BMTCN QUESTIONS AND ANSWERS SURE A+
✔✔Treatment with long-term corticosteroids increases the risk of which of the following
complications? - ✔✔Long-term use of corticosteroids such as in the treatment of GVHD
is known to increase the risk of developing avascular necrosis thru ischemic (non-
traumatic) bone necrosis
✔✔A patient reports weakness, fatigue, and a decreased desire to socialize with family
and friends after transplant. What should the nurse do? - ✔✔Studies have shown that
regular aerobic exercise can help to decrease fatigue and improve overall well-being.
✔✔Which of the following is a chemokine receptor that helps to regulate stem cell
release into the peripheral circulation? - ✔✔CXCR4 has been identified as being
important in the regulation of trafficking and homing of cells involved in hematopoiesis
and the immune system.
✔✔Which of the following is an advantage of using bone marrow as a source of stem
cells? - ✔✔Obtaining cells from the bone marrow is a much faster process than
obtaining them from the peripheral blood.
✔✔Tissue damage within target organs due to activated T-cells occurs in which phase
of GVHD? - ✔✔During phase 3, activated T lymphocytes either directly or indirectly
produce or amplify tissue damage within the target organs.
✔✔What is the most likely cause for the development of cataracts following an HSCT? -
✔✔Steroid use contributes to the development of cataracts
✔✔A patient who is day +35 allogeneic HSCT develops a pruritic, erythematous,
maculopapular rash on the plantar and palmar surfaces. What does this indicate? -
✔✔A pruritic or painful erythematous maculopapular rash on the plantar and palmar
surfaces in a patient 2-5 weeks following an allogeneic HSCT is likely acute GVHD.
, ✔✔Patients who have received an HSCT should receive which of the following annual
immunizations? - ✔✔Inactivated influenza is recommended yearly
✔✔Which is an important predictive marker of T cell immune recovery following HSCT?
- ✔✔CD4+ counts are one of the most predictive markers of immune recovery after
HSCT.
✔✔What is the treatment for a patient after an allogeneic transplant who is diagnosed
with thrombotic microangiopathy? - ✔✔Calcineurin inhibitors will be discontinued for
patients who are diagnosed with thrombotic microangiopathy
✔✔Which of the following clinical findings is associated with polymyositis? -
✔✔Proximal muscle weakness is associated with polymyositis
✔✔A conditioning regimen that includes cyclophosphamide may cause which side
effect during the initial two weeks post-transplant? - ✔✔Conditioning regimens that
include cyclophosphamide increase the risk of pleural effusion in the immediate post-
transplant period.
✔✔Which of the following is a disadvantage of a syngeneic transplant? - ✔✔A
syngeneic transplant lacks the graft-versus-tumor effect which is beneficial for the
patient.
✔✔A conditioning regimen that contains which of the following medications would most
likely cause heart failure? - ✔✔Regimens containing cyclophosphamide can cause
cardiomyopathy and HF in particular.
✔✔Skin GVHD stage 1 - ✔✔maculopapular eruption over <25% of the body area
✔✔Skin GVHD stage 2 - ✔✔maculopapular eruption over25%-50% of the body area
✔✔Skin GVHD stage 3 - ✔✔Generalized erythroderma
✔✔Skin GVHD stage 4 - ✔✔Generalized erythroderma with bullous formation and often
desquamation
✔✔Liver GVHD stage 1 - ✔✔bilirubin 2-3
✔✔Liver GVHD stage 2 - ✔✔bilirubin 3.1-6
✔✔Liver GVHD stage 3 - ✔✔bilirubin 6.1-15
✔✔Liver GVHD stage 4 - ✔✔bilirubin >15
✔✔Treatment with long-term corticosteroids increases the risk of which of the following
complications? - ✔✔Long-term use of corticosteroids such as in the treatment of GVHD
is known to increase the risk of developing avascular necrosis thru ischemic (non-
traumatic) bone necrosis
✔✔A patient reports weakness, fatigue, and a decreased desire to socialize with family
and friends after transplant. What should the nurse do? - ✔✔Studies have shown that
regular aerobic exercise can help to decrease fatigue and improve overall well-being.
✔✔Which of the following is a chemokine receptor that helps to regulate stem cell
release into the peripheral circulation? - ✔✔CXCR4 has been identified as being
important in the regulation of trafficking and homing of cells involved in hematopoiesis
and the immune system.
✔✔Which of the following is an advantage of using bone marrow as a source of stem
cells? - ✔✔Obtaining cells from the bone marrow is a much faster process than
obtaining them from the peripheral blood.
✔✔Tissue damage within target organs due to activated T-cells occurs in which phase
of GVHD? - ✔✔During phase 3, activated T lymphocytes either directly or indirectly
produce or amplify tissue damage within the target organs.
✔✔What is the most likely cause for the development of cataracts following an HSCT? -
✔✔Steroid use contributes to the development of cataracts
✔✔A patient who is day +35 allogeneic HSCT develops a pruritic, erythematous,
maculopapular rash on the plantar and palmar surfaces. What does this indicate? -
✔✔A pruritic or painful erythematous maculopapular rash on the plantar and palmar
surfaces in a patient 2-5 weeks following an allogeneic HSCT is likely acute GVHD.
, ✔✔Patients who have received an HSCT should receive which of the following annual
immunizations? - ✔✔Inactivated influenza is recommended yearly
✔✔Which is an important predictive marker of T cell immune recovery following HSCT?
- ✔✔CD4+ counts are one of the most predictive markers of immune recovery after
HSCT.
✔✔What is the treatment for a patient after an allogeneic transplant who is diagnosed
with thrombotic microangiopathy? - ✔✔Calcineurin inhibitors will be discontinued for
patients who are diagnosed with thrombotic microangiopathy
✔✔Which of the following clinical findings is associated with polymyositis? -
✔✔Proximal muscle weakness is associated with polymyositis
✔✔A conditioning regimen that includes cyclophosphamide may cause which side
effect during the initial two weeks post-transplant? - ✔✔Conditioning regimens that
include cyclophosphamide increase the risk of pleural effusion in the immediate post-
transplant period.
✔✔Which of the following is a disadvantage of a syngeneic transplant? - ✔✔A
syngeneic transplant lacks the graft-versus-tumor effect which is beneficial for the
patient.
✔✔A conditioning regimen that contains which of the following medications would most
likely cause heart failure? - ✔✔Regimens containing cyclophosphamide can cause
cardiomyopathy and HF in particular.
✔✔Skin GVHD stage 1 - ✔✔maculopapular eruption over <25% of the body area
✔✔Skin GVHD stage 2 - ✔✔maculopapular eruption over25%-50% of the body area
✔✔Skin GVHD stage 3 - ✔✔Generalized erythroderma
✔✔Skin GVHD stage 4 - ✔✔Generalized erythroderma with bullous formation and often
desquamation
✔✔Liver GVHD stage 1 - ✔✔bilirubin 2-3
✔✔Liver GVHD stage 2 - ✔✔bilirubin 3.1-6
✔✔Liver GVHD stage 3 - ✔✔bilirubin 6.1-15
✔✔Liver GVHD stage 4 - ✔✔bilirubin >15
