Nsg 2600 Sepsis Sirs Septic Shock Mods Dic Questions And Answers Adult Health Nursing Study Guide 2026/2027 | Complete Exam Review

NSG 2600 SEPSIS SIRS SEPTIC SHOCK MODS DIC QUESTIONS AND ANSWERS ADULT HEALTH
NURSING STUDY GUIDE 2026/2027 | COMPLETE EXAM REVIEW



Sepsis (definition): - ANS ✔✔● Life-threatening organ dysfunction caused by a dysregulated
host response to infection



Septic shock chain of progression: - ANS ✔✔● Local infection

[↓]

● Systemic infection (early sepsis)

[↓]

● SIRS (Systemic Inflammatory Response Syndrome)

[↓]

● Organ failure (severe sepsis)

[↓]

● Multiple Organ System Failure (MODS ~ septic shock)



Pathophys of sepsis: - ANS ✔✔● Widespread infection w/ general systemic inflammatory
response to documented / suspected infection

● Infection escapes local control, enters bloodstream (bacteremia)



Bacteria most associated w/ sepsis: - ANS ✔✔● Gram [-]

- Staph

- E. coli



● Gram [+]

- Strep

, Risk / rationale for danger posed by gram [-] bacteria: - ANS ✔✔● Endotoxins released as gram
[-] bacteria are lysed

● Endotoxins can lead to widespread inflammation / septic reactions / DIC (at large enough
concentrations)



Two antibiotics most associated w/ gram [-] bacteria: - ANS ✔✔● Vancomycin

● Gentamicin



(Pharm reminder: Both drugs come w/ risk to pt of ototoxicity & nephrotoxicity...)



Urosepsis: - ANS ✔✔● Sepsis caused by UTI (most generally E. coli...)



Predisposing factors for sepsis: - ANS ✔✔● Infection w/ resistant microorganisms

● Immunosuppression

● Cancer

● > 80 yr old

● Chemotherapy

● Alcoholism

● DM

● Chronic kidney disease

● Hepatitis

--- (added in class) ---

● Invasive instrumentation (central lines; catheters; etc.,)

● Surgeries



SIRS (Systemic Inflammatory Response Syndrome): - ANS ✔✔● Release of infection / toxins
(sepsis) resulting in widespread inflammation