NUR 751 Basics of Pharm–Questions and Answers |
2026 Update | 100% Correct.
agonist ; antagonist ; partial ; inverse
Receptors:
-_______ = drugs that occupy receptor & activate them
-__________ = drugs that occupy receptor but do NOT activate = block receptor activation
-_______ agonist = occupy receptor but does not cause 100% effect
-_______ agonist = binds to a receptor & causes the opposite effect
inhibits ; reversible ; after ; overcome ; covalent ; allosteric
Receptors:
-Competitive antagonism = increasing concentration of antagonist _________ response to
agonist (____________) (shifts dose response curve right)
-Noncompetitive antagonism = even _____ admin of antagonist, high concentrations
of agonist can NOT completely _______ antagonism = either antagonist irreversibly
bound (________) or __________ interaction w/ receptor (change in shape) (shifts dose
response curve down)
addition ; 1+1=2 ; synergism ; 1+1=3 ; potentiation ; 1+0=3 ; antagonism ; 1+1=0
Co-Administration:
-________ = effect of 2 drugs is additive (_+_=_)
-_________ = effect of 2 drugs is greater than sum of their individual effects (_+_=_)
, -__________ = effect of a drug is enhanced by a drug that does NOT have an effect (_+_=_)
-_________ = effect of drug is counteracted (_+_=_)
increase ; decreased ; decrease ; increased
Receptor Action:
-Upregulation = _________ in # of receptors in response to _________ stimulation
-Downregulation = _________ in # of receptors in response to __________ stimulation
-Can be due to injury, disease, or meds
diffusion ; lipophilic ; hydrophilic ; CNS ; passive
-_______ = moving down a concentration gradient (high-to-low)
-Small ________ drugs can passively diffuse across the membrane freely
-_________ drugs need transmembrane proteins that form a hydrophilic
channel (to passively diffuse)
-There are non-specific hydrophilic channels in the capillary endothelium of all
organs EXCEPT for the ___ = NO _______ transport in the CNS
actively ; facilitated ; active ; elimination ; carrier
-No passive transport of hydrophilic drugs in CNS -> can only enter CNS binding to
transmembrane proteins that ________ transport them
-__________ diffusion = carrier proteins do NOT require energy + can NOT move against
gradient
2026 Update | 100% Correct.
agonist ; antagonist ; partial ; inverse
Receptors:
-_______ = drugs that occupy receptor & activate them
-__________ = drugs that occupy receptor but do NOT activate = block receptor activation
-_______ agonist = occupy receptor but does not cause 100% effect
-_______ agonist = binds to a receptor & causes the opposite effect
inhibits ; reversible ; after ; overcome ; covalent ; allosteric
Receptors:
-Competitive antagonism = increasing concentration of antagonist _________ response to
agonist (____________) (shifts dose response curve right)
-Noncompetitive antagonism = even _____ admin of antagonist, high concentrations
of agonist can NOT completely _______ antagonism = either antagonist irreversibly
bound (________) or __________ interaction w/ receptor (change in shape) (shifts dose
response curve down)
addition ; 1+1=2 ; synergism ; 1+1=3 ; potentiation ; 1+0=3 ; antagonism ; 1+1=0
Co-Administration:
-________ = effect of 2 drugs is additive (_+_=_)
-_________ = effect of 2 drugs is greater than sum of their individual effects (_+_=_)
, -__________ = effect of a drug is enhanced by a drug that does NOT have an effect (_+_=_)
-_________ = effect of drug is counteracted (_+_=_)
increase ; decreased ; decrease ; increased
Receptor Action:
-Upregulation = _________ in # of receptors in response to _________ stimulation
-Downregulation = _________ in # of receptors in response to __________ stimulation
-Can be due to injury, disease, or meds
diffusion ; lipophilic ; hydrophilic ; CNS ; passive
-_______ = moving down a concentration gradient (high-to-low)
-Small ________ drugs can passively diffuse across the membrane freely
-_________ drugs need transmembrane proteins that form a hydrophilic
channel (to passively diffuse)
-There are non-specific hydrophilic channels in the capillary endothelium of all
organs EXCEPT for the ___ = NO _______ transport in the CNS
actively ; facilitated ; active ; elimination ; carrier
-No passive transport of hydrophilic drugs in CNS -> can only enter CNS binding to
transmembrane proteins that ________ transport them
-__________ diffusion = carrier proteins do NOT require energy + can NOT move against
gradient
