Midterm Exam: NR565 / NR 565 (Latest 2026 / 2027) Advanced Pharmacology Fundamental | Grade A - Chamberlain

NR565 / NR 565 Advanced Pharmacology


Midterm Exam (Latest )

Chamberlain


Foundations, Cards, Pain, MuscSkel & Rheumatologic




Question:
Glucocorticoids + Thiazides & Loops = ???
Answer:
increased risk of hypokalemia




Question:
glucocorticoids + vaccines = ???
Answer:
decreased efficacy of vaccines

,Question:
glucocorticoids + NSAIDs = ???
Answer:
GI ulcers and bleeding




Question:
glucocorticoids + insulin & oral hypoglycemics = ???
Answer:
gluconeogenesis and decreased peripheral glucose uptake




Question:
Glucocorticoid Adverse Effects (4)
Answer:
osteoporosis
myopathy
growth delays in children
eye problems: cataracts and glaucoma

,Question:
Methotrexate (Rheumatrex) MOA
Answer:
directly diminishes proliferation and function of B & T lymphocytes resulting
in decreased inflammation and tissue destruction


also disrupts DNA synthesis via dysregulation of folate




Question:
DMARDs: Considerations when initiating therapy (3)
Answer:


start DMARDs within 3 months of of RA diagnosis alongside NSAID until
therapy becomes effective


pt should be up to date on vaccines prior to initiating therapy


take with folic acid to mitigate GI and Hepatic toxicity

, Question:
Methotrexate adverse effects (4)
Answer:


hepatotoxicity
GI issues
myelosuppression
increased cardiovascular risk




Question:
RA Tx selection
Answer:


Initiate with DMARD and NSAID until DMARD takes effect, then d/c NSAID
Can add additional DMARD
Short term glucocorticoid for flares or until DMARD takes effect