Nightingale College BSN 315
PHARMACOLOGY 2026/2027
HESI PRACTICE QUESTIONS
UPDATE 200Q&A (VERIFIED)
GUARANTEED PASS
A client with giardiasis is taking metronidazole 2 grams PO. Which information should the nurse
include in the client's instruction?
a) Notify the clinic of any changes in the color of urine.
b) Avoid overexposure to the sun.
c) Stop the medication after the diarrhea resolves.
d) Take the medication with food.
d) Take the medication with food.
Which action is most important for the nurse to implement prior to the administration of the
antiarrhythmic drug adenosine?
a) Assess pupillary response to light.
b) Instruct the client that facial flushing may occur.
c) Apply continuous cardiac monitoring.
d) Request that family members leave the room.
c) Apply continuous cardiac monitoring.
Which instruction(s) should the nurse give to a female client who just received a prescription for oral
metronidazole for the treatment of Trichomonas vaginalis?
a) Increase fluid intake, especially cranberry juice.
b) Do not abruptly discontinue the medication; taper use.
c) Check blood pressure daily to detect hypertension.
d) Avoid drinking alcohol while taking this medication.
e) Use condoms until treatment is completed.
f) Ensure that all sexual partners are treated at the same time.
,a) Increase fluid intake, especially cranberry juice.
d) Avoid drinking alcohol while taking this medication.
e) Use condoms until treatment is completed.
f) Ensure that all sexual partners are treated at the same time.
Which nursing intervention is most important when caring for a client receiving the antimetabolite
cytosine arabinoside for chemotherapy?
a) Hydrate the client with IV fluids before and after infusion.
b) Assess the client for numbness and tingling of extremities.
c) Inspect the client's oral mucosa for ulcerations.
d) Monitor the client's urine pH for increased acidity.
c) Inspect the client's oral mucosa for ulcerations.
After abdominal surgery, a male client is prescribed low molecular weight heparin (LMWH). During
the administration of the medication, the client asks the nurse why he is receiving this medication.
Which is the best response for the nurse to provide?
a) This medication is a blood thinner given to prevent blood clot formation.
b) This medication enhances antibiotics to prevent infection.
c) This medication dissolves any clots that develop in the legs.
d) This abdominal injection assists in the healing of the abdominal wound.
a) This medication is a blood thinner given to prevent blood clot formation.
A client is being treated for hyperthyroidism with propylthiouracil. The nurse knows that the action of
this drug is to?
a) Decrease the amount of thyroid-stimulating hormone circulating in the blood.
b) Increase the amount of thyroid-stimulating hormone circulating in the blood.
c) Increase the amount of T4 and decrease the amount of T3 produced by the thyroid.
d) Inhibit synthesis of T3 and T4 by the thyroid gland.
d) Inhibit synthesis of T3 and T4 by the thyroid gland.
Following the administration of sublingual nitroglycerin to a client experiencing an acute anginal
attack, which assessment finding indicates to the nurse that the desired effect has been achieved?
a) Client states chest pain is relieved.
b) Client's pulse decreases from 120 to 90.
c) Client's systolic blood pressure decreases from 180 to 90.
d) Client's SaO₂ level increases from 92% to 96%.
a) Client states chest pain is relieved.
,A client is receiving digoxin for the onset of supraventricular tachycardia (SVT). Which laboratory
finding should the nurse identify that places this client at risk?
a) Hypokalemia.
b) Hyponatremia.
c) Hypercalcemia.
d) Low uric acid levels.
a) Hypokalemia.
A client with hyperlipidemia receives a prescription for niacin. Which client teaching is most important
for the nurse to provide?
a) Expected duration of flushing.
b) Symptoms of hyperglycemia.
c) Diets that minimize GI irritation.
d) Comfort measures for pruritus.
a) Expected duration of flushing.
