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Michael L. Bishop Clinical Chemistry 9th Edition Study Guide | Laboratory Science Review, Questions & Exam Preparation 2026/2027

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Prepare for Clinical Chemistry exams with this comprehensive study resource based on Michael L. Bishop’s Clinical Chemistry Principles, Techniques, and Correlations 9th Edition. Includes key concepts, laboratory techniques, clinical correlations, practice questions, and verified answers for MLS and healthcare students.

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Full Exam Prep for:

Clinical Chemistry
Principles, Techniques and
Correlations with Navigate Advantages
Access 9th Edition By Michael L
Bishop




** Expert-Verified Explanation
** Questions with Verified Answer
** New Edition | 2026-2027 Updated
** 100% Guaranteed Pass
** 100% Correct Answers | Graded A+

,What is the molarity for a solution containing 100 g of a. 3.45 M
NaCl made up to 500 mL with distilled water? Assume a
gram molecular weight (from periodic table) of
approximately 58 grams.
a. 3.45 M
b. 1.72 M
c. 290 M
d. 5.27 M


What is the normality for a solution containing 100 g of a. 3.45
NaCl made up to 500 mL with distilled water? Assume a
gram molecular weight (from periodic table) of
approximately 58 grams.
a. 3.45
b. 0.86
c. 1.72
d. 6.9


What is the percent (w/v) for a solution containing 100 g a. 20%
of NaCl made up to 500 mL with distilled water?
a. 20%
b. 5%
c. 29%
d. 58%


What is the dilution factor for a solution containing 100 g a. 1:5 or 1/5
of NaCl made up to 500 mL with distilled water?
a. 1:5 or 1/5
b. 5
c. 50 or 1/50
d. 10


What is the value in mg/dL for a solution containing 10 a. 10
mg of CaCl2 made with 100 mL of distilled water?
a. 10
b. 100
c. 50
d. Cannot determine without additional information


What is the molarity of a solution containing 10 a. 9 x 10-4
mg of CaCl2 made with 100 mL of distilled water?
Assume a gram molecular weight from the periodic table
of approximately 111 grams.
a. 9 × 10-4
b. 1.1 × 10-3
c. 11.1
d. 90


You must make 1L of 0.2M acetic acid(CH3COOH). All a. 11.7
you have available is concentrated glacial acetic acid
(assay value, 98%; specific gravity, 1.05 g/mL). It will
take ______ milliliters of acetic acid to make this
solution. Assume a gram molecular weight of 60.05
grams.
a. 11.7
b. 1.029
c. 3.42
d. 12.01


What is the hydrogen ion concentration of an acetate a. 5.75 x 10-5
buffer having a pH of 4.24?
a. 5.75 × 10-5
b. 1.19 × 10-1
c. 0.62
d. 0.76 × 10-4


Using the Henderson-Hasselbalch equation, give the a. 14.7/1
ratio of salt to weak acid for a Veronal buffer
withapHof8.6andapKa of 7.43.
a. 14.7/1
b. 1/8.6
c. 1.17/1
d. 1/4.3

,The pKa for acetic acid is 4.76. If the concentra- tion of a. 4.46
salt is 5 mmol/L and that of acetic acid is 10 mmol/L,
what is the expected pH?
a. 4.46
b. 5.06
c. 104
d. 56


The hydrogen ion concentration of a solution is a. 4.03.
0.0000937. What is the pH?
a. 4.03
b. 9.37 × 10-5
c. 9.07
d. 8.03


Perform the following conversions: 4×104 mg= 40 g
4×104 mg=___g 1.3×102 mL= 1.3 dL
1.3×102 mL=____dL 0.02 mL = 20 μL
0.02 mL = ____ μL 5×10-3 mL= 5 μL
5×10-3 mL=___μL 5×10-2 L= 50 mL
5×10-2 L=___mL 4 cm = 40 mm
4 cm = _____ mm


