BSNC 6000 Final – Pharmacology Questions
with 100% Correct Answers
Amiodarone
Class: antiarrhythmic (class III)
MOA: potassium-channel blocker; prolongs refractory period and dec AV conduction and
sinus function. Also has alpha and beta blocking properties
Other:
HIGH RISK; only use for life-threatening arrythmias (supraventricular, ventricular); toxicity
risk
Apixaban
Class: Factor Xa inhibitor (anticoagulant; DOAC)
MOA: inhibits platelet activation and fibrin clot formation -> dec risk for clots
Other:
risk for bleeding, esp when used in combo with other anticoagulants, aspirin, fibrinolytics,
NSAIDs, SSRIs and SNRIs
Clindamycin
Class: anti-infective
MOA: inhibits protein synthesis in susceptible bacteria (gram-positive)
, Emtricitabine/Tenofovir
Class: Antiretroviral; nucleoside reverse transcriptase inhibitors
MOA: Prevents viral replication
Side Effects: Jaundice, lactic acidosis
Monitor LFTs and report jaundice
Gabapentin
Class: antiseizure agent, GABA analogue, analgesic adjunct, mood stabilizer
MOA: acts on neurotransmitters (can pass BBB); inhibits release of excitatory NTs
Other: do not abruptly stop anti-seizure meds. May inc risk for SI. Do not take within 2h of
antacid
Hydroxychloroquine
Class: anti-malarial, antirheumatic
MOA: (lupus) calms overactive immune system (slows locomotion of neutrophils etc.)
Other: retinopathy risk - need periodic ocular exams
Lactulose
with 100% Correct Answers
Amiodarone
Class: antiarrhythmic (class III)
MOA: potassium-channel blocker; prolongs refractory period and dec AV conduction and
sinus function. Also has alpha and beta blocking properties
Other:
HIGH RISK; only use for life-threatening arrythmias (supraventricular, ventricular); toxicity
risk
Apixaban
Class: Factor Xa inhibitor (anticoagulant; DOAC)
MOA: inhibits platelet activation and fibrin clot formation -> dec risk for clots
Other:
risk for bleeding, esp when used in combo with other anticoagulants, aspirin, fibrinolytics,
NSAIDs, SSRIs and SNRIs
Clindamycin
Class: anti-infective
MOA: inhibits protein synthesis in susceptible bacteria (gram-positive)
, Emtricitabine/Tenofovir
Class: Antiretroviral; nucleoside reverse transcriptase inhibitors
MOA: Prevents viral replication
Side Effects: Jaundice, lactic acidosis
Monitor LFTs and report jaundice
Gabapentin
Class: antiseizure agent, GABA analogue, analgesic adjunct, mood stabilizer
MOA: acts on neurotransmitters (can pass BBB); inhibits release of excitatory NTs
Other: do not abruptly stop anti-seizure meds. May inc risk for SI. Do not take within 2h of
antacid
Hydroxychloroquine
Class: anti-malarial, antirheumatic
MOA: (lupus) calms overactive immune system (slows locomotion of neutrophils etc.)
Other: retinopathy risk - need periodic ocular exams
Lactulose
