RBC FULL QUESTIONS AND CORRECT
ANSWERS VERIFIED CERTIFICATION
STUDY PACK
●● Howell Jolly Bodies
Answer: -Round, purple stained fragments of DNA
-Typically singular (one dot per cell)
●● Howell Jolly bodies associated with:
Answer: -Hemolytic anemia
-Pernicious anemia
-Post splenectomy
-Splenic atrophy
●● Heinz Bodies
Answer: -Precipitated, denatured Hgb
-Need supravital stain (won't see them w/ Wright's stain)
●● Heinz bodies associated with:
Answer: -Enzyme deficiencies - G6PD
-Ingestion of oxidative drugs
,-Hemoglobinopathies
●● Pappenheimer Bodies
Answer: -Siderotic granules (iron)
-Iron in ferric form (Fe3)
-Wright's stain - purple dots
-Resembles basophilic stippling (key is clusters vs. random dots)
●● Pappenheimer bodies associated with:
Answer: -Iron loading anemias
-Splenectomy
-Hemolytic anemias
-Sideroblastic anemia
-Heoglobinopathies
●● Siderocyte
Answer: -Ringed sideroblast
-Prussian blue stain
-Iron granules form ring around nucleus
-Very rare
●● Cabot Rings
, Answer: -Very rare
-Red, dark blue, or purple
-Can vary in shape (ring, loop, folded over to form figure 8)
-Thought to be remnants of microtubules
●● Cabot rings associated with:
Answer: -Myelodysplastic syndromes
-Megaloblastic anemia
●● Hemoglobin crystals
Answer: -Rod shaped
●● Hemoglobin crystals associated with:
Answer: -Hemoglobinopathies
-->Hgb C disease
-->Hgb SC disease
●● Plasmodium
Answer: -Parasites
-Genus = plasmodium
-Diagnose with Wright's stain peripheral blood smear
-Transmitted by anopheline mosquito
ANSWERS VERIFIED CERTIFICATION
STUDY PACK
●● Howell Jolly Bodies
Answer: -Round, purple stained fragments of DNA
-Typically singular (one dot per cell)
●● Howell Jolly bodies associated with:
Answer: -Hemolytic anemia
-Pernicious anemia
-Post splenectomy
-Splenic atrophy
●● Heinz Bodies
Answer: -Precipitated, denatured Hgb
-Need supravital stain (won't see them w/ Wright's stain)
●● Heinz bodies associated with:
Answer: -Enzyme deficiencies - G6PD
-Ingestion of oxidative drugs
,-Hemoglobinopathies
●● Pappenheimer Bodies
Answer: -Siderotic granules (iron)
-Iron in ferric form (Fe3)
-Wright's stain - purple dots
-Resembles basophilic stippling (key is clusters vs. random dots)
●● Pappenheimer bodies associated with:
Answer: -Iron loading anemias
-Splenectomy
-Hemolytic anemias
-Sideroblastic anemia
-Heoglobinopathies
●● Siderocyte
Answer: -Ringed sideroblast
-Prussian blue stain
-Iron granules form ring around nucleus
-Very rare
●● Cabot Rings
, Answer: -Very rare
-Red, dark blue, or purple
-Can vary in shape (ring, loop, folded over to form figure 8)
-Thought to be remnants of microtubules
●● Cabot rings associated with:
Answer: -Myelodysplastic syndromes
-Megaloblastic anemia
●● Hemoglobin crystals
Answer: -Rod shaped
●● Hemoglobin crystals associated with:
Answer: -Hemoglobinopathies
-->Hgb C disease
-->Hgb SC disease
●● Plasmodium
Answer: -Parasites
-Genus = plasmodium
-Diagnose with Wright's stain peripheral blood smear
-Transmitted by anopheline mosquito