A female client with rheumatoid arthritis takes ibuprofen 600 mg PO 4 times a day. To prevent
gastrointestinal bleeding, misoprostol 100 mcg PO is prescribed. Which information is most important
for the nurse to include in client teaching?
a) Use contraception during intercourse.
b) Ensure the misoprostol is taken on an empty stomach
c) Encourage oral fluid intake to prevent constipation.
d) Take misoprostol 30 minutes prior to ibuprofen.
a) Use contraception during intercourse.
A client with coronary artery disease who is taking digoxin receives a new prescription for
atorvastatin. Two weeks after initiation of the prescription, the nurse assesses the client. Which
finding requires the most immediate intervention?
a) Heartburn.
b) Headache.
c) Constipation.
d) Vomiting.
d) Vomiting.
, The healthcare provider prescribes digitalis for a client diagnosed with heart failure. Which
intervention should the nurse implement prior to administering the digitalis?
a) Observe respiratory rate and depth.
b) Assess the serum potassium level.
c) Obtain the client's blood pressure.
d) Monitor the serum glucose level.
b) Assess the serum potassium level.
While taking a nursing history, the client states, "I am allergic to penicillin." Which related allergy to
another type of antiinfective agent should the nurse ask the client about when taking the nursing
history?
:a) Aminoglycosides
b) Cephalosporins
c) Sulfonamides
d) Tetracyclines
b) Cephalosporins
A client with peptic ulcer disease receives a new prescription for cimetidine. Which statement
provided by the client requires additional instruction by the nurse?
A Decrease cigarette use to a pack per day.
B Notify the healthcare provider of lethargy.
C T ake the medication an hour after antacids.
D Monitor for any signs of sexual dysfunction.
A Decrease cigarette use to a pack per day.
Which intervention is most important for the nurse to implement for a client with type 2 diabetes
mellitus (DM) who is receiving insulin lispro?
A Check blood glucose levels every six hours.
B Assess for hypoglycemia between meals.
C Provide meals at the same time this insulin is given.
D Keep an oral liquid or glucose source available.
C Provide meals at the same time this insulin is given.
PHARMACOLOGY 2026/2027
HESI PRACTICE QUESTIONS
UPDATE 200Q&A (VERIFIED)
GUARANTEED PASS
A client with giardiasis is taking metronidazole 2 grams PO. Which information should the nurse
include in the client's instruction?
a) Notify the clinic of any changes in the color of urine.
b) Avoid overexposure to the sun.
c) Stop the medication after the diarrhea resolves.
d) Take the medication with food.
d) Take the medication with food.
Which action is most important for the nurse to implement prior to the administration of the
antiarrhythmic drug adenosine?
a) Assess pupillary response to light.
b) Instruct the client that facial flushing may occur.
c) Apply continuous cardiac monitoring.
d) Request that family members leave the room.
c) Apply continuous cardiac monitoring.
Which instruction(s) should the nurse give to a female client who just received a prescription for oral
metronidazole for the treatment of Trichomonas vaginalis?
a) Increase fluid intake, especially cranberry juice.
b) Do not abruptly discontinue the medication; taper use.
c) Check blood pressure daily to detect hypertension.
d) Avoid drinking alcohol while taking this medication.
e) Use condoms until treatment is completed.
f) Ensure that all sexual partners are treated at the same time.
,a) Increase fluid intake, especially cranberry juice.
d) Avoid drinking alcohol while taking this medication.
e) Use condoms until treatment is completed.
f) Ensure that all sexual partners are treated at the same time.
Which nursing intervention is most important when caring for a client receiving the antimetabolite
cytosine arabinoside for chemotherapy?
a) Hydrate the client with IV fluids before and after infusion.
b) Assess the client for numbness and tingling of extremities.
c) Inspect the client's oral mucosa for ulcerations.
d) Monitor the client's urine pH for increased acidity.
c) Inspect the client's oral mucosa for ulcerations.
After abdominal surgery, a male client is prescribed low molecular weight heparin (LMWH). During
the administration of the medication, the client asks the nurse why he is receiving this medication.
