Foundations of Pharmacology
Drug Development,
Pharmacokinetics, and Autonomic
System
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,Why is pharmacology important in It is essential for patient safety, drug
advanced nursing practice? administration, and prescribing effective and safe
drugs.
What are the three most important Effectiveness, safety, and selectivity.
properties of a drug?
What is the purpose of Phase I To establish drug safety and dosage with healthy
clinical drug development? volunteers.
What is the focus of Phase II clinical To establish drug side effects and efficacy in
drug development? individuals with the disease.
What is the goal of Phase III clinical To demonstrate drug efficacy and side effects in
drug development? a larger cohort.
What is a randomized controlled A study design that uses controls, randomization,
trial? and blinding to test drug efficacy.
, What are the limitations of drug Challenges include population diversity,
development? detecting adverse effects, and short study times.
What is Phase IV clinical drug Post-market surveillance to monitor drug effects
development? in the general population.
What are immunomodulators? Drugs that modify the immune response, often
ending in 'mab' (monoclonal antibodies).
What does 'mu' indicate in It indicates that the antibody is derived from a
monoclonal antibodies? mouse.
What is pharmacokinetics? The study of what the body does to the drug,
including its movement through the body.