Types of Exoenzymes
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glycohydrolases, nucleases, phospholipases, and proteases; Ex.
Hyaluronidase
Focal infection
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pathogen or toxin spreads to secondary location
Non-communicable
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obtained from non-living thing such as soil or contaminated object
Exotoxins: Superantigen
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trigger excessive production of cytokines by immune cells; Ex.
Staphylococcus aureus and Toxic Shock Syndrome
Communicable
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capable of spreading person-to-person
Median Lethal Dose (LD50)
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number of pathogens required to kill 50% of pop.
Systemic infection
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, occurs throughout body; commonly by blood stream
What can influence susceptibility to disease?
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Drugs, resident microbiota, genetics, and age
Toxins
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poisons that cause host cell toxigenicity
Acute disease
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relatively short (hours, days, weeks); ex. influenza
Endotoxins
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glycohydrolases, nucleases, phospholipases, and proteases; Ex.
Hyaluronidase
Focal infection
Give this one a try later!
pathogen or toxin spreads to secondary location
Non-communicable
,Give this one a try later!
obtained from non-living thing such as soil or contaminated object
Exotoxins: Superantigen
Give this one a try later!
trigger excessive production of cytokines by immune cells; Ex.
Staphylococcus aureus and Toxic Shock Syndrome
Communicable
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capable of spreading person-to-person
Median Lethal Dose (LD50)
Give this one a try later!
number of pathogens required to kill 50% of pop.
Systemic infection
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, occurs throughout body; commonly by blood stream
What can influence susceptibility to disease?
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Drugs, resident microbiota, genetics, and age
Toxins
Give this one a try later!
poisons that cause host cell toxigenicity
Acute disease
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relatively short (hours, days, weeks); ex. influenza
Endotoxins
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