NR 507 Edapt Unit 2
Hematological Disorders
(2026-2027)
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what are four clinical characteristics of anemia? tachycardia (due to hypoxemia), pallor, dyspnea, and fatigue
which RBC indices measures the average size of red mean corpuscular volume (MCV)
blood cells?
anemia can be caused by ______, ______, and ______. excessive blood loss, impaired RBC production, and increased RBC
destruction
which anemia is considered a microcytic anemia? iron-deficiency anemia
definition of anemia Anemia is a hematological disorder characterized by a reduction in the total
number of circulating red blood cells (RBCs) and/or a decrease in hemoglobin
(Hb) amount or function.
Complete blood count (CBC) components that relate to
RBCs and their production
microcytic anemia MCV<80 fL
- RBCs are small
- iron-deficiency anemia
- sideroblastic anemia
- thalassemia
- anemia of chronic disease
normocytic anemia MCV 80-99 fL
- RBCs are normal in size
- anemia of inflammation and chronic disease
- hereditary spherocytosis
- G6PD deficiency
- paroxysmal nocturnal hemoglobinuria
macrocytic anemia MCV > 100 fL
- RBCs are large
- B12 deficiency (pernicious anemia)
- folate deficiency
hypochromic anemia low MCHC
- RBCs have less hemoglobin than normal
- RBCs appear pale in color
normochromic normal MCHC
- RBCs have a normal amount of hemoglobin
- RBCs appear neither pale nor dark
hyperchromic high MCHC
- RBCs have more hemoglobin than normal
- RBCs appear a deeper hue of red than normal