Missouri Physician Licensing Exam
Practice Questions And Correct Answers
(Verified Answers) Plus Rationales 2026
Q&A | Instant Download Pdf
1. A 65-year-old man presents with chest pain radiating to the left arm.
ECG shows ST elevation in leads II, III, aVF. What is the most likely
diagnosis?
A. Anterior MI
B. Inferior MI
C. Pericarditis
D. Pulmonary embolism
Answer: B
Rationale: ST elevation in II, III, aVF indicates inferior wall myocardial
infarction.
2. First-line treatment for anaphylaxis is:
A. Diphenhydramine
B. Epinephrine
C. Corticosteroids
, D. Albuterol
Answer: B
Rationale: Epinephrine is the immediate life-saving treatment for
anaphylaxis.
3. Most common cause of community-acquired pneumonia:
A. Klebsiella pneumoniae
B. Streptococcus pneumoniae
C. Pseudomonas aeruginosa
D. Mycoplasma hominis
Answer: B
Rationale: Streptococcus pneumoniae is the most common cause.
4. A patient with diabetes has fruity breath odor. Likely diagnosis?
A. Hypoglycemia
B. Diabetic ketoacidosis
C. Hyperosmolar state
D. Renal failure
Answer: B
Rationale: Acetone breath is characteristic of DKA.
5. Most sensitive test for pulmonary embolism:
A. Chest X-ray
B. D-dimer
C. CT pulmonary angiography
D. ECG
, Answer: C
Rationale: CTPA is the gold standard imaging test.
6. Drug of choice for tuberculosis:
A. Amoxicillin
B. Isoniazid, rifampin, pyrazinamide, ethambutol
C. Ceftriaxone
D. Azithromycin
Answer: B
Rationale: Standard RIPE therapy is first-line for TB.
7. Vitamin deficiency causing night blindness:
A. Vitamin C
B. Vitamin A
C. Vitamin D
D. Vitamin K
Answer: B
Rationale: Vitamin A deficiency leads to night blindness.
8. Most common cause of peptic ulcer disease:
A. NSAIDs
B. H. pylori
C. Alcohol
D. Stress
Answer: B
Rationale: H. pylori infection is the leading cause.
, 9. Insulin is produced by:
A. Alpha cells
B. Beta cells
C. Delta cells
D. Acinar cells
Answer: B
Rationale: Pancreatic beta cells secrete insulin.
10. Normal adult respiratory rate:
A. 8–10
B. 12–20
C. 20–30
D. 30–40
Answer: B
Rationale: Normal RR is 12–20 breaths/min.
11. Most common site of metastasis for prostate cancer:
A. Brain
B. Liver
C. Bone
D. Lung
Answer: C
Rationale: Prostate cancer commonly spreads to bone.
12. First-line treatment for hypertension (uncomplicated):
A. ACE inhibitors
Practice Questions And Correct Answers
(Verified Answers) Plus Rationales 2026
Q&A | Instant Download Pdf
1. A 65-year-old man presents with chest pain radiating to the left arm.
ECG shows ST elevation in leads II, III, aVF. What is the most likely
diagnosis?
A. Anterior MI
B. Inferior MI
C. Pericarditis
D. Pulmonary embolism
Answer: B
Rationale: ST elevation in II, III, aVF indicates inferior wall myocardial
infarction.
2. First-line treatment for anaphylaxis is:
A. Diphenhydramine
B. Epinephrine
C. Corticosteroids
, D. Albuterol
Answer: B
Rationale: Epinephrine is the immediate life-saving treatment for
anaphylaxis.
3. Most common cause of community-acquired pneumonia:
A. Klebsiella pneumoniae
B. Streptococcus pneumoniae
C. Pseudomonas aeruginosa
D. Mycoplasma hominis
Answer: B
Rationale: Streptococcus pneumoniae is the most common cause.
4. A patient with diabetes has fruity breath odor. Likely diagnosis?
A. Hypoglycemia
B. Diabetic ketoacidosis
C. Hyperosmolar state
D. Renal failure
Answer: B
Rationale: Acetone breath is characteristic of DKA.
5. Most sensitive test for pulmonary embolism:
A. Chest X-ray
B. D-dimer
C. CT pulmonary angiography
D. ECG
, Answer: C
Rationale: CTPA is the gold standard imaging test.
6. Drug of choice for tuberculosis:
A. Amoxicillin
B. Isoniazid, rifampin, pyrazinamide, ethambutol
C. Ceftriaxone
D. Azithromycin
Answer: B
Rationale: Standard RIPE therapy is first-line for TB.
7. Vitamin deficiency causing night blindness:
A. Vitamin C
B. Vitamin A
C. Vitamin D
D. Vitamin K
Answer: B
Rationale: Vitamin A deficiency leads to night blindness.
8. Most common cause of peptic ulcer disease:
A. NSAIDs
B. H. pylori
C. Alcohol
D. Stress
Answer: B
Rationale: H. pylori infection is the leading cause.
, 9. Insulin is produced by:
A. Alpha cells
B. Beta cells
C. Delta cells
D. Acinar cells
Answer: B
Rationale: Pancreatic beta cells secrete insulin.
10. Normal adult respiratory rate:
A. 8–10
B. 12–20
C. 20–30
D. 30–40
Answer: B
Rationale: Normal RR is 12–20 breaths/min.
11. Most common site of metastasis for prostate cancer:
A. Brain
B. Liver
C. Bone
D. Lung
Answer: C
Rationale: Prostate cancer commonly spreads to bone.
12. First-line treatment for hypertension (uncomplicated):
A. ACE inhibitors
