CPHON PAPER EXAMS ACTUAL QUESTIONS AND
ANSWERS SURE A+
✔✔Late Effect of VCR - ✔✔Peripheral Neuropathies
✔✔Late Effect of Doxorubicin - ✔✔Cardiotoxic, Hepatic, and Secondary Malignancy
✔✔Late Effect of 6-MP - ✔✔Hepatic
✔✔Late Effect of Steroids - ✔✔Osteopenia/porosis/necrosis, Cataracts
✔✔Late Effect of Cytoxan - ✔✔Bladder/Urinary Tract (Include Cancer), Alkylating Agent
Effects (Reproductive, Thyroid, MDS, and 2nd Malignancy)
✔✔Alkylating Agent Effects - ✔✔Reproductive, Thyroid, MDS, and 2nd Malignancy
✔✔Late Effect of Ifosfamide - ✔✔Renal, Bladder, Urinary Trace (Include Cancer),
reproductive issues
✔✔Late Effect of Etoposide - ✔✔Peripheral Neuropathies, Secondary Malignancy
✔✔Late Effect of Dactinomycin - ✔✔Hepatic
✔✔Late Effect of Cisplatin and Carboplatin - ✔✔Peripheral Neuropathy, Renal,
Ototoxic, Alkylating Agent Effects
✔✔Late Effect of Bleomycin - ✔✔Pulmonary Fibrosis, interstitial Pneum
✔✔Late Effect of Carmustine/Lomustine - ✔✔Pulmonary Fibrosis, interstitial Pneum,
Alkylating Agent Effects
✔✔Late Effect of Procarbazine - ✔✔Secondary Malignancy
, ✔✔Late Effect of Temozolomide - ✔✔Secondary Malignancy, Reproductive Issues,
MDS
✔✔Late Effect of Melphalan - ✔✔Reproductive Issues, MDS
✔✔Late Effect of Busulfan - ✔✔Cataracts, hypogonadism
✔✔Late Effect of Irinotecan - ✔✔Diarrhea (Tx: Immodium. Atropine if early effect)
✔✔Phase 1 Trial - ✔✔Determine Maximum tolerated dose
✔✔Phase 2 Trial - ✔✔Investigates efficacy of a new agent treating a specific disease
✔✔Phase 3 Trial - ✔✔New drug vs. existing treatment
✔✔Phase 4 Trial - ✔✔Determines Long-term safety and efficacy
✔✔Infant Psychosocial and Cognitive Level - ✔✔Sensorimotor. Trust vs. Mistrust
✔✔Toddler Psychosocial and Cognitive Level - ✔✔Preoperational-Preconceptual.
Autonomy vs. Shame and Doubt
✔✔Preschooler Psychosocial and Cognitive Level - ✔✔Preoperational-Intuitive.
Initiative vs. Guilt
✔✔School-Age Psychosocial and Cognitive Level - ✔✔Concrete Operations. Industry
vs. inferiority
✔✔Adolescent Psychosocial and Cognitive Level - ✔✔Formal Operations. Identity vs.
Role Confusion
✔✔N-MYC Prognosis for NBL - ✔✔Bad
✔✔Genetic Factors Associated with ALL - ✔✔Trisomy 21, Fanconi, Diamond Blackfan
Syndrome, ataxia telangiectasia
✔✔Lab Values to not give Vincristine - ✔✔Low Na, ^LFT's
✔✔Prognositic for ALL (WBC, age, blasts) - ✔✔Favorable: 2-10yo, WBC <50, speed of
resp to tx
✔✔Genetics for NHL - ✔✔Wiskott-Aldrich, Ataxia Telangiectasia, SCIDS, EBV (w/ BL)
ANSWERS SURE A+
✔✔Late Effect of VCR - ✔✔Peripheral Neuropathies
✔✔Late Effect of Doxorubicin - ✔✔Cardiotoxic, Hepatic, and Secondary Malignancy
✔✔Late Effect of 6-MP - ✔✔Hepatic
✔✔Late Effect of Steroids - ✔✔Osteopenia/porosis/necrosis, Cataracts
✔✔Late Effect of Cytoxan - ✔✔Bladder/Urinary Tract (Include Cancer), Alkylating Agent
Effects (Reproductive, Thyroid, MDS, and 2nd Malignancy)
✔✔Alkylating Agent Effects - ✔✔Reproductive, Thyroid, MDS, and 2nd Malignancy
✔✔Late Effect of Ifosfamide - ✔✔Renal, Bladder, Urinary Trace (Include Cancer),
reproductive issues
✔✔Late Effect of Etoposide - ✔✔Peripheral Neuropathies, Secondary Malignancy
✔✔Late Effect of Dactinomycin - ✔✔Hepatic
✔✔Late Effect of Cisplatin and Carboplatin - ✔✔Peripheral Neuropathy, Renal,
Ototoxic, Alkylating Agent Effects
✔✔Late Effect of Bleomycin - ✔✔Pulmonary Fibrosis, interstitial Pneum
✔✔Late Effect of Carmustine/Lomustine - ✔✔Pulmonary Fibrosis, interstitial Pneum,
Alkylating Agent Effects
✔✔Late Effect of Procarbazine - ✔✔Secondary Malignancy
, ✔✔Late Effect of Temozolomide - ✔✔Secondary Malignancy, Reproductive Issues,
MDS
✔✔Late Effect of Melphalan - ✔✔Reproductive Issues, MDS
✔✔Late Effect of Busulfan - ✔✔Cataracts, hypogonadism
✔✔Late Effect of Irinotecan - ✔✔Diarrhea (Tx: Immodium. Atropine if early effect)
✔✔Phase 1 Trial - ✔✔Determine Maximum tolerated dose
✔✔Phase 2 Trial - ✔✔Investigates efficacy of a new agent treating a specific disease
✔✔Phase 3 Trial - ✔✔New drug vs. existing treatment
✔✔Phase 4 Trial - ✔✔Determines Long-term safety and efficacy
✔✔Infant Psychosocial and Cognitive Level - ✔✔Sensorimotor. Trust vs. Mistrust
✔✔Toddler Psychosocial and Cognitive Level - ✔✔Preoperational-Preconceptual.
Autonomy vs. Shame and Doubt
✔✔Preschooler Psychosocial and Cognitive Level - ✔✔Preoperational-Intuitive.
Initiative vs. Guilt
✔✔School-Age Psychosocial and Cognitive Level - ✔✔Concrete Operations. Industry
vs. inferiority
✔✔Adolescent Psychosocial and Cognitive Level - ✔✔Formal Operations. Identity vs.
Role Confusion
✔✔N-MYC Prognosis for NBL - ✔✔Bad
✔✔Genetic Factors Associated with ALL - ✔✔Trisomy 21, Fanconi, Diamond Blackfan
Syndrome, ataxia telangiectasia
✔✔Lab Values to not give Vincristine - ✔✔Low Na, ^LFT's
✔✔Prognositic for ALL (WBC, age, blasts) - ✔✔Favorable: 2-10yo, WBC <50, speed of
resp to tx
✔✔Genetics for NHL - ✔✔Wiskott-Aldrich, Ataxia Telangiectasia, SCIDS, EBV (w/ BL)
