P&A · 2A ISEH
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College of Nursing & Public Health
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A C A D E M I C E X C E L L E N C E · I N N O V AT I O N · I N T E G R I T Y · W O R L D C L A S S
EST. 1889
SERVICE
HESI A2 Anatomy and Physiology
A N ATO M Y & P H YS I O LO G Y — CO M P R E H E N S I V E R E V I E W
INSTITUTION Chamberlain University PROGRAM Pre-Nursing / Allied Health
COURSE CODE HESI A2 COURSE TITLE Anatomy & Physiology
ACADEMIC YEAR EXAM TITLE HESI A2 Anatomy and Physiology
TOTAL QUESTIONS 170 Questions FORMAT Multiple Choice — Select the
Single Best Answer
EXAMINATION INSTRUCTIONS
▸ Select the single best answer for each anatomy and physiology question.
▸ Topics include all major body systems, tissues, and directional terminology.
▸ Focus on understanding anatomical structures and physiological processes.
▸ Correct answers and rationales appear below each question.
▸ This comprehensive review covers all HESI A2 A&P content.
, SECTION I — ANATOMY & PHYSIOLOGY Questions 1 – 170
1. What is histology?
A. The study of tissues
B. The study of cells
C. The study of organs
D. The study of organ systems
CORRECT ANSWER A — The study of tissues
RATIONALE Histology is the study of tissues. Cytology is the study of cells. Anatomy is the
study of structures, and physiology is the study of function.
2. What is a tissue?
A. A group of cells that act together to perform a specific function
B. A single cell
C. A group of organs
D. A group of organ systems
CORRECT ANSWER A — A group of cells that act together to perform a specific function
RATIONALE A tissue is a group of cells that act together to perform a specific function. The
four fundamental tissue types are epithelial, connective, muscle, and nerve.
3. What are the four fundamental tissues?
A. Epithelial, connective, muscle, nerve
B. Squamous, cuboidal, columnar, transitional
C. Skeletal, cardiac, smooth, nervous
D. Dense, loose, adipose, cartilage
CORRECT ANSWER A — Epithelial, connective, muscle, nerve
RATIONALE The four fundamental tissues are epithelial, connective, muscle, and nerve
(Elephants Can Make News). Each tissue type has distinct characteristics and
functions.
, 4. What is the function of epithelial cells?
A. Cover, line, and protect the body and internal organs
B. Provide support and structure to organs
C. Contract and shorten
D. Transmit nerve impulses
CORRECT ANSWER A — Cover, line, and protect the body and internal organs
RATIONALE Epithelial cells cover, line, and protect the body and internal organs. They also
function in absorption, filtration, secretion, and sensation.
5. What is the function of connective tissue?
A. Cover, line, and protect the body
B. Framework of the body; provides support and structure to organs
C. Ability to contract and shorten
D. Transmit nerve impulses
CORRECT ANSWER B — Framework of the body; provides support and structure to organs
RATIONALE Connective tissue forms the framework of the body, providing support and
structure to organs. It is the most abundant tissue type and includes bone,
cartilage, and blood.
6. What is neuroglia?
A. The neurons and connective tissue cells that compose nerve tissue
B. The cells that cover and line organs
C. The cells that provide support and structure
D. The cells that contract and shorten
CORRECT ANSWER A — The neurons and connective tissue cells that compose nerve tissue
RATIONALE Neuroglia are the supporting cells of the nervous system. They are the connective
tissue cells that compose nerve tissue along with neurons, and they support and
protect the neurons.