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NSG500/ NSG 500 Test 2 (Latest 2026/2027 Update) | Complete Study Guide with Verified Q&A and Detailed Rationales | Respiratory Pharmacology | A+ Graded | Wilkes

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INSTANT PDF DOWNLOAD – This is the comprehensive Test 2 study guide for NSG 500 Advanced Health Assessment at Wilkes University (Latest 2026/2027 Update), featuring verified exam questions with correct answers and detailed rationales based on the official Wilkes University NSG 500 curriculum. Covers respiratory pharmacology (asthma, COPD, GINA/GOLD guidelines, bronchodilators, inhaled corticosteroids, methylxanthines, roflumilast), cardiovascular pharmacology (hypertension, JNC 8, heart failure, ACE inhibitors, ARBs, beta-blockers, CCBs, diuretics, digoxin), and anticoagulation pharmacology (heparin, warfarin, DOACs, antiplatelets, INR/aPTT monitoring, reversal agents). Aligned with Wilkes University NSG 500 course objectives and the 2026/2027 academic year. Key Topics & Practice Q&A Respiratory Pharmacology Q: What is the first-line treatment for persistent asthma according to GINA guidelines? A: Inhaled corticosteroids (ICS) are the first-line controller therapy for persistent asthma. Step 1: SABA as needed (intermittent). Step 2: Low-dose ICS + as-needed SABA. Step 3: Low-dose ICS-LABA. Step 4: Medium-dose ICS-LABA. Step 5: High-dose ICS-LABA + LAMA. Step 6: High-dose ICS-LABA + oral corticosteroids. Q: What are the four stages of COPD according to GOLD guidelines? A: GOLD 1 (Mild): FEV1 ≥80% predicted. GOLD 2 (Moderate): FEV1 50-79%. GOLD 3 (Severe): FEV1 30-49%. GOLD 4 (Very Severe): FEV1 30% predicted. Management includes smoking cessation, bronchodilators (LAMA/LABA), ICS, and pulmonary rehabilitation. Q: What is the mechanism of action of roflumilast? A: Roflumilast is a phosphodiesterase-4 (PDE-4) inhibitor. It inactivates cAMP, resulting in decreased cytokine release and WBC infiltration in the lungs, reducing cough and mucus production. It is reserved for severe COPD with chronic bronchitis. Q: What is the toxicity risk with methylxanthines (theophylline)? A: Risk factors for toxicity include liver disease (decreased metabolism), smoking cessation (unexpected increased levels), caffeine use (intensifies CNS/cardiac effects), and drug interactions (cimetidine, fluoroquinolones). Overdose can lead to severe dysrhythmias and seizures. Cardiovascular Pharmacology Q: What is the difference between HFrEF and HFpEF? A: HFrEF (Heart Failure with Reduced Ejection Fraction) has LVEF ≤40%. Management includes ACE inhibitors/ARBs, beta-blockers, aldosterone antagonists, diuretics, and SGLT2 inhibitors. HFpEF (Heart Failure with Preserved Ejection Fraction) has LVEF ≥50%. Management focuses on diuretics and comorbidity control. Q: What is the mechanism of action of digoxin? A: Digoxin inhibits the Na/K-ATPase pump, increasing intracellular calcium, which increases cardiac contractility (positive inotropic effect). It also slows conduction through the AV node (negative chronotropic effect). Narrow therapeutic index (0.5-2 ng/mL). Toxicity causes nausea, vomiting, visual disturbances (yellow-green halos). Q: What is the mechanism of action of ACE inhibitors? A: ACE inhibitors block the conversion of angiotensin I to angiotensin II, reducing vasoconstriction, decreasing aldosterone secretion, and reducing preload/afterload. They are first-line for hypertension and heart failure. Q: What is a common side effect of ACE inhibitors? A: Cough (dry, persistent) is a common side effect. If it occurs, switch to an ARB.

