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Mmsc438 Exam Script Premium Questions And Solutions Graded A+

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MMSC438 EXAM SCRIPT PREMIUM QUESTIONS AND SOLUTIONS GRADED A+

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MMSC438 EXAM SCRIPT PREMIUM
QUESTIONS AND SOLUTIONS GRADED A+

●● Cell wall inhibitors
Answer: Beta lactam
Glycopeptide


●● Beta Lactam drugs
Answer: Penicillin
Cephalosporin
Carbapenem
Monobactam


●● Glycopeptide drugs
Answer: Vancomycin
Teicoplanin


●● Links amino acids (D-ala-D-ala) in peptidoglycan
Answer: Transpeptidase (PBP)


●● Links glucans (NAM & NAG) in peptidoglycan
Answer: Transglycolase (PBP)

,●● 1st generation cephalosporins
Answer: Active against gram pos


cephalexin
cephalothin


●● 2nd generation cephalosporins
Answer: Active against gram pos and SOME gram neg
Included H. influenzae, Enterobacter, and some Neisseria


cefoxitin
cefotetan


●● 3rd generation cephalosporins
Answer: Active against gram neg and can penetrate into CSF


cefotaxime
ceftriaxone
ceftazidime


●● 4th generation cephalosporins

,Answer: Active against organism with beta lactamase


cefepime


●● 5th generation cephalosporins
Answer: Active against MRSA


ceftroline


●● Carbapenems
Answer: ertapenem
imipenem
meropenem


●● Monobactam
Answer: aztreonam


●● What are glycopeptides active against
Answer: Active against gram pos ONLY (MRSA, C.difficile)


Too large to enter gram neg (outer membrane)

, ●● What do glycopeptides do to the cell wall
Answer: Inhibit peptidoglycan synthesis


Bind to terminal D-ala-D-ala (amino acids)


Blocks cross linking


●● Plasma membrane damage drugs
Answer: Polymyxin
Colistin


●● Protein Synthesis Inhibitor Drugs
Answer: Tetracycline:
tetracycline
doxycycline


Macrolide:
erythromycin
azithromycin


Aminoglycoside:
gentamicin

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