout, works by:
-decreasing the tubular secretion of uric acid and inhibiting the secretion of penicillin.
-destroying uric acid crystals in the renal tubular system and slowing the metabolism of
penicillin.
-increasing the urinary excretion of uric acid and inhibiting the secretion of penicillin.
-promoting the bactericidal activity of penicillin and breaking down uric acid.
Answer:
increasing the urinary
Question 2:
Before prescribing Dantrolene (Dantrium), a peripherally-acting muscle relaxant, obtain a
baseline serum:
blood urea nitrogen (BUN). complete blood count (CBC).
Answer:
excretion of uric acid and inhibiting the secretion of penicillin. calcium level.
Question 3:
liver function test.
Answer:
Liver function test
Question 4:
Which of the following is NOT a reason to discontinue allopurinol (Zyloprim)? Acute gout
exacerbation
Dysuria Jaundice Skin rash
Answer:
acute gout exacerbation
Question 5:
Patients should be instructed to take tizanidine (Zanaflex): daily, not exceeding 16 mg daily.
before bedtime only. with food only.
Answer:
consistently fasting or nonfasting.
,Question 6:
The maximum recommended daily dose of acetaminophen (Tylenol) for the management of
pain associated with a clavicular fracture is:
gram.
grams.
Answer:
do not switch method of administrations- will change absorption of drug 3 grams.
Question 7:
4 grams. occurrence of:
hypotonia. urinary retention.
Answer:
4 grams
Patients should be instructed to avoid abrupt withdrawal of baclofen (Lioresal) to prevent the
seizures.
Question 8:
hypothermia.
Answer:
seizures
Question 9:
Ketorolac (Toradol), a nonsteroidal anti-inflammatory drug, is: indicated for short-term
treatment of moderate pain.
not known to cause renal insufficiency.
indicated for the treatment of moderate pain in children. indicated for pain following coronary
artery bypass graft surgery.
Answer:
indicated for short-term treatment of
Question 10:
When corticosteroids are used in combination with nonsteroidal anti-inflammatory drugs
(NSAIDs), patients may develop:
osteoarthritis.
Answer:
moderate pain.
gastrointestinal bleeding.
, Question 11:
hypoglycemia.
Answer:
gastrointestinal bleeding
Patients may develop increased gastrointestinal symptoms and bleeding because both products
Question 12:
Which of the following is NOT classified as a muscle relaxant: metaxalone (Skelaxin).
cyclobenzaprine (Amrix).
Answer:
diminish the gastroprotective effects of prostaglandins. methocarbamol (Robaxin).
Question 13:
tramadol (Ultram).
Answer:
tramadol (Ultram)
Question 14:
Baclofen (Lioresal), a centrally-acting muscle relaxant, is indicated for the treatment of: restless
leg syndrome.
intermittent claudication. spasticity.
essential tremor.
Answer:
spasticity
Baclofen (Lioresal) is indicated for the treatment of spasticity that may be related to multiple
sclerosis, traumatic brain injury, encephalitis, and spinal cord injury. Trigeminal neuralgia,
nystagmus, hiccups,
Question 15:
Acetaminophen (Tylenol) does NOT produce:
analgesia. antipyresis effects.
Answer:
alcohol abstinence and gastroesophageal reflux are off-label uses. potentiated opioid analgesia.
Question 16:
anti-inflammatory activity.
Answer:
anti-inflammatory activity
Question 1:
Probenecid, used in the treatment of gout, works by:
-decreasing the tubular secretion of uric acid and inhibiting the secretion of penicillin.
-destroying uric acid crystals in the renal tubular system and slowing the metabolism of
penicillin.
-increasing the urinary excretion of uric acid and inhibiting the secretion of penicillin.
-promoting the bactericidal activity of penicillin and breaking down uric acid.
Answer:
increasing the urinary
Question 2:
Before prescribing Dantrolene (Dantrium), a peripherally-acting muscle relaxant, obtain a
baseline serum:
blood urea nitrogen (BUN). complete blood count (CBC).
Answer:
excretion of uric acid and inhibiting the secretion of penicillin. calcium level.
Question 3:
liver function test.
Answer:
Liver function test
Question 4:
Which of the following is NOT a reason to discontinue allopurinol (Zyloprim)? Acute gout
exacerbation
Dysuria Jaundice Skin rash
Answer:
acute gout exacerbation
Question 5:
Patients should be instructed to take tizanidine (Zanaflex): daily, not exceeding 16 mg daily.
before bedtime only. with food only.
Answer:
consistently fasting or nonfasting.
,Question 6:
The maximum recommended daily dose of acetaminophen (Tylenol) for the management of
pain associated with a clavicular fracture is:
gram.
grams.
Answer:
do not switch method of administrations- will change absorption of drug 3 grams.
Question 7:
4 grams. occurrence of:
hypotonia. urinary retention.
Answer:
4 grams
Patients should be instructed to avoid abrupt withdrawal of baclofen (Lioresal) to prevent the
seizures.
Question 8:
hypothermia.
Answer:
seizures
Question 9:
Ketorolac (Toradol), a nonsteroidal anti-inflammatory drug, is: indicated for short-term
treatment of moderate pain.
not known to cause renal insufficiency.
indicated for the treatment of moderate pain in children. indicated for pain following coronary
artery bypass graft surgery.
Answer:
indicated for short-term treatment of
Question 10:
When corticosteroids are used in combination with nonsteroidal anti-inflammatory drugs
(NSAIDs), patients may develop:
osteoarthritis.
Answer:
moderate pain.
gastrointestinal bleeding.
, Question 11:
hypoglycemia.
Answer:
gastrointestinal bleeding
Patients may develop increased gastrointestinal symptoms and bleeding because both products
Question 12:
Which of the following is NOT classified as a muscle relaxant: metaxalone (Skelaxin).
cyclobenzaprine (Amrix).
Answer:
diminish the gastroprotective effects of prostaglandins. methocarbamol (Robaxin).
Question 13:
tramadol (Ultram).
Answer:
tramadol (Ultram)
Question 14:
Baclofen (Lioresal), a centrally-acting muscle relaxant, is indicated for the treatment of: restless
leg syndrome.
intermittent claudication. spasticity.
essential tremor.
Answer:
spasticity
Baclofen (Lioresal) is indicated for the treatment of spasticity that may be related to multiple
sclerosis, traumatic brain injury, encephalitis, and spinal cord injury. Trigeminal neuralgia,
nystagmus, hiccups,
Question 15:
Acetaminophen (Tylenol) does NOT produce:
analgesia. antipyresis effects.
Answer:
alcohol abstinence and gastroesophageal reflux are off-label uses. potentiated opioid analgesia.
Question 16:
anti-inflammatory activity.
Answer:
anti-inflammatory activity
