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NURS 615: St. John’s Wort: Herbal Supplement Review | 2026 Update | Maryville University

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NURS 615: St. John’s Wort: Herbal Supplement Review | 2026 Update | Maryville University

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1
HERBAL SUPPLEMENT REVIEW




St. John’s Wort: Herbal Supplement Review




Kelsi Hayes

Maryville University




Author Note

No conflict of interest.

Correspondence concerning this article should be addressed to Kelsi Hayes, 650

Maryville University Drive, St. Louis, MO 63141. Email:

, 2
HERBAL SUPPLEMENT REVIEW
Abstract

St. John’s wort (Hypericum perforatum) is an herbal supplement widely used to treat mild-to-

moderate depression. St. John’s wort influences serotonin availability through specific enzyme

activations. However, consultation with a healthcare professional is crucial to under the risks and

potential drug-herb interactions that may occur.

Keywords: St. John’s wort, depression, drug-herb interaction, selective serotonin

reuptake inhibitors

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