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Wilkes University




2 TSET · 005 GSN
W
Passan School of Nursing
EST. 1933
UNITY AMIDST DIVERSITY




NSG 500 Test 2
A DVA N C E D H E A LT H A SS E SS M E N T: E Y E S , E A RS , T H O RA X , C A R D I AC , A B D O M E N &
S P E C I A L P O P U L AT I O N S

INSTITUTION Wilkes University COURSE CODE NSG 500
PROGRAM Master of Science in Nursing — EXAM Test 2 — Comprehensive Systems
FNP Assessment
EXAM TITLE Wilkes NSG 500 Test 2 TOTAL QUESTIONS 150+ Questions
COURSE TITLE Advanced Health Assessment FORMAT Multiple Choice — Select the
Single Best Answer


EXAMINATION INSTRUCTIONS
▸ Select the single best answer for each question.
▸ Eye examination, ear examination, cranial nerves, thoracic and lung assessment, cardiac assessment,
abdominal assessment, breast examination, and special tests are all testable content.
▸ Visual field defects, hearing tests (Rinne/Weber), heart sounds and murmurs, abdominal signs, and
genitourinary examination are emphasized.
▸ Correct answers and clinical rationales appear below each question for comprehensive exam
preparation.
▸ All content reflects advanced health assessment standards and NSG 500 course objectives.

, SECTION I — ADVANCED HEALTH ASSESSMENT: HEAD-
Questions 1 – 150+
TO-TOE SYSTEMS EXAMINATION

1. The abbreviations for right eye, left eye, and both eyes are:
A. OD, OS, OU — OD = right, OS = left, OU = both
B. RE, LE, BE
C. OD, OS, OB
D. RT, LT, BL
CORRECT ANSWER A — OD = right, OS = left, OU = both
RATIONALE OD (oculus dexter) = right eye, OS (oculus sinister) = left eye, OU (oculus uterque)
= both eyes. These Latin abbreviations are the universal standard in
ophthalmology and medical documentation. Choice B, C, and D are incorrect or
non-standard abbreviations. The NSG 500 emphasizes using correct medical
terminology in documentation — OD/OS/OU are the accepted abbreviations for
eye examinations, prescriptions, and referrals. Understanding these terms is
essential for interpreting ophthalmology notes and communicating accurately
with eye care specialists.


2. Hyperopia is best described as:
A. Nearsightedness — difficulty seeing distant objects
B. Farsightedness — difficulty seeing close objects
C. Imperfectly shaped cornea affecting light focus
D. Impaired vision as a result of aging
CORRECT ANSWER B — Farsightedness — difficulty seeing close objects
RATIONALE Hyperopia (farsightedness) is a refractive error where light focuses behind the
retina, making close objects appear blurry while distant objects remain clear. It is
often present from childhood. Myopia (Choice A) is nearsightedness — difficulty
seeing distant objects. Astigmatism (Choice C) is an irregularly shaped cornea
causing distorted focus at all distances. Presbyopia (Choice D) is age-related loss
of lens elasticity causing difficulty with near vision after age 40. The NSG 500
emphasizes distinguishing between these four common refractive errors, as each
has different clinical implications and correction methods.

,3. The correct order of abdominal examination is:
A. Inspection, palpation, percussion, auscultation
B. Inspection, auscultation, percussion, palpation
C. Auscultation, inspection, palpation, percussion
D. Palpation, percussion, inspection, auscultation
CORRECT ANSWER B — Inspection, auscultation, percussion, palpation
RATIONALE The abdominal examination is the critical exception to the standard assessment
sequence. The correct order is: Inspection → Auscultation → Percussion →
Palpation. Auscultation is performed BEFORE percussion and palpation because
these maneuvers can stimulate peristalsis and alter bowel sounds, potentially
masking abnormalities or creating false findings. In all other body systems, the
standard sequence (Inspection → Palpation → Percussion → Auscultation)
applies. Choice A is the standard sequence for non-abdominal exams. Choice C
and D are incorrect. The NSG 500 emphasizes this exception as a key clinical
distinction — performing the abdominal exam in the wrong order can produce
misleading findings.

, 4. Bitemporal hemianopsia indicates a lesion at the:
A. Optic nerve
B. Optic chiasm — loss of both temporal visual fields
C. Optic tract
D. Occipital lobe
CORRECT ANSWER B — Optic chiasm
RATIONALE Bitemporal hemianopsia — loss of both temporal (outer) visual fields — is the
classic visual field defect produced by a lesion at the optic chiasm, most
commonly from a pituitary tumor compressing the decussating nasal retinal
fibers. This pattern occurs because fibers from the nasal (medial) retina cross at
the chiasm while temporal fibers remain ipsilateral. Optic nerve lesion (Choice A)
produces monocular blindness. Optic tract lesion (Choice C) produces
homonymous hemianopsia. Occipital lobe lesion (Choice D) also produces
homonymous visual field defects. The NSG 500 emphasizes that visual field
defects can localize neurological lesions — bitemporal hemianopsia is
pathognomonic for chiasmal compression.

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