What volume of 14 N H2SO4 is needed to make a. 114 mL
250 mL of 3.2 M H2SO4 solution? Assume a gram
molecular weight of 98.08 grams.
a. 114 mL
b. 1.82 mL
c. 1.75 mL
d. 7 mL


A 1:200 dilution of the urine specimen gives a creatinine a. 160
result of 0.8 mg/dL. The serum value is 1.2 mg/dL. What
is the final value of creatinine in mg/dL in the undiluted
urine sample?
a. 160
b. 0.8
c. 960
d. 860


A 24-hour urine has a total volume of 1,200 mL. A 1:200 a. 1.92
dilution of the urine specimen gives a creatinine result of
0.8 mg/dL. The serum value is 1.2 mg/dL. What is the
result in terms of grams per 24 hours?
a. 1.92
b. 0.08
c. 80
d. 19


A new medical technologist was selecting analyte e. ACS with impurities listed
standards to develop a standard curve for a high-
performance liquid chromatography (HPLC) procedure.
This analyte must have a 100% purity level and must be
suitable for HPLC. Which of the following labels would be
most appropriate for this procedure?
a. ACS with no impurities listed
b. USP
c. NF
d. CP
e. ACS with impurities listed


When selecting quality control reagents for measuring an a. A quality control reagent prepared in a urine matrix
analyte in urine, the medical technologist should select:
a. A quality control reagent prepared in a urine matrix.
b. A quality control reagent prepared in a serum matrix.
c. A quality control reagent prepared in deionized water.
d. The matrix does not matter; any quality control
reagent as long as the analyte of measure is chemically
pure.

, A patient's serum sample was placed on the chemistry e. Type I water
analyzer and the output indicated "out of range" for the
measurement of creatine kinase (CK) enzyme. A dilution
of the patient serum was required. Which of the following
should be used to prepare a dilution of patient serum?
a. Deionized water
b. Tap water
c. Another patient's serum with confirmed, low
levels of CK
d. Type III water
e. Type I water


True or False? Laboratory liquid in glass thermometers True
should be calibrated against an NIST-certified
thermometer.


Which of the following containers is calibrated to hold a. Volumetric flask
only one exact volume of liquid?
a. Volumetric flask
b. Erlenmeyer flask
c. Griffin beaker
d. Graduated cylinder


Which of the following does NOT require calibration in d. Volumetric flask
the clinical laboratory?
a. Electronic balance
b. Liquid in glass thermometer
c. Centrifuge
d. Volumetric flask
e. Air displacement pipet


Which of the following errors is NOT considered a d. The serum sample was diluted with tap water.
preanalytical error?
a. During a phlebotomy procedure, the patient is opening
and clenching his fist multiple times.
b. The blood was not permitted to clot and spun in a
centrifuge after 6 minutes of collection.
c. The patient was improperly identified leading to a
mislabeled blood sample.
d. The serum sample was diluted with tap water.
e. During phlebotomy, the EDTA tube was collected prior
to the red clot tube.


Which of the following standards requires that SDSs are a. Hazard Communication Standard
accessible to all employees who come in contact with a
hazardous compound?
a. Hazard Communication Standard
b. Bloodborne Pathogen Standard
c. CDC Regulations
d. Personal Protection Equipment Standard


Chemicals should be stored a. According to their chemical properties and classification
a. According to their chemical properties and
classification
b. Alphabetically, for easy accessibility
c. Inside a safety cabinet with proper ventilation
d. Inside a fume hood, if toxic vapors can be
released when opened


Proper PPE in the chemistry laboratory for routine testing a. Impermeable lab coat with eye/face protection and appropriate disposable
includes gloves
a. Impermeable lab coat with eye/face protection and
appropriate disposable gloves
b. Respirators with HEPA filter
c. Gloves with rubberized sleeves
d. Safety glasses for individuals not wearing contact
lenses


A fire caused by a flammable liquid should be a. Class B
extinguished using which type of extinguisher?
a. Class B
b. Halogen
c. Pressurized water d. Class C

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