QUESTIONS AND ANSWERS SURE A+
✔✔For each medication class listed, indicate the drug-to-drug indication that can occur
when given with a nonsteroidal anti-inflammatory drug (NSAID). Note: Some medication
classes may be associated with more than one drug-to-drug interaction. -
✔✔*Prolonged Bleeding Time:*
Anticoagulants
Cephalosporins
Thrombolytic agents
Salicylates
*Increased Gastrointestinal Side Effects:*
Salicylates
*Decreased Medication Effectiveness:*
Salicylates
Diuretics
Antihypertensives
✔✔What is the primary indication for administering low-dose acetylsalicylic acid daily? -
✔✔Cardiovascular protection
, ✔✔Which three properties do all nonsteroidal anti-inflammatory drugs (NSAIDs) share?
Select that all apply. - ✔✔Analgesic
Anti-inflammatory
Antipyretic
✔✔__________ is commonly used to prevent myocardial infarctions and transient
ischemic attacks. - ✔✔Aspirin
✔✔To which class of medications do salicylates belong? - ✔✔Nonsteroidal anti-
inflammatory (NSAIDs)
✔✔Salicylates are used as which of the following? Select all that apply. - ✔✔Antiplatelet
Anti-inflammatory
Analgesic
Antipyretic
✔✔Aspirin is a(n) __________ inhibitor of cyclooxygenase 1 (COX-1) receptors within
the platelets themselves. It causes a(n) __________ in the formation of thromboxane
A2, a substance that normally __________ platelet aggregation. - ✔✔Irreversible
Reduction
Promotes
✔✔Aspirin is commonly used to prevent which conditions? Select all that apply. -
✔✔Myocardial infarction (MI)
Cerebral vascular accident (CVA or stroke)
Transient ischemic attacks (TIA)
✔✔By which routes can salicylates be administered? Select all that apply. - ✔✔Rectal
Oral
✔✔Clients with which conditions should use aspirin with caution? - ✔✔Bleeding
disorders
✔✔Reye's syndrome is a(n) __________ and potentially life-threatening condition that
can cause progressive and possibly permanent __________ damage. - ✔✔Acute
Neurologic
✔✔Which clinical manifestations are adverse effects of salicylates? Select all that apply.
- ✔✔Gastrointestinal (GI) bleeding
Hypoglycemia
Tinnitus
✔✔Which client should not receive aspirin? - ✔✔8-year-old with influenza