S S S S S S
15th Edition by Bertram G. Katzung, Verified
S S S S S S S S
Chapters 1 – 66 S S S
,Table of Contents
S S
1. Introduction:STheSNatureSofSDrugsS&SDrugSDevelopmentS&SRegulation
2. DrugSReceptorsS&SPharmacodynamics
3. PharmacokineticsS&SPharmacodynamics:SRationalSDosingS&StheSTimeSCourseSofSDrugSAction
4. DrugSBiotransformation
5. Pharmacogenomics
6. IntroductionStoSAutonomicS Pharmacology
7. Cholinoceptor-ActivatingS&S Cholinesterase-InhibitingS Drugs
8. Cholinoceptor-BlockingS Drugs
9. AdrenoceptorS AgonistsS&SSympathomimeticS Drugs
10. AdrenoceptorSAntagonistSDrugs
11. AntihypertensiveS Agents
12. VasodilatorsS&StheSTreatmentSofSAnginaSPectoris
13. DrugsSUsedSinSHeartSFailure
14. AgentsSUsedSinSCardiacSArrhythmias
15. DiureticSAgents
16. Histamine,SSerotonin,S&StheSErgotSAlkaloids
17. VasoactiveS Peptides
18. TheSEicosanoids:S Prostaglandins,SThromboxanes,SLeukotrienes,S&SRelatedSCompounds
19. NitricSOxide
20. DrugsSUsedSinSAsthma
21. IntroductionStoStheSPharmacologySofSCNSSDrugs
22. Sedative-HypnoticS Drugs
23. TheSAlcohols
24. AntiseizureS Drugs
25. GeneralSAnesthetics
26. LocalSAnesthetics
27. SkeletalSMuscleSRelaxants
28. PharmacologicSManagementSofSParkinsonismS&SOtherSMovementSDisorders
29. AntipsychoticSAgentsS&SLithium
30. AntidepressantS Agents
31. OpioidSAgonistsS&SAntagonists
32. DrugsSofSAbuse
33. AgentsSUsedSinSCytopenias;SHematopoieticSGrowthSFactors
34. DrugsSUsedSinSDisordersSofSCoagulation
35. AgentsSUsedSinSDyslipidemia
36. NonsteroidalSAnti-InflammatorySDrugs,SDisease-
ModifyingSAntirheumaticSDrugs,SNonopioidSAnalgesics,S&
DrugsSUsedSinSGout
37. HypothalamicS&SPituitarySHormones
38. ThyroidS&SAntithyroidSDrugs
39. AdrenocorticosteroidsS&S AdrenocorticalS Antagonists
40. TheSGonadalSHormonesS&SInhibitors
41. PancreaticSHormonesS&SAntidiabeticSDrugs
42. AgentsSThatSAffectSBoneSMineralSHomeostasis
43. Beta-LactamS&SOtherSCellSWall-S&SMembrane-ActiveSAntibiotics
,44. Tetracyclines,SMacrolides,SClindamycin,SChloramphenicol,SStreptogramins,S &S Oxazolidinones
45. AminoglycosidesS&SSpectinomycin
46. Sulfonamides,STrimethoprim,S &S Quinolones
47. AntimycobacterialSDrugs
48. AntifungalSAgents
49. AntiviralSAgents
50. MiscellaneousSAntimicrobialS Agents;SDisinfectants,SAntiseptics,S&S Sterilants
51. ClinicalSUseSofSAntimicrobialSAgents
52. AntiprotozoalSDrugs
53. ClinicalSPharmacologySofStheSAntihelminthicSDrugs
54. CancerSChemotherapy
55. Immunopharmacology
56. IntroductionStoSToxicology:SOccupationalS&SEnvironmental
57. HeavySMetalSIntoxicationS&SChelators
58. ManagementSofStheSPoisonedSPatient
59. SpecialSAspectsSofSPerinatalS&SPediatricSPharmacology
60. SpecialSAspectsSofSGeriatricSPharmacology
61. DermatologicS Pharmacology
62. DrugsSUsedSinStheSTreatmentSofSGastrointestinalSDiseases
63. TherapeuticS&SToxicSPotentialSofSOver-the-CounterSAgents
64. DietarySSupplementsS&SHerbalSMedications
65. RationalSPrescribingS&SPrescriptionSWriting
66. ImportantSDrugSInteractionsS&STheirSMechanisms
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
S S S S S S S S S S S S
1. ASnurseSworkingSinSradiologySadministersSiodineStoSaSpatientSwhoSisShavi
ngSaScomputedStomographyS(CT)Sscan.STheSnurseSworkingSonStheSoncolo
gySunitSadministersSchemotherapyStoSpatientsSwhoShaveScancer.SAtStheSPu
blicSHealthSDepartment,SaSnurseSadministersSaSmeasles-mumps-
rubellaS(MMR)SvaccineStoaS14-month-
oldSchildSasSaSroutineSimmunization.SWhichSbranchSofSpharmacologySbest
SdescribesStheSactions
ofSallSthreeS nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
, Ans: B
Feedback:
PharmacologySisStheSstudySofStheSbiologicSeffectsSofSchemicals.SNursesSar
eSinvolvedSwithSclinicalSpharmacologySorSpharmacotherapeutics,SwhichS
isSaSbranchSofSpharmacologySthatSdealsSwithStheSusesSofSdrugsStoStreat,Spr
event,SandSdiagnoseSdisease.STheSradiologySnurseSisSadministeringSaSdru
gStoShelpSdiagnoseSaSdisease.STheSoncologySnurseSisSadministeringSaSdrugS
toShelpStreatSadisease.SPharmacoeconomicsSincludesSanyScostsSinvolvedS
inSdrugStherapy.
PharmacodynamicsSinvolvesShowSaSdrugSaffectsStheSbody
andpharmacokineticsSisShowStheSbodySactsSonStheSbody.
2.
WhenSinvolvedSinSphaseSIIISdrugSevaluationSstudies,Swh
atSresponsibilitieswouldStheSnurseShave?
A) WorkingSwithSanimalsSwhoSareSgivenSexperimentalSdrugs
B) ChoosingSappropriateSpatientsStoSbeSinvolvedSinStheSdrugS study
C) MonitoringSandSobservingSpatientsScloselySforSadverseSeffects
D) ConductingSresearchStoSdetermineSeffectivenessSofStheSdrug
Ans: C
Feedback:
PhaseSIIISstudiesSinvolveSuseSofSaSdrugSinSaSvastSclinicalSpopulationSinSw
hichpatientsSareSaskedStoSrecordSanySsymptomsStheySexperienceSwhileS
takingSthedrugs.SNursesSmaySbeSresponsibleSforShelpingScollectSandSan
alyzeStheSinformationStoSbeSsharedSwithStheSFoodSandSDrugSAdministra
tionS(FDA)SbutwouldSnotSconductSresearchSindependentlySbecauseSnur
sesSdoSnotSprescribeSmedications.SUseSofSanimalsSinSdrugStestingSisSdon
eSinStheSpreclinicalStrials.SSelectSpatientsSwhoSareSinvolvedSinSphaseSIISst
udiesStoSparticipateSinSstudiesSwhereStheSparticipantsShaveStheSdiseaseSt
heSdrugSisSintendedStoStreat.STheseSpatientsSareSmonitoredScloselySforSd
rugSactionSandSadverseSeffects.SPhaseSISstudiesSinvolveShealthyShumanS
volunteersSwhoSareSusuallySpaidSforStheirSparticipation.
NursesSmaySobserveSforSadverseSeffectsSandStoxicity.