Which is the best response for the nurse to provide?
a) This medication is a blood thinner given to prevent blood clot formation.
b) This medication enhances antibiotics to prevent infection.
c) This medication dissolves any clots that develop in the legs.
d) This abdominal injection assists in the healing of the abdominal wound.
a) This medication is a blood thinner given to prevent blood clot formation.
A client is being treated for hyperthyroidism with propylthiouracil. The nurse knows that the action of
this drug is to?
a) Decrease the amount of thyroid-stimulating hormone circulating in the blood.
b) Increase the amount of thyroid-stimulating hormone circulating in the blood.
c) Increase the amount of T4 and decrease the amount of T3 produced by the thyroid.
d) Inhibit synthesis of T3 and T4 by the thyroid gland.
d) Inhibit synthesis of T3 and T4 by the thyroid gland.
Following the administration of sublingual nitroglycerin to a client experiencing an acute anginal
attack, which assessment finding indicates to the nurse that the desired effect has been achieved?
a) Client states chest pain is relieved.
b) Client's pulse decreases from 120 to 90.
c) Client's systolic blood pressure decreases from 180 to 90.
d) Client's SaO₂ level increases from 92% to 96%.
a) Client states chest pain is relieved.
,A client is receiving digoxin for the onset of supraventricular tachycardia (SVT). Which laboratory
finding should the nurse identify that places this client at risk?
a) Hypokalemia.
b) Hyponatremia.
c) Hypercalcemia.
d) Low uric acid levels.
a) Hypokalemia.
A client with hyperlipidemia receives a prescription for niacin. Which client teaching is most important
for the nurse to provide?
a) Expected duration of flushing.
b) Symptoms of hyperglycemia.
c) Diets that minimize GI irritation.
d) Comfort measures for pruritus.
a) Expected duration of flushing.
A female client with rheumatoid arthritis takes ibuprofen 600 mg PO 4 times a day. To prevent
gastrointestinal bleeding, misoprostol 100 mcg PO is prescribed. Which information is most important
for the nurse to include in client teaching?
a) Use contraception during intercourse.
b) Ensure the misoprostol is taken on an empty stomach
c) Encourage oral fluid intake to prevent constipation.
d) Take misoprostol 30 minutes prior to ibuprofen.
a) Use contraception during intercourse.
A client with coronary artery disease who is taking digoxin receives a new prescription for
atorvastatin. Two weeks after initiation of the prescription, the nurse assesses the client. Which
finding requires the most immediate intervention?
a) Heartburn.
b) Headache.
c) Constipation.
d) Vomiting.
d) Vomiting.
, The healthcare provider prescribes digitalis for a client diagnosed with heart failure. Which
intervention should the nurse implement prior to administering the digitalis?
a) Observe respiratory rate and depth.
b) Assess the serum potassium level.
c) Obtain the client's blood pressure.
d) Monitor the serum glucose level.
b) Assess the serum potassium level.
While taking a nursing history, the client states, "I am allergic to penicillin." Which related allergy to
another type of antiinfective agent should the nurse ask the client about when taking the nursing
history?
:a) Aminoglycosides
b) Cephalosporins
c) Sulfonamides
d) Tetracyclines
b) Cephalosporins
A client with peptic ulcer disease receives a new prescription for cimetidine. Which statement
provided by the client requires additional instruction by the nurse?
A Decrease cigarette use to a pack per day.
B Notify the healthcare provider of lethargy.
C T ake the medication an hour after antacids.
D Monitor for any signs of sexual dysfunction.
A Decrease cigarette use to a pack per day.
Which intervention is most important for the nurse to implement for a client with type 2 diabetes
mellitus (DM) who is receiving insulin lispro?
A Check blood glucose levels every six hours.
B Assess for hypoglycemia between meals.
C Provide meals at the same time this insulin is given.
D Keep an oral liquid or glucose source available.
C Provide meals at the same time this insulin is given.
