MARYVILLE PHARMACOLOGY UPDATED EXAMS
TEST PAPER 2026 QUESTIONS AND ANSWERS SURE
A+
✔✔atropine- indications - ✔✔*symptomatic bradycardia (sinus, junctional, AV blocks,
causing significant hypotension, ventricular ectopy, angina, etc.)
*organphosphate poisoning
* RSI in peds
*beta blocker and calcium channel blocker overdose
✔✔atropine- contraindications - ✔✔*tachycardia
*HTN
*hypothermic bradycardia
*narrow angle glaucoma
✔✔atropine adverse reactions - ✔✔drowsiness, confusion, HA, tachycardia,
palpitations, dysrhythmias, N/V, paradoxical bradycardia if pushed too slowly or given in
low doses
✔✔atropine special considerations to know - ✔✔Pregnancy category C
paradoxical bradycardia can occur with doses lower than 0.1 mg.
, ✔✔Types of cholinergic receptors - ✔✔1. Muscarinic (G protein linked)
-M2- health and smooth muscle
-M3- glands and endothelium
-M1,4,5-nerves
2. Nicotinic receptors (ion channel mediated)
- Nm-Skeletal muscle
-Nn- autonomic ganglion cells
**activated by acetlycholine
✔✔What neurotransmitter do cholinergics mimic? - ✔✔acetycholine
✔✔direct acting cholinergics - ✔✔pilocar (pilocarpine)
reglan (metoclopramide)
Urecholine (bethanechol chloride)
✔✔Side effects of cholinergics - ✔✔BUDGES
B-bradycardia
U-urinary incontinence
D- diarrhea, diaphoresis
G- GI cramps
E- emesis
S- Salivation
✔✔What are cholinergics used to treat? - ✔✔glaucoma, myasthenia gravis, Alzheimers,
food poisoning, over doses.
✔✔Pharmacokinetcs - ✔✔what the body does to the drug
*absorption
*distribution
*biotransformation
*elimination
✔✔Mechanism of action - ✔✔drug binds to a cellular receptor (reversible action). Drug
binding is selective, so not all drugs bind to all receptors.
✔✔Agonist - ✔✔binds and produces a response
✔✔antagonist - ✔✔binds and blocks an activity or a response.
✔✔Movement of drugs through the cell - ✔✔Phospholipid bilayer is composed of lipids
and proteins. Allows most lipid soluble compounds to pass. The cell membrane has
protein molecules that act as carrier molecules to pass the drug through.
TEST PAPER 2026 QUESTIONS AND ANSWERS SURE
A+
✔✔atropine- indications - ✔✔*symptomatic bradycardia (sinus, junctional, AV blocks,
causing significant hypotension, ventricular ectopy, angina, etc.)
*organphosphate poisoning
* RSI in peds
*beta blocker and calcium channel blocker overdose
✔✔atropine- contraindications - ✔✔*tachycardia
*HTN
*hypothermic bradycardia
*narrow angle glaucoma
✔✔atropine adverse reactions - ✔✔drowsiness, confusion, HA, tachycardia,
palpitations, dysrhythmias, N/V, paradoxical bradycardia if pushed too slowly or given in
low doses
✔✔atropine special considerations to know - ✔✔Pregnancy category C
paradoxical bradycardia can occur with doses lower than 0.1 mg.
, ✔✔Types of cholinergic receptors - ✔✔1. Muscarinic (G protein linked)
-M2- health and smooth muscle
-M3- glands and endothelium
-M1,4,5-nerves
2. Nicotinic receptors (ion channel mediated)
- Nm-Skeletal muscle
-Nn- autonomic ganglion cells
**activated by acetlycholine
✔✔What neurotransmitter do cholinergics mimic? - ✔✔acetycholine
✔✔direct acting cholinergics - ✔✔pilocar (pilocarpine)
reglan (metoclopramide)
Urecholine (bethanechol chloride)
✔✔Side effects of cholinergics - ✔✔BUDGES
B-bradycardia
U-urinary incontinence
D- diarrhea, diaphoresis
G- GI cramps
E- emesis
S- Salivation
✔✔What are cholinergics used to treat? - ✔✔glaucoma, myasthenia gravis, Alzheimers,
food poisoning, over doses.
✔✔Pharmacokinetcs - ✔✔what the body does to the drug
*absorption
*distribution
*biotransformation
*elimination
✔✔Mechanism of action - ✔✔drug binds to a cellular receptor (reversible action). Drug
binding is selective, so not all drugs bind to all receptors.
✔✔Agonist - ✔✔binds and produces a response
✔✔antagonist - ✔✔binds and blocks an activity or a response.
✔✔Movement of drugs through the cell - ✔✔Phospholipid bilayer is composed of lipids
and proteins. Allows most lipid soluble compounds to pass. The cell membrane has
protein molecules that act as carrier molecules to pass the drug through.
