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NR 283 – Pathophysiology Exam 1 Comprehensive Review Study Guide with Practice Questions Latest Edition (2026)

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This document provides a comprehensive study guide for NR 283 Pathophysiology Exam 1 preparation, updated for 2026. It includes extensive review materials and practice questions covering foundational pathophysiology concepts such as cellular adaptations, genetic and developmental disorders, inflammation, immune responses, fluid and electrolyte imbalances, acid-base disturbances, and basic mechanisms underlying disease processes. The material is designed to support structured revision, reinforce essential pathophysiological principles, and improve preparedness for examinations and clinical nursing application. References to “verified answers,” “most tested concepts,” or grades such as “A+” should be regarded as study claims and not as official examination materials or guarantees of future performance.

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NR283 PATHO EXAM 1 COMPREHENSIVE
QUESTIONS WITH VERIFIED AND CORRECT
ANSWERS, FREQUENTLY MOST TESTED GRADED
A+ LATEST 2026 EDITION

1. Which of the following would be the most likely cause of an iatrogenic disease?
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a. An inherited disorder
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b. A combination of specific etiological factors
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c. An unwanted effect of a prescribed drug
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d. Prolonged exposure to toxic chemicals in the environment - ans-
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c. An unwanted effect of a prescribed drug
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2. The manifestations of a disease are best defined as the:
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a. subjective feelings of discomfort during a chronic illness.
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b. signs and symptoms of a disease.
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c. factors that precipitate an acute episode of a chronic illness.
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d. early indicators of the prodromal stage of infection. - ans-
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b. signs and symptoms of a disease
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3. The best definition of the term prognosis is the:
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a. precipitating factors causing an acute episode.
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b. number of remissions to be expected during the course of a chronic illness.
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,c. predicted outcome or likelihood of recovery from a specific disease.
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d. exacerbations occurring during chronic illness. - ans-
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c. predicted outcome or likelihood of recovery from a specific disease.
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4. Which of the following is considered a systemic sign of disease?
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a. Swelling of the knee
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b. Fever
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c. Pain in the neck
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d. Red rash on the face - ans-b. Fever
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5. Etiology is defined as the study of the:
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a. causes of a disease.
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b. course of a disease.
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c. expected complications of a disease.
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d. manifestations of a disease. - ans-a. causes of a disease.
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6. A type of cellular adaptation in which there is a decrease in cell size is referred t
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o as:ws




a. hypertrophy.
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b. metaplasia.
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c. anaplasia.
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d. atrophy. - ans-d. atrophy.
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7. A change in a tissue marked by cells that vary in size and shape and show incre
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ased mitotic figures would be called:
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a. metaplasia.
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b. atrophy.
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c. dysplasia.
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d. hypertrophy. - ans-c. dysplasia.
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,8. A deficit of oxygen in the cells usually due to respiratory or circulatory problems i
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s called:
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a. apoptosis.
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b. ischemia.
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c. hypertrophy.
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d. necrosis. - ans-b. ischemia
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9. When a group of cells in the body dies, the change is called:
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a. ischemia.
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b. gangrene.
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c. hypoxia.
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d. necrosis. - ans-d. necrosis
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10. Rigorous weight lifting/
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body building regimens may result in the skeletal muscle cells undergoing:
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a. hypertrophy.
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b. dysplasia.
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c. atrophy.
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d. regeneration. - ans-a. hypertrophy
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11. The term cancer refers to:
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a. dysplasia.
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b. hyperplasia.
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c. metaplasia.
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d. malignant neoplasm. - ans-d. malignant neoplasm.
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12. To which of the following does the term apoptosis refer?
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a. Increased rate of mitosis by certain cells
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, b. Ischemic damage to cells
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c. Liquefaction of necrotic tissue
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d. Preprogrammed cell self-destruction - ans-d. Preprogrammed cell self-destruction
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13. Which of the following statements is TRUE?
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a. Alteration of DNA does not change cell function.
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b. Damaged cells may be able to repair themselves.
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c. All types of cells die at the same rate.
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d. Mild ischemia causes immediate cell death. - ans-
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b. Damaged cells may be able to repair themselves.
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14. Caseation necrosis refers to an area where:
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a. cell proteins have been denatured.
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b. cell are liquefied by enzymes.
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c. dead cells form a thick cheesy substance.
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d. bacterial invasion has occurred. - ans-c. dead cells form a thick cheesy substance
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15. Routine application of sun block to skin would be an example of:
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a. an iatrogenic cause of cancer.
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b. a preventive measure.
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c. a precipitating factor.
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d. a predisposing condition. - ans-b. a preventive measure.
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16. A circumstance that causes a sudden acute episode of a chronic disease to occ
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ur is termed:
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a. latent stage.
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b. predisposing factor.
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c. incidence.
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